From the zero-field metal-insulator transition in two dimensions to the quantum Hall transition: a percolation-effective-medium theory

Effective-medium theory is applied to the percolation description of the metal-insulator transition in two dimensions with emphasis on the continuous connection between the zero-magnetic-field transition and the quantum Hall transition. In this model the system consists of puddles connected via saddle points, and there is loss of quantum coherence inside the puddles. The effective conductance of the network is calculated using appropriate integration over the distribution of conductances, leading to a determination of the magnetic field dependence of the critical density. Excellent quantitative agreement is obtained with the experimental data, which allows an estimate of the puddle physical parameters

Dark energy and dark matter from an inhomogeneous dilaton

A cosmological scenario is proposed where the dark matter (DM) and dark energy (DE) of the universe are two simultaneous manifestations of an inhomogenous dilaton. The equation of state of the field is scale-dependent and pressureless at galactic and larger scales and it has negative pressure as a DE at very large scales. The dilaton drives an inflationary phase followed by a kinetic energy-dominated one, as in the "quintessential inflation" model introduced by Peebles & Vilenkin, and soon after the end of inflation particle production seeds the first inhomogeneities that lead to galaxy formation. The dilaton is trapped near the minimum of the potential where it oscillates like a massive field, and the excess of kinetic energy is dissipated via the mechanism of "gravitational cooling" first introduced by Seidel & Suen. The inhomogeneities therefore behave like solitonic oscillations around the minimum of the potential, known as "oscillatons", that we propose account for most DM in galaxies. Those regions where the dilaton does not transform enough kinetic energy into reheating or carry an excess of it from regions that have cooled, evolve to the tail of the potential as DE, driving the acceleration of the universe.Comment: 9 pages, 8 figures, uses revtex, submitted PR

Evolution of the Schr\"odinger--Newton system for a self--gravitating scalar field

Using numerical techniques, we study the collapse of a scalar field configuration in the Newtonian limit of the spherically symmetric Einstein--Klein--Gordon (EKG) system, which results in the so called Schr\"odinger--Newton (SN) set of equations. We present the numerical code developed to evolve the SN system and topics related, like equilibrium configurations and boundary conditions. Also, we analyze the evolution of different initial configurations and the physical quantities associated to them. In particular, we readdress the issue of the gravitational cooling mechanism for Newtonian systems and find that all systems settle down onto a 0--node equilibrium configuration.Comment: RevTex file, 19 pages, 26 eps figures. Minor changes, matches version to appear in PR

WMAP constraints on scalar-tensor cosmology and the variation of the gravitational constant

We present observational constraints on a scalar-tensor gravity theory by $\chi^2$ test for CMB anisotropy spectrum. We compare the WMAP temperature power spectrum with the harmonic attractor model, in which the scalar field has its harmonic effective potential with curvature $\beta$ in the Einstein conformal frame and the theory relaxes toward Einstein gravity with time. We found that the present value of the scalar coupling, i.e. the present level of deviation from Einstein gravity $(\alpha_0^2)$, is bounded to be smaller than $5\times 10^{-4-7\beta}$ ($2\sigma$), and $10^{-2-7\beta}$ ($4\sigma$) for $0< \beta<0.45$. This constraint is much stronger than the bound from the solar system experiments for large $\beta$ models, i.e., $\beta> 0.2$ and 0.3 in $2\sigma$ and $4\sigma$ limits, respectively. Furthermore, within the framework of this model, the variation of the gravitational constant at the recombination epoch is constrained as $|G(z=z_{rec})-G_0|/G_0 < 0.05(2\sigma)$, and $0.23(4\sigma)$.Comment: 7 page

Quintessence and Gravitational Waves

We investigate some aspects of quintessence models with a non-minimally coupled scalar field and in particular we show that it can behave as a component of matter with $-3 \lesssim P/\rho \lesssim 0$. We study the properties of gravitational waves in this class of models and discuss their energy spectrum and the cosmic microwave background anisotropies they induce. We also show that gravitational waves are damped by the anisotropic stress of the radiation and that their energy spectrum may help to distinguish between inverse power law potential and supergravity motivated potential. We finish by a discussion on the constraints arising from their density parameter \Omega_\GW.Comment: 21 pages, 18 figures, fianl version, accepted for publication in PR

Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells

Chimeric antigen receptor (CAR)-redirected T lymphocytes (CAR T cells) show modest therapeutic efficacy in solid tumors. The desmoplastic structure of the tumor and the immunosuppressive tumor microenvironment usually account for the reduced efficacy of CAR T cells in solid tumors. Mild hyperthermia of the tumor reduces its compact structure and interstitial fluid pressure, increases blood perfusion, releases antigens, and promotes the recruitment of endogenous immune cells. Therefore, the combination of mild hyperthermia with the adoptive transfer of CAR T cells can potentially increase the therapeutic index of these cells in solid tumors. It is found that the chondroitin sulfate proteoglycan-4 (CSPG4)-specific CAR T cells infused in Nod scid gamma mice engrafted with the human melanoma WM115 cell line have superior antitumor activity after photothermal ablation of the tumor. The findings suggest that photothermal therapy facilitates the accumulation and effector function of CAR T cells within solid tumors

Four lectures on secant varieties

This paper is based on the first author's lectures at the 2012 University of Regina Workshop "Connections Between Algebra and Geometry". Its aim is to provide an introduction to the theory of higher secant varieties and their applications. Several references and solved exercises are also included.Comment: Lectures notes to appear in PROMS (Springer Proceedings in Mathematics & Statistics), Springer/Birkhause

Galactic Halos of Fluid Dark Matter

Dwarf spiral galaxies - and in particular the prototypical DDO 154 - are known to be completely dominated by an unseen component. The putative neutralinos - so far the favored explanation for the astronomical dark matter - fail to reproduce the well measured rotation curves of those systems because these species tend to form a central cusp whose presence is not supported by observation. We have considered here a self-coupled charged scalar field as an alternative to neutralinos and investigated whether a Bose condensate of that field could account for the dark matter inside DDO 154 and more generally inside dwarf spirals. The size of the condensate turns out to be precisely determined by the scalar mass m and self-coupling lambda of the field. We find actually that for m^4 / lambda = 50 - 75 eV^4, the agreement with the measurements of the circular speed of DDO 154 is impressive whereas it lessens for larger systems. The cosmological behavior of the field is also found to be consistent - yet marginally - with the limits set by BBN on the effective number of neutrino families. We conclude that classical configurations of a scalar and self-coupled field provide a possible solution to the astronomical dark matter problem and we suggest further directions of research.Comment: 20 pages, 7 figures; one reference added, version to be published in PR

Classical and Quantum Decay of Oscillatons: Oscillating Self-Gravitating Real Scalar Field Solitons

The oscillating gravitational field of an oscillaton of finite mass M causes it to lose energy by emitting classical scalar field waves, but at a rate that is non-perturbatively tiny for small GMm, where m is the scalar field mass: d(GM)/dt ~ -3797437.776333015 e^[-39.433795197160163/(GMm)]/(GMm)^2. Oscillatons also decay by the quantum process of the annihilation of scalarons into gravitons, which is only perturbatively small in GMm, giving by itself d(GM)/dt ~ - 0.008513223934732692 G m^2 (GMm)^5. Thus the quantum decay is faster than the classical one for Gmm < 39.4338/[ln(1/Gm^2)}-7ln(GMm)+19.9160]. The time for an oscillaton to decay away completely into free scalarons and gravitons is ~ 2/(G^5 m^11) ~ 10^324 yr (1 meV/m)^11. Oscillatons of more than one real scalar field of the same mass generically asymptotically approach a static-geometry U(1) boson star configuration with GMm = GM_0 m, at the rate d(GM/c^3)/dt ~ [(C/(GMm)^4)e^{-alpha/(GMm)}+Q(m/m_{Pl})^2(GMm)^3] [(GMm)^2-(GM_0 m)^2], with GM_0 m depending on the magnitudes and relative phases of the oscillating fields, and with the same constants C, alpha, and Q given numerically above for the single-field case that is equivalent to GM_0 m = 0.Comment: 75 pages, LaTe

Scalar Field Dark Matter

This work is a review of the last results of research on the Scalar Field Dark Matter model of the Universe at cosmological and at galactic level. We present the complete solution to the scalar field cosmological scenario in which the dark matter is modeled by a scalar field $\Phi$ with the scalar potential $V(\Phi)=V_{0}(cosh {(\lambda \sqrt{\kappa_{0}}\Phi)}-1)$ and the dark energy is modeled by a scalar field $\Psi$, endowed with the scalar potential $\tilde{V}(\Psi)= \tilde{V_{0}}(\sinh{(\alpha \sqrt{\kappa_{0}}\Psi)})^{\beta}$, which together compose the 95% of the total matter energy in the Universe. The model presents successfully deals with the up to date cosmological observations, and is a good candidate to treat the dark matter problem at the galactic level.Comment: 11 pagez, 5 figures, REVTeX. To appear in proceedings of the ``Mexican Meeting on Exact Solutions and Scalar Fields in Gravity '', in honour of Heinz Dehnen's 65th Birthday and Dietrich Kramer's 60th Birthday. Mexico D.F., Mexico, in press. More info at http://www.fis.cinvestav.mx/~siddh/PHI