31 research outputs found
Unified syntheses of cavicularin and riccardin C: addressing the synthesis of an arene adopting a boat configuration
No full textConcise syntheses of the natural products cavicularin (ten steps) and riccardin C (seven steps) are reported. Key features of the new synthetic route are a convergent strategy to assemble acyclic precursors and a sequence of regioselective reduction and halogenation steps to facilitate Wittig macrocyclisation and transannular ring contraction reactions
Preparation of 4-(pyrazin-2-yl)pyrrolidine-2-carboxylic acid derivatives as hepatitis C virus inhibitors.
No full textPreparation of 4-(methoxycarbonyl)pyrrolidine-2-carboxylic acid derivatives as hepatitis C virus inhibitors.
No full text2-Heteroarylmethyl-4-(methoxymethyl)-N-acyl pyrrolidine compounds as antiviral agents, their preparation, pharmaceutical compositions, and use for treatment of hepatitis C.
No full text2-Heteroarylmethyl-4-(pyrazin-2-yl)-N-acyl pyrrolidine compounds as antiviral agents, their preparation, pharmaceutical compositions, and use for treatment of hepatitis C
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