<title>High-speed multichannel optical telemetering system</title>

Machine tool, in-line and robot sensors and controls : Conference : Oct 1995, Philadelphia, PAAn optical telemetering system which measures the temperature of the rotating spindle of a machine is proposed. Our system uses an optical data transmission to realize high-speed precise telemetering, it is robust for the external electric-magnetic field. Moreover it can measure the temperatures at eight different positions simultaneously and the data is transmitted with only two pairs of infrared LED and photodiode by using an asynchronous serial data transmission. We have made an experimental system and measured some fundamental characteristics. The time required for the data transmission is 48 μs a channel. It is confirmed experimentally that the accuracy in temperature measurement is 0.4 °C

Growth and characterization of strontium-substituted Ca2Al2SiO7 piezoelectric single crystals

International audienceWe report the effect of Sr substitution on the structural, electrical, and mechanical properties of Ca2Al2SiO7 (CAS) piezoelectric single crystals for high-temperature pressure sensors. Single crystals of Sr-substituted CAS (Sr-CAS) with a nominal chemical composition of CaSrAl2SiO7 were grown by using the Czochralski technique. The single-crystal X-ray structure analysis revealed that Sr atoms were placed in the Ca decahedral sites, which decreased the polyhedral distortion slightly. The piezoelectric modulus d′31 and electrical resistivity of Sr-CAS measured at 23°C were slightly lower than those of CAS, but still sufficient for the satisfactory performance of the produced sensors. The rupture strength of the Sr-CAS crystal was 230 MPa, 1.2 times higher than that of a CAS crystal. The obtained results suggest that Sr-CAS crystals can be candidate materials for high-temperature pressure sensors

Knockdown of proteolipid protein 2 or focal adhesion kinase with an artificial microRNA reduces growth and metastasis of B16BL6 melanoma cells

Proteolipid protein 2 (PLP2) promotes the metastasis of B16F10 cells in an experimental metastasis model. However, the effect of PLP2 on spontaneous metastasis has yet to be demonstrated, and whether PLP2 may become a new therapeutic target for malignant tumors is as yet unknown. In this study, PLP2 or focal adhesion kinase (FAK) microRNA-based short hairpin RNAs (miRNAs) were used as target molecules to specifically reduce the expression of PLP2 or FAK in B16BL6 cells. In vitro, the knockdown of PLP2 or FAK significantly inhibited cell proliferation, adhesion, migration and invasion. In a spontaneous metastatic tumor model using a footpad injection, the knockdown of PLP2 or FAK markedly inhibited the proliferation of the primary tumor and prevented tumor cells from invading the popliteal lymph nodes. The results indicate that downregulation of PLP2 or FAK may improve outcomes of malignant tumor therapy