621 research outputs found

    Trapping effects on inflation

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    We develop a Lagrangian approach based on the influence functional method so as to derive self-consistently the Langevin equation for the inflaton field in the presence of trapping points along the inflaton trajectory. The Langevin equation exhibits the backreaction and the fluctuation-dissipation relation of the trapping. The fluctuation is induced by a multiplicative colored noise that can be identified as the the particle number density fluctuations and the dissipation is a new effect that may play a role in the trapping with a strong coupling. In the weak coupling regime, we calculate the power spectrum of the noise-driven inflaton fluctuations for a single trapping point and studied its variation with the trapping location. We also consider a case with closely spaced trapping points and find that the resulting power spectrum is blue.Comment: 13 pages, 2 figure

    A New Seamless Bitstream Switching Scheme for H.264 Video Adaptation with Enhanced Coding Performance

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    [[abstract]]In this paper, we propose a new seamless bitstream switching scheme to improve the coding performance of H.264 SP-frames for rate adaptation. Our method removes one of the two re-quantization blocks in the SP-frame encoders so as to significantly improve coding performance. The seamless switching property of SP-frames is retained by properly restructuring the primary and secondary switching frame codecs. Experimental results show that our proposed scheme achieves close coding performance to that of regular H.264 P-frames and significantly better performance than that of SP-frames. The proposed method also provides the advantage of using a single secondary switching bitstream for both switching-up and switching-down processes[[fileno]]2030144030014[[department]]電機工程學

    Observation of interlayer phonon modes in van der Waals heterostructures

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    We have investigated the vibrational properties of van der Waals heterostructures of monolayer transition metal dichalcogenides (TMDs), specifically MoS2/WSe2 and MoSe2/MoS2 heterobilayers as well as twisted MoS2 bilayers, by means of ultralow-frequency Raman spectroscopy. We discovered Raman features (at 30 ~ 40 cm-1) that arise from the layer-breathing mode (LBM) vibrations between the two incommensurate TMD monolayers in these structures. The LBM Raman intensity correlates strongly with the suppression of photoluminescence that arises from interlayer charge transfer. The LBM is generated only in bilayer areas with direct layer-layer contact and atomically clean interface. Its frequency also evolves systematically with the relative orientation between of the two layers. Our research demonstrates that LBM can serve as a sensitive probe to the interface environment and interlayer interactions in van der Waals materials

    Inhibition of gap junctional Intercellular communication in WB-F344 rat liver epithelial cells by triphenyltin chloride through MAPK and PI3-kinase pathways

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    <p>Abstract</p> <p>Background</p> <p>Organotin compounds (OTCs) have been widely used as stabilizers in the production of plastic, agricultural pesticides, antifoulant plaints and wood preservation. The toxicity of triphenyltin (TPT) compounds was known for their embryotoxic, neurotoxic, genotoxic and immunotoxic effects in mammals. The carcinogenicity of TPT was not well understood and few studies had discussed the effects of OTCs on gap junctional intercellular communication (GJIC) of cells.</p> <p>Method</p> <p>In the present study, the effects of triphenyltin chloride (TPTC) on GJIC in WB-F344 rat liver epithelial cells were evaluated, using the scrape-loading dye transfer technique.</p> <p>Results</p> <p>TPTC inhibited GJIC after a 30-min exposure in a concentration- and time-dependent manner. Pre-incubation of cells with the protein kinase C (PKC) inhibitor did not modify the response, but the specific MEK 1 inhibitor PD98059 and PI3K inhibitor LY294002 decreased substantially the inhibition of GJIC by TPTC. After WB-F344 cells were exposed to TPTC, phosphorylation of Cx43 increased as seen in Western blot analysis.</p> <p>Conclusions</p> <p>These results show that TPTC inhibits GJIC in WB-F344 rat liver epithelial cells by altering the Cx43 protein expression through both MAPK and PI3-kinase pathways.</p

    Molecular Imaging, Pharmacokinetics, and Dosimetry of 111In-AMBA in Human Prostate Tumor-Bearing Mice

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    Molecular imaging with promise of personalized medicine can provide patient-specific information noninvasively, thus enabling treatment to be tailored to the specific biological attributes of both the disease and the patient. This study was to investigate the characterization of DO3A-CH2CO-G-4-aminobenzoyl-Q-W-A-V-G-H-L-M-NH2 (AMBA) in vitro, MicroSPECT/CT imaging, and biological activities of 111In-AMBA in PC-3 prostate tumor-bearing SCID mice. The uptake of 111In-AMBA reached highest with 3.87 ± 0.65% ID/g at 8 h. MicroSPECT/CT imaging studies suggested that the uptake of 111In-AMBA was clearly visualized between 8 and 48 h postinjection. The distribution half-life (t1/2α) and the elimination half-life (t1/2β) of 111In-AMBA in mice were 1.53 h and 30.7 h, respectively. The Cmax and AUC of 111In-AMBA were 7.57% ID/g and 66.39 h∗% ID/g, respectively. The effective dose appeared to be 0.11 mSv/MBq−1. We demonstrated a good uptake of 111In-AMBA in the GRPR-overexpressed PC-3 tumor-bearing SCID mice. 111In-AMBA is a safe, potential molecular image-guided diagnostic agent for human GRPR-positive tumors, ranging from simple and straightforward biodistribution studies to improve the efficacy of combined modality anticancer therapy

    Conformal Covariantization of Moyal-Lax Operators

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    A covariant approach to the conformal property associated with Moyal-Lax operators is given. By identifying the conformal covariance with the second Gelfand-Dickey flow, we covariantize Moyal-Lax operators to construct the primary fields of one-parameter deformation of classical WW-algebras.Comment: 13 pages, Revtex, no figures, v.2: typos corrected, references added and conclusion modifie

    Quantum Nucleation of Vortex String Loops

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    We investigate quantum nucleation of vortex string loops in the relativistic quantum field theory of a complex scalar field by using the Euclidean path integral. Our initial metastable homogeneous field dominated by the O(3)O(3) symmetric bounce solution. The nucleation rate and the critical vortex loop size are obtained approximately. Gradually the initial current will be reduced to zero as the induced current inside vortex loops is opposite to the initial current. We also discuss a similar process in Maxwell-Higgs systems and possible physical implications.Comment: phyzzx.tex, 13 pages: A correction to the final state of the nucleation of local vortex string
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