4,274 research outputs found
Approximate quantum gates compiling with self-navigation algorithm
The compiling of quantum gates is crucial for the successful quantum
algorithm implementations. The environmental noise as well as the bandwidth of
control pulses pose a challenge to precise and fast qubit control, especially
in a weakly anharmonic system. In this work, we propose an algorithm to
approximately compile single-qubit gates with arbitrary accuracy. Evaluation
results show that the overall rotation distance generated by our algorithm is
significantly shorter than the commonly used gate, then the gate time can
be effectively shortened. The requisite number of pulses and the runtime of
scheme design scale up as with very
small prefactors, indicating low overhead costs. Moreover, we explore the
trade-off between effectiveness and cost, and find a balance point. In short,
our work opens a new avenue for efficient quantum algorithm implementations
with contemporary quantum technology.Comment: 5 pages, 2 figure
Prognostic Value of the Neo-Immunoscore in Renal Cell Carcinoma
Objective: This study evaluated the prognostic value of the newly-built Immunoscore (neo-Immunoscore) in patients with renal cell carcinoma (RCC).Methods: Eighty-two patients with RCC were enrolled in this study. Their 3- and 5-year survival rates and overall survival (OS) were evaluated. The clinicopathologic data of the 82 patients were collected and analyzed. CD3, CD4, CD8, CD45RO, Foxp3, tumor necrosis factor receptor type II (TNFR2), programmed death ligand-1 (PD-L1), CD68, programmed death-1 (PD-1), cytokeratin (CK), and indoleamine 2,3-dioxygenase (IDO) were separated into two panels and stained using multiplex fluorescent immunohistochemistry methods. An immunologic prediction model of RCC patients, the neo-Immunoscore (neo-IS), was constructed using a Cox regression model. For the prognostic prediction of RCC, the neo-IS with the immunoscore (IS) proposed by the Society for Immunotherapy of Cancer (SITC) were compared by receiver operator characteristic (ROC) curve analysis. Survivals between the neo-ISlow and neo-IShigh groups were analyzed using the Kaplan–Meier method. Multivariate Cox regression survival analysis was applied to analyze independent indicators.Results: The Cox regression model allowed the establishment of a neo-IS based on three features: CD3CT+, CD4+Foxp3+CD45ROCT+, and CD8+PD-1IM+. Compared to that of the IS proposed by the SITC, the neo-IS obtained a better prediction. The 3- and 5-year survival rates in neo-IShigh RCC patients were significantly higher than those in neo-ISlow RCC patients (94.7 vs. 77.4%, P = 0.035 and 94.7 vs. 64.5%, P = 0.002, respectively). The OS in the neo-ISlow group was significantly shorter than that in the neo-IShigh group (73 vs. 97 months, P = 0.000). In comparisons of the neo-IS with clinical pathological factors, we found that the risk stratification and neo-IS were independent factors for the prognosis of patients with RCC. Moreover, the OS rate of neo-IShigh RCC patients with low- and intermediate- risk was higher than that of neo-ISlow patients.Conclusion: The newly-constructed IS model more precisely predicted the survival of patients with RCC and may supplement the prognostic value of risk stratification
Simulation and application of loose tooling forging for heavy grinding roller shaft forgings
The grinding roller shaft is a key part of the grinding roller. It has a step-shaped shaft with different round cross-sections and 1850 mm Ă— 1110 mm rectangular cross-section. If the general method of free forging is used, the upsetting diameter of ingot will reach 2900 mm, and 8400 t hydraulic press current will not be produced so that the loose tooling forging process is to be used. The loose tooling forging process of rectangular flange has been researched by using DEFORM-3D simulation software and establishing a reasonable forging process. The production results reveal that the heavy forgings used as grinding roller shafts can be successfully produced with the present 8400 t capacity hydraulic presses. The eligible forgings have proved the rationality of the technical process
Hybrid noise protection of logical qubits for universal quantum computation
Quantum computers now show the promise of surpassing any possible classical
machine. However, errors limit this ability and current machines do not have
the ability to implement error correcting codes due to the limited number of
qubits and limited control. Therefore, dynamical decoupling (DD) and encodings
that limit noise with fewer qubits are more promising. For these reasons, we
put forth a model of universal quantum computation that has many advantages
over strategies that require a large overhead such as the standard quantum
error correcting codes. First, we separate collective noise from individual
noises on physical qubits and use a decoherence-free subspace (DFS) that uses
just two qubits for its encoding to eliminate collective noise. Second, our
bath model is very general as it uses a spin-boson type bath but without any
Markovian assumption. Third, we are able to either use a steady global magnetic
field or to devise a set of DD pulses that remove much of the remaining noise
and commute with the logical operations on the encoded qubit. This allows
removal of noise while implementing gate operations. Numerical support is given
for this hybrid protection strategy which provides an efficient approach to
deal with the decoherence problems in quantum computation and is experimentally
viable for several current quantum computing systems. This is emphasized by a
recent experiment on superconducting qubits which shows promise for increasing
the number of gates that can be implemented reliably with some realistic
parameter assumptions.Comment: 6 pages, 3 figure
Movable Fiber-Integrated Hybrid Plasmonic Waveguide on Metal Film
A waveguide structure consisting of a tapered nanofiber on a metal film is
proposed and analyzed to support highly localized hybrid plasmonic modes. The
hybrid plasmonic mode can be efficiently excited through the in-line tapered
fiber based on adiabatic conversion and collected by the same fiber, which is
very convenient in the experiment. Due to the ultrasmall mode area of plasmonic
mode, the local electromagnetic field is greatly enhanced in this movable
waveguide, which is potential for enhanced coherence light emitter
interactions, such as waveguide quantum electrodynamics, single emitter
spectrum and nonlinear optics
9-(2-ThienÂyl)-9H-carbazole
In the title compound, C16H11NS, the dihedral angles between the fused ring system and the pendant thienyl ring are 86.37 (5) and 57.14 (5)°
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