2,316 research outputs found

    Streaming Complexity of Spanning Tree Computation

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    The semi-streaming model is a variant of the streaming model frequently used for the computation of graph problems. It allows the edges of an n-node input graph to be read sequentially in p passes using Õ(n) space. If the list of edges includes deletions, then the model is called the turnstile model; otherwise it is called the insertion-only model. In both models, some graph problems, such as spanning trees, k-connectivity, densest subgraph, degeneracy, cut-sparsifier, and (Δ+1)-coloring, can be exactly solved or (1+ε)-approximated in a single pass; while other graph problems, such as triangle detection and unweighted all-pairs shortest paths, are known to require Ω̃(n) passes to compute. For many fundamental graph problems, the tractability in these models is open. In this paper, we study the tractability of computing some standard spanning trees, including BFS, DFS, and maximum-leaf spanning trees. Our results, in both the insertion-only and the turnstile models, are as follows. Maximum-Leaf Spanning Trees: This problem is known to be APX-complete with inapproximability constant ρ ∈ [245/244, 2). By constructing an ε-MLST sparsifier, we show that for every constant ε > 0, MLST can be approximated in a single pass to within a factor of 1+ε w.h.p. (albeit in super-polynomial time for ε ≤ ρ-1 assuming P ≠ NP) and can be approximated in polynomial time in a single pass to within a factor of ρ_n+ε w.h.p., where ρ_n is the supremum constant that MLST cannot be approximated to within using polynomial time and Õ(n) space. In the insertion-only model, these algorithms can be deterministic. BFS Trees: It is known that BFS trees require ω(1) passes to compute, but the naïve approach needs O(n) passes. We devise a new randomized algorithm that reduces the pass complexity to O(√n), and it offers a smooth tradeoff between pass complexity and space usage. This gives a polynomial separation between single-source and all-pairs shortest paths for unweighted graphs. DFS Trees: It is unknown whether DFS trees require more than one pass. The current best algorithm by Khan and Mehta [STACS 2019] takes Õ(h) passes, where h is the height of computed DFS trees. Note that h can be as large as Ω(m/n) for n-node m-edge graphs. Our contribution is twofold. First, we provide a simple alternative proof of this result, via a new connection to sparse certificates for k-node-connectivity. Second, we present a randomized algorithm that reduces the pass complexity to O(√n), and it also offers a smooth tradeoff between pass complexity and space usage.ISSN:1868-896

    Topological superconductivity in three-dimensional centrosymmetric MoTe2_2

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    One key challenge in the field of topological superconductivity (Tsc) has been the rareness of material realization. This is true not only for the first-order Tsc featuring Majorana surface modes, but also the higher-order Tsc, which host Majorana hinge and corner modes. In this work, we first propose a general material-searching "recipe" for higher-order Tsc with Majorana corner modes. This recipe is obtained from a set of symmetry indicators that can diagnose Majorana boundary patterns in centrosymmetric superconductors. We derive these indicators by establishing the bulk-boundary correspondence through a real- and momentum-space basis matching procedure. Following this recipe, we propose that centrosymmetric MoTe2_2, which was found superconducting experimentally, is a higher-order Tsc. By performing ab initio calculation and mean-field analysis for a realistic 44-band tight-binding model, we find that centrosymmetric MoTe2_2 could host Majorana corner and hinge modes. Our recipe and proposed material candidate could provide general guiding principle for material searching and designing of higher-order Tsc and mobilize experimental effort in higher-order Tsc.Comment: 5+3 pages, 3+2 figures. v2: changes in affiliation and acknowledgemen

    High-Efficiency 6′′ Multicrystalline Black Solar Cells Based on Metal-Nanoparticle-Assisted Chemical Etching

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    Multicrystalline silicon (mc-Si) photovoltaic (PV) solar cells with nanoscale surface texturing by metal-nanoparticle-assisted etching are proposed to achieve high power efficiency. The investigation of average nanorod lengths from 100 nm to 1 μm reveals that the Si wafer decorated with 100 nm thick nanorods has optical reflection of 9.5% inferior than the one with 1 μm thick nanorods (2%). However, the short nanorods improve the doping uniformity and effectively decrease metal contact resistance. After surface passivation using the hydrogenated SiO[subscript 2]/SiN[subscript x] (5 nm/50 nm) stack, the minority carrier lifetime substantially increases from 1.8 to 7.2 μs for the 100 nm-thick nanorod solar cell to achieve the high power efficiency of 16.38%, compared with 1 μm thick nanorod solar cell with 11.87%.National Science Council of Taiwan (project 100-2120-M-007-011-CC2

    Fabrication and Performance of MEMS-Based Pressure Sensor Packages Using Patterned Ultra-Thick Photoresists

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    A novel plastic packaging of a piezoresistive pressure sensor using a patterned ultra-thick photoresist is experimentally and theoretically investigated. Two pressure sensor packages of the sacrifice-replacement and dam-ring type were used in this study. The characteristics of the packaged pressure sensors were investigated by using a finite-element (FE) model and experimental measurements. The results show that the thermal signal drift of the packaged pressure sensor with a small sensing-channel opening or with a thin silicon membrane for the dam-ring approach had a high packaging induced thermal stress, leading to a high temperature coefficient of span (TCO) response of −0.19% span/°C. The results also show that the thermal signal drift of the packaged pressure sensors with a large sensing-channel opening for sacrifice-replacement approach significantly reduced packaging induced thermal stress, and hence a low TCO response of −0.065% span/°C. However, the packaged pressure sensors of both the sacrifice-replacement and dam-ring type still met the specification −0.2% span/°C of the unpackaged pressure sensor. In addition, the size of proposed packages was 4 × 4 × 1.5 mm3 which was about seven times less than the commercialized packages. With the same packaging requirement, the proposed packaging approaches may provide an adequate solution for use in other open-cavity sensors, such as gas sensors, image sensors, and humidity sensors

    Temporomandibular Joint Disorders in Patients with Rheumatoid Arthritis

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    BackgroundTemporomandibular joint disorders (TMD) are not uncommon in patients with rheumatoid arthritis (RA). However, the extent of involvement and its clinical relevance have not been well characterized. This study evaluated the correlation between the severity of RA-related TMD and RA, as well as determined the potential predictors for early identification and management of TMD in RA patients.MethodsWe sequentially recruited 56 adult RA patients from our Arthritis Clinic. TMD and RA were surveyed, clinically by questionnaires and physical examinations, and radiologically by tomography in TMD and conventional radiography in RA. The patients were stratified into no, mild and severe TMD groups according to the physical and tomographic examinations. The correlation of the severity of TMD and RA were evaluated. The relative importance of relevant predictors of severe TMD was analyzed by a logistic regression model.ResultsPhysical and radiologic temporomandibular joint abnormalities were found to be highly prevalent (85.7% and 74.5%) in these patients, and the occurrence increased to as much as 92.9% when the 2 data sets were combined. More than half of the patients had severe TMD presenting with debilitating symptoms or with a significant degree of bony destruction. The severity of TMD was variably correlated with RA severity. The score of hand-joint space narrowing was found to be the most influential predictor of severe TMD by logistic regression analysis.ConclusionThere was a high prevalence of TMD in RA patients. The severity of TMD variably correlated with RA severity. Clinically, a high score of hand-joint space narrowing may serve as an early indicator of RA patients at risk of severe TMD. This may facilitate early management and prevent the functional impairment of the temporomandibular joint

    Floating Point Arithmetic Protocols for Constructing Secure Data Analysis Application

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    AbstractA large variety of data mining and machine learning techniques are applied to a wide range of applications today. There- fore, there is a real need to develop technologies that allows data analysis while preserving the confidentiality of the data. Secure multi-party computation (SMC) protocols allows participants to cooperate on various computations while retaining the privacy of their own input data, which is an ideal solution to this issue. Although there is a number of frameworks developed in SMC to meet this challenge, but they are either tailored to perform only on specific tasks or provide very limited precision. In this paper, we have developed protocols for floating point arithmetic based on secure scalar product protocols, which is re- quired in many real world applications. Our protocols follow most of the IEEE-754 standard, supporting the four fundamental arithmetic operations, namely addition, subtraction, multiplication, and division. We will demonstrate the practicality of these protocols through performing various statistical calculations that is widely used in most data analysis tasks. Our experiments show the performance of our framework is both practical and promising

    Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1

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    <p>Abstract</p> <p>Background</p> <p>As an epigenetic regulator, the transcriptional intermediary factor 1β (TIF1β)/KAP1/TRIM28) has been linked to gene expression and chromatin remodeling at specific loci by association with members of the heterochromatin protein 1 (HP1) family and various other chromatin factors. The interaction between TIF1β and HP1 is crucial for heterochromatin formation and maintenance. The HP1-box, PXVXL, of TIF1β is responsible for its interaction with HP1. However, the underlying mechanism of how the interaction is regulated remains poorly understood.</p> <p>Results</p> <p>This work demonstrates that TIF1β is phosphorylated on Ser473, the alteration of which is dynamically associated with cell cycle progression and functionally linked to transcriptional regulation. Phosphorylation of TIF1β/Ser473 coincides with the induction of cell cycle gene <it>cyclin A2 </it>at the S-phase. Interestingly, chromatin immunoprecipitation demonstrated that the promoter of <it>cyclin A2 </it>gene is occupied by TIF1β and that such occupancy is inversely correlated with Ser473 phosphorylation. Additionally, when HP1β was co-expressed with TIF1β/S473A, but not TIF1β/S473E, the colocalization of TIF1β/S473A and HP1β to the promoters of <it>Cdc2 </it>and <it>Cdc25A </it>was enhanced. Non-phosphorylated TIF1β/Ser473 allowed greater TIF1β association with the regulatory regions and the consequent repression of these genes. Consistent with possible inhibition of TIF1β's corepressor function, the phosphorylation of the Ser473 residue, which is located near the HP1-interacting PXVXL motif, compromised the formation of TIF1β-HP1 complex. Finally, we found that the phosphorylation of TIF1β/Ser473 is mediated by the PKCδ pathway and is closely linked to cell proliferation.</p> <p>Conclusion</p> <p>The modulation of HP1β-TIF1β interaction through the phosphorylation/de-phosphorylation of TIF1β/Ser473 may constitute a molecular switch that regulates the expression of particular genes. Higher levels of phosphorylated TIF1β/Ser473 may be associated with the expression of key regulatory genes for cell cycle progression and the proliferation of cells.</p
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