2019 Overview

The CNS Neuroscience & Therapeutics provides a medium for rapid publication of original clinical, experimental, and translational research papers, timely reviews, and reports of novel findings of therapeutic relevance to the central nervous system. Its focus includes clinical pharmacology, drug development, and novel methodologies for drug evaluation in neurological and psychiatric diseases. We are pleased to announce that CNS Neuroscience & Therapeutics has become an Open‐Access Journal as of January 2019. This would allow wider dissemination of scientific knowledge and facilitate collaborative efforts toward advancing novel and solid research on the maintenance of brain homeostasis and repairing the aging and dysfunctional brain

Data-Driven Design-by-Analogy: State of the Art and Future Directions

Design-by-Analogy (DbA) is a design methodology wherein new solutions, opportunities or designs are generated in a target domain based on inspiration drawn from a source domain; it can benefit designers in mitigating design fixation and improving design ideation outcomes. Recently, the increasingly available design databases and rapidly advancing data science and artificial intelligence technologies have presented new opportunities for developing data-driven methods and tools for DbA support. In this study, we survey existing data-driven DbA studies and categorize individual studies according to the data, methods, and applications in four categories, namely, analogy encoding, retrieval, mapping, and evaluation. Based on both nuanced organic review and structured analysis, this paper elucidates the state of the art of data-driven DbA research to date and benchmarks it with the frontier of data science and AI research to identify promising research opportunities and directions for the field. Finally, we propose a future conceptual data-driven DbA system that integrates all propositions.Comment: A Preprint Versio

Deep Learning for Technical Document Classification

In large technology companies, the requirements for managing and organizing technical documents created by engineers and managers have increased dramatically in recent years, which has led to a higher demand for more scalable, accurate, and automated document classification. Prior studies have only focused on processing text for classification, whereas technical documents often contain multimodal information. To leverage multimodal information for document classification to improve the model performance, this paper presents a novel multimodal deep learning architecture, TechDoc, which utilizes three types of information, including natural language texts and descriptive images within documents and the associations among the documents. The architecture synthesizes the convolutional neural network, recurrent neural network, and graph neural network through an integrated training process. We applied the architecture to a large multimodal technical document database and trained the model for classifying documents based on the hierarchical International Patent Classification system. Our results show that TechDoc presents a greater classification accuracy than the unimodal methods and other state-of-the-art benchmarks. The trained model can potentially be scaled to millions of real-world multimodal technical documents, which is useful for data and knowledge management in large technology companies and organizations.Comment: 16 pages, 8 figures, 9 table

Patent Data for Engineering Design: A Critical Review and Future Directions

Patent data have long been used for engineering design research because of its large and expanding size, and widely varying massive amount of design information contained in patents. Recent advances in artificial intelligence and data science present unprecedented opportunities to develop data-driven design methods and tools, as well as advance design science, using the patent database. Herein, we survey and categorize the patent-for-design literature based on its contributions to design theories, methods, tools, and strategies, as well as the types of patent data and data-driven methods used in respective studies. Our review highlights promising future research directions in patent data-driven design research and practice.Comment: Accepted by JCIS

Massive Wireless Energy Transfer without Channel State Information via Imperfect Intelligent Reflecting Surfaces

Intelligent Reflecting Surface (IRS) utilizes low-cost, passive reflecting elements to enhance the passive beam gain, improve Wireless Energy Transfer (WET) efficiency, and enable its deployment for numerous Internet of Things (IoT) devices. However, the increasing number of IRS elements presents considerable channel estimation challenges. This is due to the lack of active Radio Frequency (RF) chains in an IRS, while pilot overhead becomes intolerable. To address this issue, we propose a Channel State Information (CSI)-free scheme that maximizes received energy in a specific direction and covers the entire space through phased beam rotation. Furthermore, we take into account the impact of an imperfect IRS and meticulously design the active precoder and IRS reflecting phase shift to mitigate its effects. Our proposed technique does not alter the existing IRS hardware architecture, allowing for easy implementation in the current system, and enabling access or removal of any Energy Receivers (ERs) without additional cost. Numerical results illustrate the efficacy of our CSI-free scheme in facilitating large-scale IRS without compromising performance due to excessive pilot overhead. Furthermore, our scheme outperforms the CSI-based counterpart in scenarios involving large-scale ERs, making it a promising solution in the era of IoT

ChatDB: Augmenting LLMs with Databases as Their Symbolic Memory

Large language models (LLMs) with memory are computationally universal. However, mainstream LLMs are not taking full advantage of memory, and the designs are heavily influenced by biological brains. Due to their approximate nature and proneness to the accumulation of errors, conventional neural memory mechanisms cannot support LLMs to simulate complex reasoning. In this paper, we seek inspiration from modern computer architectures to augment LLMs with symbolic memory for complex multi-hop reasoning. Such a symbolic memory framework is instantiated as an LLM and a set of SQL databases, where the LLM generates SQL instructions to manipulate the SQL databases. We validate the effectiveness of the proposed memory framework on a synthetic dataset requiring complex reasoning. The project website is available at https://chatdatabase.github.io/

A Convolutional Neural Network-based Patent Image Retrieval Method for Design Ideation

The patent database is often used in searches of inspirational stimuli for innovative design opportunities because of its large size, extensive variety and rich design information in patent documents. However, most patent mining research only focuses on textual information and ignores visual information. Herein, we propose a convolutional neural network (CNN)-based patent image retrieval method. The core of this approach is a novel neural network architecture named Dual-VGG that is aimed to accomplish two tasks: visual material type prediction and international patent classification (IPC) class label prediction. In turn, the trained neural network provides the deep features in the image embedding vectors that can be utilized for patent image retrieval and visual mapping. The accuracy of both training tasks and patent image embedding space are evaluated to show the performance of our model. This approach is also illustrated in a case study of robot arm design retrieval. Compared to traditional keyword-based searching and Google image searching, the proposed method discovers more useful visual information for engineering design.Comment: 11 pages, 11 figure