Exact solution for large amplitude flexural vibration of nanobeams using nonlocal Euler-Bernoulli theory

In this paper, nonlinear free vibration of nanobeams with various end conditions is studied using the nonlocal elasticity within the frame work of Euler-Bernoulli theory with von K´arm´an nonlinearity. The equation of motion is obtained and the exact solution is established using elliptic integrals. Two comparison studies are carried out to demonstrate accuracy and applicability of the elliptic integrals method for nonlocal nonlinear free vibration analysis of nanobeams. It is observed that the phase plane diagrams of nanobeams in the presence of the small scale effect are symmetric ellipses, and consideration the small scale effect decreases the area of the diagram

Simultaneous Determination of Nitrite and Nitrate in Milk Samples by Ion Chromatography Method and Estimation of Dietary Intake

The presence of nitrate and nitrite in foods may be considered hazardous after ingestion in the gastrointestinal tract due to their reaction with naturally occurred secondary amines to form potentially carcinogenic nitrosamines. Due to this fact, a new method was developed in this study for the simultaneous determination of nitrite and nitrate in milk samples using by ion chromatography. Proposed mobile phase composed of sodium hydrogen carbonate and sodium carbonate (1.0 and 3.2 mmol/L) with a flow rate of 0.7 ml/min. The average recoveries for nitrate and nitrite were higher than 86 and 88, respectively. The limit of detection for nitrate and nitrite were 0.24 and 0.09 mg/L, respectively. The results of 102 real milk samples showed nitrate was found in all of the samples (100) with a mean of 34 ± 11 mg/L, while nitrite was found in none of the samples. The mean intake of nitrate in all age groups was lower than World Health Organization guideline. The present assessment concludes that the maximum contaminant level was equal to 82.8 mg/L nitrate. This method was fast, sensitive and accurate and is capable of being an alternative method in food control laboratories for investigation of nitrite and nitrate content. This is the first study of the determination and survey of nitrite and nitrate and exposure assessment of the Iranian population to nitrite and nitrate level in milk, which was widely used in infants and adolescents as one of the basic food components. Copyright © Taylor & Francis Group, LLC

Electrophysiological and molecular mechanisms of protection by iron sucrose against phosphine-induced cardiotoxicity: A time course study

The present study was designed for determining the exact mechanism of cytotoxic action of aluminum phosphide (AlP) in the presence of iron sucrose as the proposed antidote. Rats received AlP (12 mg/kg) and iron sucrose (5-30 mg/kg) in various sets and were connected to cardiovascular monitoring device. After identification of optimum doses of AlP and iron sucrose, rats taken in 18 groups received AlP (6 mg/kg) and iron sucrose (10 mg/kg), treated at six different time points, and then their hearts were surgically removed and used for evaluating a series of mitochondrial parameters, including cell lipid peroxidation, antioxidant power, mitochondrial complex activity, ADP/ATP ratio and process of apoptosis. ECG changes of AlP poisoning, including QRS, QT, P-R, ST, BP and HR were ameliorated by iron sucrose (10 mg/kg) treatment. AlP initiated its toxicity in the heart mitochondria through reducing mitochondrial complexes (II, IV and V), which was followed by increasing lipid peroxidation and the ADP/ATP ratio and declining mitochondrial membrane integrity that ultimately resulted in cell death. AlP in acute exposure (6 mg/kg) resulted in an increase in hydroxyl radicals and lipid peroxidation in a time-dependent fashion, suggesting an interaction of delivering electrons of phosphine with mitochondrial respiratory chain and oxidative stress. Iron sucrose, as an electron receiver, can compete with mitochondrial respiratory chain complexes and divert electrons to another pathway. The present findings supported the idea that iron sucrose could normalize the activity of mitochondrial electron transfer chain and cellular ATP level as vital factors for cell escaping from AlP poisoning. © 2015 Informa Healthcare USA, Inc. All rights reserved

NREL Phase VI wind turbine in the dusty environment

The meteorological conditions markedly affect the energy efficiencies and cost/power rate of the wind turbines. This study numerically investigates the performance of the National Renewable Energy Laboratory (NREL) Phase VI wind turbine, designed to be insusceptible to surface roughness, undergoing either clean or dusty air. First, the numerical approach is validated against the available experimental data for clean air. Following this, the model is developed into a Lagrangian-Eulerian multiphase approach to comprehensively analyze the effects of the dusty air. The dependence of aerodynamic performance on the wind speed (= 5-25 m/s), particle diameter dp (= 0.025-0.9 mm) and angle of attack (= 0o-44o) is investigated. It is found that the turbine performance generally deteriorates in dusty conditions. But it becomes relatively acute for dp > 0.1 mm and post-stall state. As such, the generated power is reduced by 4.3% and 13.3% on average for the air with the dp = 0.05 and 0.9 mm, respectively. The particles change the flow field profoundly, declining the pressure difference between the suction/pressure sides of the blade-airfoil, advancing the boundary layer separation, and strengthening the recirculation zones. The above changes account for a lower lift coefficient and higher drag coefficient

Modified Dolphin Monitoring Operator for Weight Optimization of Frame Structures

In this article, a modified dolphin monitoring (MDM) operatoris introduced and used to improve the performance of the collidingbodies optimization (CBO) algorithm for optimal designof steel structures (CBO-MDM). The performance of the CBO,enhanced colliding bodies optimization (ECBO) and CBOMDMare compared through three well-established structuralbenchmarks. The optimized designs obtained by thesealgorithms are compared, and the results show that the performanceof CBO-MDM is superior to those of the other twoalgorithms. The MDM is found to be a suitable tool to enhancethe performance of the CBO algorithm