In-hospital cardiovascular events after liver transplantation: predictors and long-term outcome

Introduction: Liver transplantation has emerged as a successful therapy for end-stage liver disease. However, cardiovascular mortality is the leading cause of fatality in the postoperative period. The aim of this study was to reveal the prevalence and identify risk factors of early cardiovascular events (CVEs). Methods: We performed a retrospective study of all consecutive patients who underwent a primary liver transplantation from 1986 to 2017 (n = 916). We investigated the occurrence of in-hospital CVEs, their predictors, and short- and long-term outcome. Results: The prevalence of CVEs was 11%. The adjusted analysis showed that higher age (OR 1.06, 95% CI 1.03–1.09), higher MELD score (OR 1.04, 95% CI 1.01–1.07 CI) and sinus tachycardia at time of screening (OR 3.12, 95% CI 1.45–6.72) we

Responsible domestic robotics:Exploring ethical implications of robots in the home

Purpose: The vision of robotics in the home promises increased convenience, comfort, companionship, and greater security for users. The robot industry risks causing harm to users, being rejected by society at large, or being regulated in overly prescriptive ways if robots are not developed in a socially responsible manner. The purpose of this paper is to explore some of the challenges and requirements for designing responsible domestic robots.Design/methodology/approach: The paper examines definitions of robotics and the current commercial state of the art. In particular it considers the emerging technological trends, such as smart homes, that are already embedding computational agents in the fabric of everyday life. The paper then explores the role of values in design, aligning with human computer interaction and considers the importance of the home as a deployment setting for robots. The paper examines what responsibility in robotics means and draws lessons from past home information technologies. An exploratory pilot survey was conducted to understand user concerns about different aspects of domestic robots such as form, privacy and trust. The paper provides these findings, married with literature analysis from across technology law, computer ethics and computer science.Findings: By drawing together both empirical observations and conceptual analysis, this paper concludes that user centric design is needed to create responsible domestic robotics in the future.Originality/value: This multidisciplinary paper provides conceptual and empirical research from different domains to unpack the challenges of designing responsible domestic robotics

Responsibility and innovation

Ethics & Philosophy of Technolog

Ethics and the UN Sustainable Development Goals: The Case for Comprehensive Engineering: Commentary on “Using Student Engagement to Relocate Ethics to the Core of the Engineering Curriculum”

In the twenty-first century, the urgent problems the world is facing (the UN Sustainable Development Goals) are increasingly related to vast and intricate ‘systems of systems’, which comprise both socio-technical and eco-systems. In order for engineers to adequately and responsibly respond to these problems, they cannot focus on only one technical or any other aspect in isolation, but must adopt a wider and multidisciplinary perspective of these systems, including an ethical and social perspective. Engineering curricula should therefore focus on what we call ‘comprehensive engineering’. Comprehensive engineering implies ethical coherence, consilience of scientific disciplines, and cooperation between parties.Values Technology and Innovatio