3 research outputs found
Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (Nature Communications, (2021), 12, 1, (24), 10.1038/s41467-020-19366-9)
- Author
- Abecasis G.R. (Goncalo R.)
- Altshuler D. (David)
- Amin N. (Najaf)
- Amin N. (Najaf)
- An P. (Ping)
- Bakker S.J.L. (Stephan)
- Balkau B. (Beverley)
- Bandinelli S. (Stefania)
- Barroso I.E. (Inês)
- Bennett A.J. (Amanda J.)
- Bergman R.N. (Richard N.)
- Bielak L.F. (Lawrence F.)
- Blüher M. (Matthias)
- Boehm B.O. (Bernhard)
- Boehnke M. (Michael)
- Boerwinkle E.A. (Eric)
- Boettcher Y. (Yvonne)
- Bonnefond A. (Amélie)
- Boomsma D.I. (Dorret I.)
- Bornstein S.R. (Stefan)
- Bouatia-Naji N. (Nabila)
- Campbell H. (Harry)
- Campbell S. (Susan)
- Carlson O.D. (Olga)
- Dedoussis G.V. (George)
- Deloukas P. (Panos)
- Dimas A.S. (Antigone)
- Dimitriou M. (Maria)
- Doney A.S.F. (Alex)
- Duijn C.M. (Cornelia) van
- Egan J. (Josephine)
- Eriksson P. (Per)
- Esko T. (Tõnu)
- Fadista J. (João)
- Faggian A. (Alessia)
- Faire U.D. (Ulf)
- Fall T. (Tove)
- Ferrucci L. (Luigi)
- Ford I. (Ian)
- Forouhi N.G. (Nita)
- Franco-Cereceda A. (Anders)
- Franks P.W. (Paul W.)
- Frants R.R. (Rune)
- Fraser R.M. (Ross)
- Frayling T.M. (Timothy M.)
- Froguel P. (Philippe)
- Ganna A. (Andrea)
- Geus E.J.C. (Eco) de
- Giedraitis V. (Vilmantas)
- Gieger C. (Christian)
- Goel A. (Anuj)
- Grallert H. (Harald)
- Groop L. (Leif)
- Groves C.J. (Christopher J.)
- Gudnason V. (Vilmundur)
- GÃ¥din J.R. (Jesper R.)
- Hamsten A. (Anders)
- Harris T.B. (Tamara)
- Harst P. (Pim van der)
- Hastie N. (Nick)
- Hayward C. (Caroline)
- Herder C. (Christian)
- Hicks A.A. (Andrew A.)
- Hingorani A. (Aroon)
- Hofman A. (Albert)
- Horikoshi M. (Momoko)
- Hottenga J.J. (Jouke Jan)
- Hovingh G.K. (G. Kees)
- Illig T. (Thomas)
- Ingelsson E. (Erik)
- Iperen E. (Erik van)
- Isaacs A.J. (Aaron)
- Jackson A.U. (Anne U.)
- Jansen R. (Rick)
- Jarvelin M.-R. (Marjo-Riitta)
- Jiang L. (Longda)
- Johnson P.C.D. (Paul C. D.)
- Johnson T. (Toby)
- Jukema J.W. (Jan Wouter)
- Kaakinen M.A. (Marika A.)
- Kanoni S. (Stavroula)
- Kao W.H.L. (Wen)
- Kaprio J. (Jaakko)
- Kapur K. (Karen)
- Kardia S.L.R. (Sharon L. R.)
- Karpe F. (Fredrik)
- Keinanen-Kiukaanniemi S. (Sirkka)
- Kieß W. (Wieland)
- Kinnunen L. (Leena)
- Kivimaki M. (Mika)
- Kleber M.E. (Marcus E.)
- Koistinen H.A. (Heikki A.)
- Kovacs P. (Peter)
- Krus U. (Ulrika)
- Kumari M. (Meena)
- Kuusisto J. (Johanna)
- Körner A. (Antje)
- Laakso M. (Markku)
- Lagou V. (Vasiliki)
- Lakka T.A. (Timo)
- Langenberg C. (Claudia)
- Lecoeur C. (Cécile)
- Li G. (Guo)
- Lindgren C.M. (Cecilia M.)
- Lindström J. (Jaana)
- Liu Y. (Yongmei)
- Loos R.J.F. (Ruth J. F.)
- Luan J. (Jian’an)
- Lyssenko V. (Valeriya)
- Magnusson P.K. (Patrik)
- Mahajan A. (Anubha)
- Marullo L. (Letizia)
- Matullo G.
- McCarthy M.I. (Mark I.)
- McLachlan S. (Stela)
- Meigs J.B. (James B.)
- Meitinger T. (Thomas)
- Meneton P. (Pierre)
- Metspalu A. (Andres)
- Meyer J. (Julia)
- Mihailov E. (Evelin)
- Miljkovic I. (Iva)
- Min J.L. (Josine L.)
- Montasser M.E. (May E.)
- Morris A.P. (Andrew)
- Munroe P. (Patricia)
- Mägi R. (Reedik)
- Männistö S. (Satu)
- März W. (Winfried)
- Müller-Nurasyid M. (Martina)
- Navarro P. (Pau)
- Nicholson G. (George)
- Nolte I.M. (Ilja)
- O’Connell J.R. (Jeff R.)
- Palmer C.N.A. (Colin N. A.)
- Palmer C.N.A. (Colin)
- Palmer L.J. (Lyle J.)
- Pedersen N.L. (Nancy)
- Penninx B.W.J.H. (Brenda)
- Perola M. (Markus)
- Perry J.R.B. (John R. B.)
- Peyser P.A. (Patricia A.)
- Polasek O. (Ozren)
- Pourcain B.S. (Beate St)
- Pouta A. (Anneli)
- Pramstaller P.P. (Peter Paul)
- Price J.F. (Jackie F.)
- Prokopenko I. (Inga)
- Province M.A. (Michael A.)
- Rasmussen-Torvik L.J. (Laura)
- Rauramaa R. (Rainer)
- Rayner N.W. (Nigel William)
- Rudan I. (Igor)
- Rybin D. (Denis)
- Saaristo T. (Timo)
- Salo P. (Perttu)
- Salomaa V. (Veikko)
- Sanna S. (Serena)
- Sarin A.-P.
- Sattar N. (Naveed)
- Scapoli C. (Chiara)
- Schwarz P.E.H. (Peter)
- Shin S.-Y.
- Shuldiner A.R. (Alan R.)
- Shungin D. (Dmitry)
- Sijbrands E.J.G. (Eric)
- Silbernagel G. (Günther)
- Siscovick D.S. (David)
- Smith A.V. (Albert)
- Smith G.D. (George Davey)
- Snieder H. (Harold)
- Soranzo N. (Nicole)
- Stafford M.
- Stathopoulou M.G. (Maria G)
- Strawbridge R.J. (Rona)
- Stumvoll M. (Michael)
- Tanaka T. (Toshiko)
- Thorand B. (Barbara)
- Thorleifsson G. (Gudmar)
- Timpson N.J. (Nicholas J.)
- Tuomi T. (Tiinamaija)
- Tuomilehto J. (Jaakko)
- Tönjes A. (Anke)
- Ulrich A. (Anna)
- Uusitupa M. (Matti)
- Verweij N. (Niek)
- Visvikis-Siest S. (Sophie)
- Vitart V. (Veronique)
- Vollenweider P. (Peter)
- Wareham N.J. (Nick)
- Watanabe R.M. (Richard)
- Watkins H. (Hugh)
- Webster R.J. (Rebecca J.)
- Wild S.H. (Sarah)
- Willems S.M. (Sara)
- Willemsen G. (Gonneke)
- Wilson J.F. (James F.)
- Winkelmann B.
- Wolffenbuttel B.H.R. (Bruce)
- Wright A.F. (Alan F.)
- Yengo L. (Loic)
- Zemunik T. (Tatijana)
- Zudina L. (Liudmila)
- Zwart J-A. (John-Anker)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/02/2021
- Field of study
The original version of this Article contained an error in Fig. 2, in which panels a and b were inadvertently swapped. This has now been corrected in the PDF and HTML versions of the Article
Rare and low-frequency coding variants alter human adult height
- Author
- Abecasis G.R. (Gonçalo)
- Aben K.K.H. (Katja)
- Adair L.S. (Linda)
- Alam D.S. (Dewan S.)
- Albrecht E. (Eva)
- Allin K.H. (Kristine H)
- Allison M.A. (Matthew)
- Amouyel P. (Philippe)
- Angelantonio E. (Emanuele) di
- Appel E.V. (Emil V.)
- Arveiler D. (Dominique)
- Asselbergs F.W. (Folkert)
- Auer P. (Paul)
- Bakker P.I.W. (Paul) de
- Balkau B. (Beverley)
- Banas B. (Bernhard)
- Bang L.E. (Lia E.)
- Benn M. (Marianne)
- Bergmann S. (Sven)
- Bielak L.F. (Lawrence F.)
- Blüher M. (Matthias)
- Boehnke M. (Michael)
- Boeing H. (Heiner)
- Boerwinkle E.A. (Eric)
- Bonnycastle L.L. (Lori)
- Borecki I.B. (Ingrid)
- Bork-Jensen J. (Jette)
- Borst G.J. (Gert) de
- Bots M.L. (Michiel)
- Bottinger E.P. (Erwin)
- Bowden D.W. (Donald)
- Brandslund I. (Ivan)
- Breen G. (Gerome)
- Brilliant M.H. (Murray H.)
- Broer L. (Linda)
- Burt A.D. (Alastair)
- Butterworth A.S. (Adam)
- Böger C.A. (Carsten)
- Carey D.J. (David J.)
- Caulfield M. (Mark)
- Chambers J.C. (John)
- Chasman D.I. (Daniel)
- Chen Y.-D.I. (Yii-Der Ida)
- Chowdhury R. (Rajiv)
- Christensen C. (Cramer)
- Chu A.Y. (Audrey)
- Cocca M. (Massimiliano)
- Collins F.S. (Francis)
- Cook J.P. (James P.)
- Corley J. (Janie)
- Cox A.J. (Amanda J.)
- Cuellar-Partida G. (Gabriel)
- Danesh J. (John)
- Davies G. (Gail)
- De Denus S. (Simon)
- De Groot M.C.H. (Mark C.H.)
- Deary I.J. (Ian)
- Dedoussis G.V. (George)
- Deloukas P. (Panos)
- Demerath E.W. (Ellen)
- Dennis J. (Joe)
- Drenos F. (Fotios)
- Du M. (Mengmeng)
- Duijn C.M. (Cornelia) van
- Dunning A.M. (Alison M.)
- Easton D.F. (Douglas)
- Ebeling T. (Tapani)
- Edwards T.L. (Todd L.)
- Ellinor P.T. (Patrick)
- Elliott P. (Paul)
- Esko T. (Tõnu)
- Evangelou E. (Evangelos)
- Farmaki A.-E. (Aliki-Eleni)
- Faul J.D. (Jessica D.)
- Feitosa M.F. (Mary Furlan)
- Feng S. (Shuang)
- Ferrannini E. (Ele)
- Ferrario M.M. (Marco M.)
- Ferrieres J. (Jean)
- Fine R.S. (Rebecca S.)
- Florez J.C. (Jose)
- Ford I.
- Fornage M. (Myriam)
- Franks P.W. (Paul)
- Frayling T.M. (Timothy)
- Frikke-Schmidt R. (Ruth)
- Galbany J.C. (Jordi Corominas)
- Galesloot T.E. (Tessel)
- Gan W. (Wei)
- Gandin I. (Ilaria)
- Gasparini P. (Paolo)
- Giedraitis V. (Vilmantas)
- Giri A. (Ayush)
- Girotto S.
- Gordon S.D. (Scott D.)
- Gordon-Larsen P. (Penny)
- Gorski M. (Mathias)
- Graff M.J. (Maud J.L.)
- Grarup N. (Niels)
- Grove M.L. (Megan)
- Gudnason V. (Vilmundur)
- Guo X. (Xiuqing)
- Gustafsson S. (Stefan)
- Hansen T. (T.)
- Harris K.M. (Kathleen Mullan)
- Harris T.B. (Tamara)
- Hart't L.M. (Leen M.)
- Hattersley A.T. (Andrew)
- Hayward C. (Caroline)
- He L. (Liang)
- Heard-Costa N.L. (Nancy)
- Heid I.M. (Iris)
- Heikkilä K. (Kauko)
- Helgeland Ø. (Øyvind)
- Hernesniemi J. (Jussi)
- Hewit A.W. (Alex)
- Highland H. (Heather)
- Hirschhorn J.N. (Joel)
- Hocking L.J. (Lynne)
- Hollander A.I. (Anneke)
- Hollensted M. (Mette)
- Holmen O.L. (Oddgeir)
- Hovingh G.K. (Kees)
- Howson J.M.M. (Joanna M.M.)
- Hoyng C.B. (Carel)
- Huang P.L. (Paul L.)
- Hveem K. (Kristian)
- Ikram M.K. (Kamran)
- Ingelsson E. (Erik)
- Jackson A.U. (Anne)
- Jansson J.-H. (Jan-HÃ¥kan)
- Jarvik G.P. (Gail)
- Jensen G.B. (Gorm B.)
- Jhun M.A. (Min A.)
- Jia Y. (Yucheng)
- Jiang X. (Xuejuan)
- Johansson S. (Stefan)
- Jorgensen T. (Torben)
- Jousilahti P. (Pekka)
- Jukema J.W. (Jan Wouter)
- Justice A.E. (Anne)
- Jørgensen M.E. (Marit E.)
- Kahali B. (Bratati)
- Kahn R. (René)
- Kamstrup P.R. (Pia R.)
- Kanoni S. (Stavroula)
- Kao W.H.L. (Wen)
- Kaprio J. (Jaakko)
- Karaderi T. (Tugce)
- Karaleftheri M. (Maria)
- Kardia S.L.R. (Sharon L.R.)
- Karpe F. (Fredrik)
- Kathiresan S. (Sekar)
- Kee F. (Frank)
- Keeman J.N.
- Kiemeney L.A.L.M. (Bart)
- Kitajima H. (Hidetoshi)
- Kjaer T.R. (Troels R.)
- Kluivers K.B. (Kirsten B.)
- Kocher T.
- Komulainen P. (Pirjo)
- Kontto J. (Jukka)
- Kooner J.S. (Jaspal S.)
- Kooperberg C. (Charles)
- Kovacs P. (Peter)
- Kriebel J. (Jennifer)
- Kuivaniemi H. (Helena)
- Kutalik Z. (Zoltán)
- Kuusisto J. (Johanna)
- Kähönen M. (Mika)
- Küry S. (Sébastien)
- La Bianca M. (Martina)
- Laakso M. (Markku)
- Lakka T.A. (Timo)
- Lamparter D. (David)
- Lange E.M. (Ethan)
- Lange L.A. (Leslie)
- Langefeld C.D. (Carl)
- Langenberg C. (Claudia)
- Larson E.B. (Eric B.)
- Lee I.-T. (I-Te)
- Lehtimäki T. (Terho)
- Lettre G. (Guillaume)
- Lewis C.E. (Cora E.)
- Li H. (Huaixing)
- Li J. (Jin)
- Li-Gao R. (Ruifang)
- Lin H. (Honghuang)
- Lin L.-A. (Li-An)
- Lin X. (Xu)
- Lindgren C.M. (Cecilia M.)
- Lindström J. (Jaana)
- Linneberg A. (Allan)
- Liu D. (Dajiang)
- Liu Y. (Yeheng)
- Liu Y. (YongMei)
- Lo K.S.
- Locke A. (Adam)
- Loohuis L.M.O. (Loes M. Olde)
- Loos R.J.F. (Ruth)
- Lophatananon A. (Artitaya)
- Lu Y. (Yingchang)
- Luan J. (Jian'An)
- Lubitz S.A. (Steven)
- Lyytikäinen L.-P. (Leo-Pekka)
- Mackey D.A. (David A.)
- Madden P.A. (Pamela)
- Mahajan A. (Anubha)
- Manning A.K. (Alisa)
- Marenne G. (Gaëlle)
- Marouli E. (Eirini)
- Marten J. (Jonathan)
- Martin N.G. (Nicholas)
- Masca N.G.D. (Nicholas G.D.)
- Mazul A.L. (Angela L.)
- McCarthy M.I. (Mark I.)
- Medina-Gomez C. (Carolina)
- Meidtner K. (Karina)
- Metspalu A. (Andres)
- Mitchell P. (Paul)
- Mohlke K.L. (Karen)
- Mook-Kanamori D.O. (Dennis)
- Morgan A. (Anna)
- Morris A.D. (Andrew D.)
- Morris A.P. (Andrew)
- Mudgal P. (Poorva)
- Munroe P. (Patricia)
- Mutsert R. (Reneé) de
- Männistö S. (Satu)
- Müller-Nurasyid M. (Martina)
- Nalls M.A. (Michael)
- Nauck M. (Matthias)
- Nelson C.P. (Christopher P.)
- Neville M.J. (Matthew)
- Ng M.C.Y. (Maggie C.Y.)
- Nielsen S.F. (Sune)
- Nikus K. (Kjell)
- Njolstad P. (Pal)
- Nordestgaard B.G. (Børge)
- North K.E. (Kari)
- Ntalla I. (Ioanna)
- O'Connel J.R. (Jeffrey R.)
- Oksa H. (Heikki)
- Ophoff R.A. (Roel)
- Owen K.R. (Katharine R.)
- Oxvig C. (Claus)
- Packard C.J. (Chris J.)
- Padmanabhan S. (Sandosh)
- Palmer C.N.A. (Colin)
- Pasterkamp G. (Gerard)
- Patel A.P. (Aniruddh)
- Pattie A. (Alison)
- Pedersen O. (Oluf)
- Peissig P.L. (Peggy L.)
- Peloso G.M. (Gina)
- Pennell C.E. (Craig)
- Perola M. (Markus)
- Perry J.A. (James A.)
- Perry J.R.B. (John R.B.)
- Pers T.H. (Tune)
- Person A.D. (Anthony)
- Pirie A. (Ailith)
- Polasek O. (Ozren)
- Posthuma D. (Danielle)
- Raitakari O.T. (Olli T.)
- Rasheed A. (Asif)
- Rauramaa R. (Rainer)
- Reilly D.F. (Dermot F.)
- Reiner A. (Alexander)
- Renström F. (Frida)
- Ridker P.M. (Paul)
- Rioux J.D. (John)
- Rivadeneira Ramirez F. (Fernando)
- Rivas M.A. (Manuel)
- Robertson N.R. (Neil)
- Robino A. (Antonietta)
- Rolandsson O. (Olov)
- Rotter J.I. (Jerome I.)
- Rudan I. (Igor)
- Ruth K.S. (Katherine S.)
- Rüeger S. (Sina)
- Saleheen D. (Danish)
- Salomaa V. (Veikko)
- Samani N.J. (Nilesh)
- Sandow K. (Kevin)
- Sapkota Y. (Yadav)
- Sattar N. (Naveed)
- Schmidt M.K. (Marjanka)
- Schoor N.M. (Natasja) van
- Schreiner P.J. (Pamela)
- Schulze M.B. (Matthias B)
- Schurmann C. (Claudia)
- Scott R.A. (Robert)
- Segura-Lepe M.P. (Marcelo P.)
- Setten J. (Jessica) van
- Shah S.H. (Svati)
- Sim X. (Xueling)
- Sivapalaratnam S. (Suthesh)
- Small K.S. (Kerrin)
- Smith A.V. (Albert Vernon)
- Smith J.A. (Jennifer A)
- Southam L. (Lorraine)
- Spector T.D. (Timothy)
- Speliotes E.K. (Elizabeth K.)
- Starr J.M. (John)
- Steinthorsdottir V. (Valgerdur)
- Stirrups K. (Kathy)
- Stringham H.M. (Heather)
- Stumvoll M. (Michael)
- Surendran P. (Praveen)
- Tansey K.E. (Katherine E.)
- Tardif J.-C. (Jean-Claude)
- Taylor K.D. (Kent)
- Teumer A. (Alexander)
- Thompson D. (Deborah)
- Thorleifsson G. (Gudmar)
- Thorsteinsdottir U. (Unnur)
- Thuesen B.H. (Betina H.)
- Tromp G. (Gerard)
- Trompet S. (Stella)
- Tsafantakis E. (Emmanouil)
- Tuomilehto J. (Jaakko)
- Turcot V. (Valérie)
- Tybjaerg-Hansen A. (Anne)
- Tyrer J.P. (Jonathan)
- Tönjes A. (Anke)
- Uher R.
- Uitterlinden A.G. (André)
- Ulivi S. (Sheila)
- Van Der Laan S.W. (Sander W.)
- Van Der Leij A.R. (Andries R.)
- Varbo A. (Anette)
- Varga T.V. (Tibor V.)
- Varma R. (Rohit)
- Vedantam S. (Sailaja)
- Velez Edwards D.R. (Digna R.)
- Vermeulen S.H.H.M. (Sita)
- Vestergaard H. (Henrik)
- Vitart V. (Veronique)
- Vogt T.F. (Thomas F.)
- Vozzi D. (Diego)
- Walker M. (Mark)
- Wang C.A. (Carol A.)
- Wang F. (Feijie)
- Wang S. (Shuai)
- Wang Y. (Yiqin)
- Wareham N.J. (Nicholas J.)
- Warren H. (Helen)
- Wessel J. (Jennifer)
- Willems S.M. (Sara)
- Willer C.J. (Cristen)
- Wilson J.F. (James)
- Winkler T.W. (Thomas W.)
- Witte D.R. (Deniel)
- Wood A.R. (Andrew)
- Woods M.O. (Michael)
- Wu Y. (Ying)
- Yaghootkar H. (Hanieh)
- Yao J. (Jiefen)
- Yao P. (Pang)
- Yerges-Armstrong L.M. (Laura)
- Young K.L. (Kristin L.)
- Young R. (Robin)
- Zeggini E. (Eleftheria)
- Zhan X. (Xiaowei)
- Zhang W. (Weihua)
- Zhao J.H. (Jing Hua)
- Zhao W. (Wei)
- Zheng H. (He)
- Zhou W. (Wei)
- Zwart J-A. (John-Anker)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 09/02/2017
- Field of study
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencies (in the range of 0.1-4.8%) and effects of up to 2 centimetres per allele (such as those in IHH, STC2, AR and CRISPLD2), greater than ten times the average effect of common variants. In functional follow-up studies, rare height-increasing alleles of STC2 (giving an increase of 1-2 centimetres per allele) compromised proteolytic inhibition of PAPP-A and increased cleavage of
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals
- Author
- Abecasis G.R. (Goncalo R.)
- Abecasis G.R. (Goncalo R.)
- Abecasis G.R. (Gonçalo R.)
- Abecasis G.R. (Gonçalo)
- Adair L.S. (Linda)
- Allison M.A. (Matthew)
- Altshuler D. (David)
- Altshuler D. (David)
- Amin N. (Najaf)
- An P. (Ping)
- Ardlie K.G. (Kristin)
- Ardlie K.G. (Kristin)
- Ariyurek Y. (Yavuz)
- Aulchenko Y.S. (Yurii S.)
- Aulchenko Y.S. (Yurii S.)
- Aulchenko Y.S. (Yurii)
- Bacquer O.L. (Olivier)
- Balkau B. (Beverley)
- Balkau B. (Beverley)
- Ballantyne C. (Christie)
- Ballantyne C.M. (Christie M.)
- Ballantyne C.M. (Christie M.)
- Bandinelli S. (Stefania)
- Bandinelli S. (Stefania)
- Barbalic M. (maja)
- Barroso I.
- Barroso I.E. (Inês)
- Barroso I.E. (Inês)
- Barter P. (Phil)
- Beekman M. (Marian)
- Beilby J.P. (John)
- Ben-Shlomo Y.
- Benediktsson R. (Rafn)
- Benediktsson R. (Rafn)
- Bennett A.J. (Amanda)
- Bennett A.J. (Amanda)
- Bergman R.N. (Richard N.)
- Bergman R.N. (Richard N.)
- Bergman R.N. (Richard N.)
- Bergmann S.M. (Sven)
- Bidulescu A. (Aurelian)
- Bis J.C. (Joshua)
- Blagieva R. (Roza)
- Bochud M. (Murielle)
- Boehm B.O. (Bernhard)
- Boehnke M. (Michael)
- Boehnke M. (Michael)
- Boehnke M. (Michael)
- Boekholdt S.M. (Matthijs)
- Boerwinkle E. (Eric)
- Boerwinkle E. (Eric)
- Boerwinkle E.A. (Eric)
- Bonnefond A. (Amélie)
- Bonnycastle L.L. (Lori L.)
- Bonnycastle L.L. (Lori L.)
- Bonnycastle L.L. (Lori)
- Boomsma D.I. (Dorret I)
- Boomsma D.I. (Dorret I.)
- Boomsma D.I. (Dorret)
- Borch-Johnsen K.
- Borecki I.B. (Ingrid B)
- Borja J.B. (Judith)
- Boström K.B. (Kristina Bengtsson)
- Bouatia-Naji N. (Nabila)
- Bravenboer B. (Bert)
- Brunner E. (Eric)
- Buchanan T.A. (Thomas)
- Bumpstead S. (Suzannah)
- Bumpstead S. (Suzannah)
- Burtt N.P. (Noël P.)
- Burtt N.P. (Noël)
- Buxbaum S.G. (Sarah)
- Böhringer S. (Stefan)
- Böttcher Y. (Yvonne)
- Campbell H. (Harry)
- Campbell H. (Harry)
- Campbell H. (Harry)
- Cao A. (Antonio)
- Carlson O.D. (Olga)
- Cauchi S. (Stephane)
- Caulfield M. (Mark)
- Caulfield M.J. (Mark J.)
- Cavalcanti-Proença C. (Christine)
- Chambers J. (John)
- Chambers J.C. (John C.)
- Charpentier G. (Guillaume)
- Charpentier G. (Guillaume)
- Chasman D.I. (Daniel)
- Chen I. (Ida)
- Chen Y.-D.I. (Yii-Der Ida)
- Chen Y.D.I. (Yii-Der Ida)
- Chines P.S. (Peter S.)
- Chines P.S. (Peter)
- Cho Y.S. (Yoon Shin)
- Clarke R. (Robert)
- Coassin S. (Stefan)
- Coin L. (Lachlan)
- Collins F.S. (Francis S.)
- Collins F.S. (Francis S.)
- Collins F.S. (Francis)
- Cooper C. (Charles)
- Cooper C. (Cyrus)
- Cooper M.N. (Matthew)
- Cornelis M. (Marilyn)
- Cornelis M. (Marilyn)
- Couper D.J. (David J.)
- Couper D.J. (David)
- Crawford G. (Gabe)
- Crawford G. (Gabe)
- Crawford G. (Gabriel)
- Crisponi L. (Laura)
- Croteau-Chonka D.C. (Damien)
- Daly M.J. (Mark)
- Dam R.M. (Rob) van
- Dastani Z. (Zari)
- Day I.N.M. (Ian)
- Dedoussis G.V. (George)
- Dehghan A. (Abbas)
- Deloukas P. (Panagiotis)
- Deloukas P. (Panagiotis)
- Delplanque J. (Jerome)
- DIAGRAM+ Consortium
- Dina C. (Christian)
- Dina C. (Christian)
- Dominiczak A. (Anna)
- Dominiczak A.F. (Anna F.)
- Doney A.S.F. (Alex S. F.)
- Doney A.S.F. (Alex)
- Duijn C.M. (Cornelia) van
- Duncan B.B. (Bruce)
- Dupuis J. (Josée)
- Dupuis J. (Josée)
- Dupuis J. (Josée)
- Döring A. (Angela)
- Ebrahim S. (Shanil)
- Egan J.M. (Josephine)
- Egan J.M. (Josephine)
- Ejebe K.G. (Kenechi)
- Elliott A.L. (Amanda)
- Elliott A.L. (Amanda)
- Elliott K.S. (Katherine)
- Elliott P. (Paul)
- Erdmann J. (Jeanette)
- Erdmann J. (Jeanette)
- Erdos M.R. (Michael)
- Erdos M.R. (Michael)
- Evans D.M. (David)
- Faire U. (Ulf) de
- Fedson A.C. (Annette)
- Feitosa M.F. (Mary Furlan)
- Ferreira T. (Teresa)
- Ferrucci L. (Luigi)
- Ferrucci L. (Luigi)
- Fischer-Rosinsky A. (Antje)
- Florez J.C. (Jose C.)
- Florez J.C. (Jose)
- Florez J.C. (Jose)
- Forouhi N.G. (Nita)
- Fouchier S.W. (Sigrid)
- Fox C.S. (Caroline)
- Fox C.S. (Caroline)
- Franklin C.S. (Christopher)
- Franklin C.S. (Christopher)
- Franks P.W. (Paul)
- Frants R. (Rune)
- Frants R.R. (Rune)
- Franzosi M.
- Frayling T.M. (Timothy M.)
- Frayling T.M. (Timothy M.)
- Frayling T.M. (Timothy M.)
- Frayling T.M. (Timothy)
- Froguel P. (Philippe)
- Froguel P. (Philippe)
- Fuchsberger C. (Christian)
- Gabriel S.B. (Stacey)
- Galan P. (Pilar)
- Ganser M. (Martha)
- Garcia M.E. (M.)
- Geus E.J.C. (Eco) de
- Gieger C. (Christian)
- Gieger C. (Christian)
- Gieger C. (Christian)
- Gieger C. (Christian)
- Glazer N.L. (Nicole)
- GLGC Investigators
- Gloyn A.L. (Anna L.)
- Gloyn A.L. (Anna)
- Go M.J. (Min Jin)
- Goel A. (Anuj)
- Gonzalez E. (Elena)
- Goodarzi M. (Mark)
- Graessler J. (Jürgen)
- Grallert H. (Harald)
- Grallert H. (Harald)
- Grarup N. (Niels)
- Grarup N. (Niels)
- Green T. (Todd)
- Greenwood C.M.T. (Celia)
- Griffin S. (Simon)
- Grimsby J. (Jonna)
- Groop L. (Leif)
- Groop L. (Leif)
- Groop L. (Leif)
- Groves C.J. (Christopher)
- Groves C.J. (Christopher)
- Grundy S.M. (Scott)
- Gudnason V. (Vilmundur)
- Guiducci C. (Candace)
- Guiducci C. (Candace)
- Guo X. (Xiuqing)
- Guo X. (Xiuqing)
- Gwilliam R. (Rhian)
- Gyllensten U. (Ulf)
- Gyllensten U. (Ulf)
- Gyllensten U. (Ulf)
- Hadjadj S. (Samy)
- Hadjadj S. (Samy)
- Haeften T.W. (Timon) van
- Hagen K. (Knut)
- Hall A.S. (Alistair)
- Hallmans G. (Göran)
- Hammond N. (Naomi)
- Hamsten A. (Anders)
- Han X. (Xijing)
- Hansen T. (Torben)
- Haritunians T. (Talin)
- Harris T.B. (Tamara B.)
- Harris T.B. (Tamara)
- Hartikainen A.L.
- Hassanali N. (Neelam)
- Hassanali N. (Neelam)
- Hastie N. (Nick)
- Hattersley A.T. (Andrew)
- Haun M. (Margot)
- Havulinna A.S. (Aki)
- Hayward C.
- Hayward C. (Caroline)
- Heath S.C. (Simon)
- Heemst D. (Diana) van
- Hegele R.A. (Robert)
- Heid I.M. (Iris)
- Heid I.M. (Iris)
- Hengstenberg C. (Christian)
- Henneman P. (Peter)
- Henneman P. (Peter)
- Hercberg S. (Serge)
- Herder C. (Christian)
- Herder C. (Christian)
- Herpt T.W. (Thijs) van
- Hicks A.A. (Andrew A.)
- Hicks A.A. (Andrew)
- Hide W.A. (Winston)
- Hillman D.R. (David)
- Hingorani A. (Aroon)
- Hitman G.A. (Graham)
- Hivert M.-F. (Marie-France)
- Hoek M. (Mandy) van
- Hofman A.
- Hofman A. (Albert)
- Hofman A. (Albert)
- Hofman A. (Albert)
- Hofmann O.M. (Oliver)
- Holm H. (Hilma)
- Hottenga J.J. (Jouke Jan)
- Hottenga J.J. (Jouke Jan)
- Hovingh G.K. (Kees)
- Hu F.B. (Frank B)
- Hu F.B. (Frank B.)
- Hu F.B. (Frank)
- Hui J. (Jennie)
- Hung J. (Joe)
- Hunter D.J. (David)
- Huth C. (Cornelia)
- Hveem K. (Kristian)
- Igl W. (Wilmar)
- Illig T. (Thomas)
- Illig T. (Thomas)
- Ingelsson E. (Erik)
- Ingelsson E. (Erik)
- Ingelsson E. (Erik)
- Isaacs A. (Aaron)
- Isaacs A.J. (Aaron)
- Isomaa B. (Bo)
- Isomaa B. (Bo)
- Jackson A.U. (Anne)
- Jackson A.U. (Anne)
- Jarvelin M.-R. (Marjo-Riitta)
- Jarvelin M.-R. (Marjo-Riitta)
- Jarvelin M.-R. (Marjo-Riitta)
- Johansen C.T. (Christopher)
- Johansson A. (Ã…sa)
- Johnson P.R.V. (Paul R. V.)
- Johnson P.R.V. (Paul)
- Johnson T. (Toby)
- Johnson T. (Toby)
- Johnson T. (Toby)
- Jorgensen T. (Torben)
- Jorgensen T. (Torben)
- Jula A. (Antti)
- Jula A. (Antti)
- Kaakinen M. (Marika)
- Kanaya A. (Alka)
- Kanoni S. (Stavroula)
- Kanoni S. (Stavroula)
- Kao W.H.L. (W. H. Linda)
- Kao W.H.L. (Wen H. L.)
- Kao W.H.L. (Wen)
- Kao W.H.L. (Wen)
- Kaplan L. (Lee)
- Kaprio J. (Jaakko)
- Kapur K. (Karen)
- Karpe F. (Fredrik)
- Kastelein J.J.P. (John)
- Katsareli E. (Efi)
- Kedenko L. (Lyudmyla)
- Kesaniemi Y.A. (Antero)
- Khaw K.-T. (Kay-Tee)
- Khaw K.T.
- Kim Y-J. (Yong-Jin)
- Kim Y.J.
- Kivimaki M. (Mika)
- Kizer J.R. (Jorge)
- Klopp N. (Norman)
- Klopp N. (Norman)
- Kloppenburg M. (Margreet)
- Knight B. (Beatrice)
- Kong A. (Augustine)
- Kong A. (Augustine)
- Kooner J. (Jaspal)
- Koseki M. (Masahiro)
- Koskinen S. (Seppo)
- Kovacs P. (Peter)
- Kraft P. (Peter)
- Kristiansson K. (Kati)
- Kronenberg F. (Florian)
- Kronenberg F. (Florian)
- Kumari M. (Meena)
- Kuusisto J. (Johanna)
- Kuzawa C.W. (Christopher W.)
- Kuzawa C.W. (Christopher)
- Kyvik K.O. (Kirsten O.)
- Kyvik K.O. (Kirsten Ohm)
- Kähönen M. (Mika)
- König I.R. (Inke)
- Laakso M. (Markku)
- Laakso M. (Markku)
- Laakso M. (Markku)
- Laaksonen R. (Reijo)
- Ladouceur M. (Martin)
- Lajunen T. (Taina)
- Lakatta E.G. (Edward G.)
- Lamina C. (Claudia)
- Lamina C. (Claudia)
- Lange L.A. (Leslie)
- Lange L.A. (Leslie)
- Langenberg C. (Claudia)
- Langenberg C. (Claudia)
- Langenberg C. (Claudia)
- Langenberg C. (Claudia)
- Lathrop G. (GMark)
- Launer L.J. (Lenore J.)
- Lauritzen T. (Torsten)
- Lawlor D.A. (Debbie)
- Lecoeur C. (Cécile)
- Lee J.-Y. (Jong-Young)
- Lehtimäki T. (Terho)
- Lettre G. (Guillaume)
- Li M. (Man)
- Li M. (Man)
- Li X. (Xiaohui)
- Li X. (Xiaohui)
- Li Y. (Yun)
- Lieverse A.G. (Aloysius)
- Lindgren C.M. (Cecilia M.)
- Lindgren C.M. (Cecilia)
- Liu C.-T. (Ching-Ti)
- Liu Y. (YongMei)
- Lohman K. (Kurt)
- Lokki M.L.
- Loo B.-M. (Britt-Marie)
- Loos R.J.F. (Ruth)
- Loos R.J.F. (Ruth)
- Loos R.J.F. (Ruth)
- Luan J. (Jian’an)
- Luan J. (Jian’an)
- Luben R.N. (Robert)
- Lucas G. (Gavin)
- Lyssenko V. (Valeriya)
- Lyssenko V. (Valeriya)
- Lyytikäinen L.-P. (Leo-Pekka)
- MAGIC Consortium
- Magnusson P.K. (Patrik)
- Magnusson P.K.E. (Patrik K. E.)
- Mahley R. (Robert)
- Mangino M. (Massimo)
- Mangino M. (Massimo)
- Manning A.K. (Alisa K.)
- Manning A.K. (Alisa)
- Marmot M. (Michael)
- Marre M. (Michel)
- Marroni F. (Fabio)
- Martin N.G. (Nicholas)
- Martinez-Larrad M.T. (Maria Teresa)
- Masson D. (David)
- McArdle W.L. (Wendy)
- McAteer J.B. (Jarred)
- McCarroll S.A. (Steve)
- McCarroll S.A. (Steven)
- McCarthy M.I. (Mark I.)
- McCarthy M.I. (Mark I.)
- McCarthy M.I. (Mark)
- McCulloch L.J. (Laura J.)
- McCulloch L.J. (Laura)
- McPherson R. (Ruth)
- Meigs J.B. (James B.)
- Meigs J.B. (James)
- Meigs J.B. (James)
- Meisinger C. (Christa)
- Meitinger T. (Thomas)
- Meitinger T. (Thomas)
- Meitinger T. (Thomas)
- Melander O. (Olle)
- Melzer D. (David)
- Meneton P. (Pierre)
- Meulenbelt I. (Ingrid)
- Meyre D. (David)
- Midthjell K. (Kristian)
- Mitchell B.D. (Braxton)
- Mohlke K.L. (Karen L.)
- Mohlke K.L. (Karen L.)
- Mohlke K.L. (Karen L.)
- Mohlke K.L. (Karen)
- Mooser V. (Vincent)
- Mooser V. (Vincent)
- Mooser V.E. (Vincent E.)
- Morken M.A. (Mario A.)
- Morken M.A. (Mario)
- Morris A.D. (Andrew D.)
- Morris A.D. (Andrew)
- Morris A.P. (Andrew P.)
- Morris A.P. (Andrew P.)
- Morris A.P. (Andrew)
- Mukherjee S. (Sutapa)
- Munroe P. (Patricia)
- Musani S. (Solomon)
- Musunuru K. (Kiran)
- MuTHER Consortium
- Mägi R. (Reedik)
- Naitza S. (Silvia)
- Narisu N. (Narisu)
- Narisu N. (Narisu)
- Nathan D.M. (David)
- Navarro P. (Pau)
- Navarro P. (Pau)
- Neville M.J. (Matthew)
- Nickerson D.A. (Deborah A.)
- Nickerson D.A. (Deborah)
- Nieminen M.S. (Markku)
- Nilsson P. (Peter)
- Nuotio M.-L. (Marja-Liisa)
- Oostra B.A. (Ben A.)
- Oostra B.A. (Ben)
- Oostra B.A. (Ben)
- Ordovas J.M. (Jose M.)
- Ordovas J.M. (Jose)
- Orho-Melander M. (Marju)
- Orrù M. (Marco)
- Owen K.R. (Katharine)
- O’Connell J. (Jeffrey)
- Pakyz R. (Ruth)
- Palmer C. (Cameron)
- Palmer C.N.A. (Colin N. A.)
- Palmer C.N.A. (Colin)
- Pankow J.S. (James S.)
- Pankow J.S. (James)
- Paolisso G. (Giuseppe)
- Pare G. (Guillame)
- Park T. (Taesung)
- Parker A.N. (Alex)
- Pattaro C. (Cristian)
- Pattaro C. (Cristian)
- Pattou F. (François)
- Paulweber B. (Bernhard)
- Payne F. (Felicity)
- Payne F. (Felicity)
- Pearson D. (Daniel)
- Peden J. (John)
- Pedersen N.L. (Nancy)
- Pedersen O. (Oluf)
- Pedersen O. (Oluf)
- Peloso G.M. (Gina)
- Peltonen L. (Leena Johanna)
- Penninx B.W.J.H.
- Penninx B.W.J.H. (Brenda W. J. H.)
- Penninx B.W.J.H. (Brenda)
- Perola M. (Markus)
- Perola M. (Markus)
- Perola M. (Markus)
- Perry J.R.B. (John R. B.)
- Perry J.R.B. (John R. B.)
- Perry J.R.B. (John)
- Petersen A.K.
- Pfeiffer A.F.H. (Andreas)
- Pichler I. (Irene)
- Pichler I. (Irene)
- Platou C.P. (Carl)
- Polasek O. (Ozren)
- Posthuma D. (Danielle)
- Potter S.C. (Simon)
- Pouta A. (Anneli)
- Pramstaller P.P. (Peter P.)
- Pramstaller P.P. (Peter P.)
- Pramstaller P.P. (Peter Paul)
- Pramstaller P.P. (Peter Paul)
- Proença C. (Christine)
- Prokopenko I. (Inga)
- Prokopenko I. (Inga)
- Province M.A. (Mike)
- Psaty B.M. (Bruce M.)
- Psaty B.M. (Bruce)
- Qi L. (Lu)
- Qi L. (Lu)
- Quertermous T. (Thomas)
- Quertermous T. (Thomas)
- Rader D.J. (Daniel)
- Raitakari O. (Olli)
- Randall J.C. (Joshua)
- Rasmussen-Torvik L.J. (Laura)
- Rathmann W. (Wolfgang)
- Rathmann W. (Wolfgang)
- Raychaudhuri S. (Soumya)
- Rayner N.W. (Nigel W.)
- Rayner N.W. (Nigel William)
- Redline S. (Susan)
- Reilly M.P. (Muredach P.)
- Rice K.M. (Kenneth)
- Richards J.B. (J. Brent)
- Ricketts S.L. (Sally)
- Ridker P.M. (Paul)
- Rieder M. (Mark)
- Rieder M. (Mark)
- Ripatti S. (Samuli)
- Ripatti S. (Samuli)
- Rivadeneira Ramirez F. (Fernando)
- Roberts R. (Robert)
- Robertson N.R. (Neil)
- Roccasecca R.M.
- Rocheleau G. (Ghislain)
- Rocheleau G. (Ghislain)
- Roden M. (Michael)
- Roden M. (Michael)
- Rolandsson O. (Olov)
- Rose L.M. (Lynda)
- Rotter J.I. (Jerome I)
- Rudan I. (Igor)
- Rudan I. (Igor)
- Rudan I. (Igor)
- Ruokonen A. (Aimo)
- Ruokonen A. (Aimo)
- Rybin D. (Denis)
- Sabatti C. (Chiara)
- Saharinen J. (Juha)
- Salomaa V. (Veikko)
- Salomaa V. (Veikko)
- Salomaa V. (Veikko)
- Samani N.J. (Nilesh)
- Samani N.J. (Nilesh)
- Sampson M.J. (Michael J)
- Sampson M.J. (Michael)
- Sandbaek A. (Annelli)
- Sandhu M. (Manjinder)
- Sandhu M.S. (Manjinder)
- Sanna S. (Serena)
- Sanna S. (Serena)
- Sattar N. (Naveed)
- Saxena R. (Richa)
- Saxena R. (Richa)
- Sayer A.A.
- Schadt E.E. (Eric E.)
- Schadt E.E. (Eric)
- Scheet P. (Paul)
- Schlessinger D. (David)
- Schlessinger D. (David)
- Schunkert H. (Heribert)
- Schwarz P.E.H. (Peter)
- Scott L.J. (Laura J.)
- Scott L.J. (Laura)
- Scott R.A. (Robert)
- Scuteri A. (Angelo)
- Scuteri A. (Angelo)
- Scuteri A. (Angelo)
- Seedorf U. (Udo)
- Segrè A.V. (Ayellet)
- Seielstad M. (Mark)
- Semple R.K. (Robert K.)
- Serrano-RÃos M. (Manuel)
- Sethupathy P. (Praveen)
- Sharp S.J. (Stephen)
- Shields B.M. (Beverley)
- Shields B.M. (Beverley)
- Shrader P. (Peter)
- Shrader P. (Peter)
- Shuldiner A.R. (Alan)
- Sigurdsson G. (Gunnar)
- Sigursson G. (Gunnar)
- Sijbrands E. (Eric)
- Sijbrands E.J.G. (Eric J. G.)
- Sijbrands E.J.G. (Eric)
- Silander K. (Kaisa)
- Silander K. (Kaisa)
- Silveira A. (Angela)
- Sim X. (Xueling)
- Sim X. (Xueling)
- Simpson L. (Laila)
- Singleton A. (Andrew)
- Sinisalo J. (Juha)
- Siscovick D.S. (David)
- Siscovick D.S. (David)
- Sladek R. (Rob)
- Sladek R. (Rob)
- Slagboom P.E. (Eline)
- Small K.S. (Kerrin)
- Smith A.V. (Albert Vernon)
- Smith A.V. (Albert)
- Smith A.V. (Davey)
- Smith A.V. (Davey)
- Smith G.D. (George Davey)
- Smith J.D. (Joshua D.)
- Smith N.L. (Nicholas)
- Song K. (Kijoung)
- Soranzo N. (Nicole)
- Soranzo N. (Nicole)
- Sovio U. (Ulla)
- Sparsø T. (Thomas)
- Sparsø T. (Thomas)
- Spector T.D. (Tim D.)
- Spector T.D. (Timothy D.)
- Spector T.D. (Timothy)
- Spranger J. (Joachim)
- St Pourcain B. (Beate)
- Stefansson K. (Kari)
- Stefansson K. (Kari)
- Stein L.D. (Lincoln)
- Steinthorsdottir V. (Valgerdur)
- Steinthorsdottir V. (Valgerdur)
- Strachan D.P. (David)
- Strassburger K. (Klaus)
- Stringham H.M. (Heather M.)
- Stringham H.M. (Heather M.)
- Stringham H.M. (Heather)
- Stumvoll M. (Michael)
- Stylianou I.M. (Ioannis M.)
- Stylianou I.M. (Ioannis)
- Sun Q. (Qi)
- Surakka I. (Ida)
- Swift A.J. (Amy)
- Swift A.J. (Amy)
- Syddall H. (Holly)
- Syvänen A.C.
- Tai E.-S. (E-Shyong)
- Tai E.S. (Shyong)
- Tall A.R. (Alan R.)
- Tanaka T. (Toshiko)
- Taylor H.A. (Herman A.)
- Taylor H.A. (Herman)
- Teslovich T.M. (Tanya M.)
- Teslovich T.M. (Tanya M.)
- Thompson J.R. (John)
- Thompson J.R. (John)
- Thorand B. (Barbara)
- Thorand B. (Barbara)
- Thorleifsson G. (Gudmar)
- Thorleifsson G. (Gudmar)
- Thorleifsson G. (Gudmar)
- Thorsteinsdottir U. (Unnur)
- Thorsteinsdottir U. (Unnur)
- Thorsteinsdottir U. (Unnur)
- Thorsteinsdottir U. (Unnur)
- Tichet J. (Jean)
- Tichet J. (Jean)
- Timpson N.J. (Nicholas J.)
- Timpson N.J. (Nicholas)
- Tracy R.P. (Russell)
- Tuomi T. (Tiinamaija)
- Tuomi T. (Tiinamaija)
- Tuomilehto J. (Jaakko)
- Tuomilehto J. (Jaakko)
- Tuomilehto J. (Jaakko)
- Tönjes A. (Anke)
- Uda M. (Manuela)
- Uda M. (Manuela)
- Uh H.-W. (Hae-Won)
- Uitterlinden A. (Andre)
- Uitterlinden A.G. (Andre G.)
- Uitterlinden A.G. (André)
- Valle T.T. (Timo T.)
- van Duijn C. (Cornelia)
- van Duijn C.M. (Cornelia M.)
- van Duijn C.M. (Cornelia M.)
- van Hoek M. (Mandy)
- Varma D. (Dhiraj)
- Viikari J. (Jorma)
- Visvikis-Siest S. (Sophie)
- Vitart V. (Veronique)
- Vitart V. (Veronique)
- Vliet-Ostaptchouk J.V. (Jana) van
- Vogelzangs N. (Nicole)
- Voight B.F. (Benjamin F.)
- Voight B.F. (Benjamin F.)
- Voight B.F. (Benjamin)
- Vollenweider P. (Peter)
- Vollenweider P. (Peter)
- Vollenweider P. (Peter)
- Waeber G. (Gérard)
- Waeber G. (Gérard)
- Wagner P.J. (Peter)
- Walker M. (Mark)
- Walley A. (Andrew)
- Walters G. (GBragi)
- Walters G.B. (Bragi)
- Ward K.L. (Kim L.)
- Wareham N.J. (Nick J.)
- Wareham N.J. (Nick)
- Wareham N.J. (Nick)
- Watanabe R.M. (Richard M.)
- Watanabe R.M. (Richard)
- Waterworth D. (Dawn)
- Waterworth D. (Dawn)
- Waterworth D.M. (Dawn)
- Watkins H. (Hugh)
- Weedon M.N. (Michael)
- Weedon M.N. (Michael)
- Welch R.P. (Ryan)
- Wheeler E. (Eleanor)
- Whitfield J. (John)
- Wichmann H.-E. (H.-Erich)
- Wichmann H.E. (H. Erich)
- Wichmann H.E. (Heinz Erich)
- Wichmann H.E. (Heinz Erich)
- Wijmenga C. (Cisca)
- Wild S.H. (Sarah)
- Willems van Dijk J.A.P. (Ko)
- Willems S.M. (Sara)
- Willems-vanDijk K. (Ko)
- Willemsen G.
- Willemsen G.A.H.M. (Gonneke)
- Willer C.J. (Cristen J.)
- Willer C.J. (Cristen)
- Williams G.H. (Gordon)
- Wilson J.F. (James F.)
- Wilson J.F. (James)
- Wilson J.G. (James G.)
- Winkler T.W. (Thomas W.)
- Witteman J. (Jacqueline)
- Witteman J.C.M. (Jacqueline C. M.)
- Witteman J.C.M. (Jacqueline)
- Witteman J.C.M. (Jaqueline C. M.)
- Wong T.Y. (Tien Y.)
- Wood A.R. (Andrew)
- Wright A.F. (Alan)
- Wright A.F. (Alan)
- Wu G. (Guanming)
- Wu Y. (Ying)
- Yarnell J.W.G. (John W.)
- Yuan X. (Xin)
- Zabena C. (Carina)
- Zee R.Y.L. (Robert)
- Zeggini E. (Eleftheria)
- Zeggini E. (Eleftheria)
- Zelenika D. (Diana)
- Zethelius B. (Björn)
- Zhai G. (Guangju)
- Zhang W. (Weihua)
- Zhao J.H. (Jing Hua)
- Zhao J.H. (Jing Hua)
- Zhao J.H. (Jing Hua)
- Ziegler A. (Andreas)
- Zillikens M.C. (Carola)
- Zwart J-A. (John-Anker)
- Ódonnell C.J. (Christopher)
- Publication venue
- Publication date
- 01/01/2012
- Field of study
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease. We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (P = 4.5×10−8- 1.2 ×10−43). Using a novel method to combine data across ethnicities (N = 4,232 African Americans, N = 1,776 Asians, and N = 29,347 Europeans), we identified two additional novel loci. Expression analyses of 436 human adipocyte samples revealed that mRNA levels of 18 genes at candidate regions were associated with adiponectin concentrations after accounting for multiple testing (p<3×10−4). We next developed a multi-SNP genotypic risk score to test the association of adiponectin decreasing risk alleles on metabolic traits and diseases using consortia-level meta-analytic data. This risk score was associated with increased risk of T2D (p = 4.3×10−3, n = 22,044), increased triglycerides (p = 2.6×10−14, n = 93,440), increased waist-to-hip ratio (p = 1.8×10−5, n = 77,167), increased glucose two hours post oral glucose tolerance testing (p = 4.4×10−3, n = 15,234), increased fasting insulin (p = 0.015, n = 48,238), but with lower in HDL- cholesterol concentrations (p = 4.5×10−13, n = 96,748) and decreased BMI (p = 1.4×10−4, n = 121,335). These findings identify novel genetic determinants of adiponectin levels, which, taken together, influence risk of T2D and markers of insulin resistance