Need for Nurse Practitioner Fellowships in Ophthalmology in the USA

Medical attention to vision impairment and associated eye care complications are a vital component of daily living and overall well-being. In the United States today, the physician to patient deficit places great strain on the availability of medical attention tenable to patients nationwide; in terms of specialty medicine, this deficit is even more widespread. The field of ophthalmology faced the same physician to patient deficit in 2020, a grim reality that has left many states void of ophthalmic care, rending millions of aging individuals without domestic eye care. The implementation of trained, ophthalmic nurse practitioners (NPs) can fill the needs of this deficit; however, efficient, accredited, and board-approved American ophthalmic fellowships and residencies that secure proper ophthalmic NP transitions from academia to clinical practice are nonexistent. Though scant, evidence-based literature presents sound findings that support the efficacy and benefit for superior patient outcomes with care provided by ophthalmictrained NPs, offering a viable, long-term solution to the need for ophthalmic medical providers across all states without mitigating patient care, emphasizing the great need for the implementation of ophthalmic NP residencies and fellowships to ensure the continuity of impeccable ophthalmic care for all populations

Radiological anatomy of distal phalanx of front foot in the pure Iranian Arabian horse

Background: Among the different breeds of horses, Asil horses with a five thousand year history have played an important role in human life. This study was designed as a result of the lack of information about the normal radiographic anatomy of this breed. Materials and methods: Radiography of the distal phalanx and associated soft tissue structures of the front feet of 10 healthy pure Iranian Arabian horses was performed on lateromedial radiographic projection to determine normal radiographic morphometry of this part. There were no problems in their limbs and in their history. Results: Obtained radiograph of each front distal phalanx was used to measure important distances, angles and ratios of the hoof wall. There was no significant difference between left and right digits for any radiographic determination. Conclusions: Measurements of this study differed from those reported in other breeds, so it can be used in the future as reference values for diagnosis of laminitis in front feet of Iranian Arabian horses.

Microtensile bond strength of ceramic to resin using different silanes

Oral Session - Dental Materials 1: Adhesion - Bond Strength Testing and Mechanisms: 9. Cement Adhesion to Ceramics: no. 27OBJECTIVES: The purpose of this study was to assess the micro-tensile bond strength of a leucite-reinforced feldspathic ceramic to a resin cement using different types of silane primers. METHODS: 18 leucite-reinforced feldspathic ceramic blocks (Ceramco II, Dentsply) in dimensional of 6×6×6 mm were fabricated. The ceramic blocks were ground on wet SiC papers and then cleansed ultrasonically in distilled water. The bonding ceramic surfaces were treated with different silane solutions as follows: Commercial silane as control: Monobond S (Ivoclar-Vivadent); methacryloxypropyl silane and experimental silanes with two concentrations (1% and 2.5%): amino, isocyanate, styryl, and acrylate silanes. The silane application method consisted of ...postprin

Effects of Icelandic yogurt consumption and resistance training in healthy untrained older males

Due to the important roles of resistance training and protein consumption in the prevention and treatment of sarcopenia, we assessed the efficacy of post-exercise Icelandic yogurt consumption on lean mass, strength, and skeletal muscle regulatory factors in healthy untrained older males. Thirty healthy untrained older males (age = 68 ± 4 yr) were randomly assigned to Icelandic yogurt (IR; n =15, 18 g of protein) or an iso-energetic placebo (PR; n =15, 0 g protein) immediately following resistance training (3x/week) for eight weeks. Before and after training, lean mass, strength, and skeletal muscle regulatory factors (insulin-like growth factor-1 [IGF-1], transforming growth factor-beta 1 [TGF-β1], growth differentiation factor 15 [GDF15], Activin A, myostatin [MST], and follistatin [FST]) were assessed. There were group x time interactions (p < 0.05) for body mass (IR: Δ 1, PR: Δ 0.7 kg), body mass index (IR: Δ 0.3, PR: Δ 0.2 kg∙m-2), lean mass (IR: Δ 1.3, PR: Δ 0.6 kg), bench press (IR: Δ 4, PR: 2.3 kg), leg press (IR: Δ 4.2, PR: Δ 2.5 kg), IGF-1 (IR: Δ 0.5, Δ PR: 0.1 ng∙mL-1), TGF-β (IR: Δ -0.2, PR: Δ -0.1 ng∙mL-1), GDF15 (IR: Δ -10.3, PR: Δ -4.8 pg∙mL-1), Activin A (IR: Δ -9.8, PR: Δ -2.9 pg∙mL-1), MST (IR: Δ -0.1, PR: Δ -0.04 ng∙mL-1), and FST (IR: Δ 0.09, PR: Δ 0.03 ng∙mL-1), with Icelandic yogurt consumption resulting in greater changes compared to placebo. The addition of Icelandic yogurt consumption to a resistance training program improved lean mass, strength, and altered skeletal muscle regulatory factors in healthy untrained older males compared to placebo. Therefore, Icelandic yogurt as a nutrient-dense source and cost-effective supplement enhances muscular gains mediated by resistance training and consequently may be used as a strategy for the prevention of sarcopenia

Antioxidant Effects of Bioactive Glasses (BGs) and Their Significance in Tissue Engineering Strategies

Elevated levels of oxidative stress are usually observed following injuries, leading to impaired tissue repair due to oxidation-related chronic inflammation. Several attempts have been made to manage this unfavorable situation, and the use of biomaterials with antioxidant activity is showing great promise in tissue engineering and regenerative medicine approaches. Bioactive glasses (BGs) are a versatile group of inorganic substances that exhibit an outstanding regenerative capacity for both hard and soft damaged tissues. The chemical composition of BGs provides a great opportunity for imparting specific biological activities to them. On this point, BGs may easily become antioxidant substances through simple physicochemical modifications. For example, particular antioxidant elements (mostly cerium (Ce)) can be added to the basic composition of the glasses. On the other hand, grafting natural antioxidant substances (e.g., polyphenols) on the BG surface is feasible for making antioxidant substitutes with promising results in vitro. Mesoporous BGs (MBGs) were demonstrated to have unique merits compared with melt-derived BGs since they make it possible to load antioxidants and deliver them to the desired locations. However, there are actually limited in vivo experimental studies on the capability of modified BGs for scavenging free radicals (e.g., reactive oxygen species (ROS)). Therefore, more research is required to determine the actual potential of BGs in decreasing oxidative stress and subsequently improving tissue repair and regeneration. The present work aims to highlight the potential of different types of BGs in modulating oxidative stress and subsequently improving tissue healing

Biomedical waste management by using nanophotocatalysts: The need for new options

Biomedical waste management is getting significant consideration among treatment technologies, since insufficient management can cause danger to medicinal service specialists, patients, and their environmental conditions. The improvement of waste administration protocols, plans, and policies are surveyed, despite setting up training programs on legitimate waste administration for all healthcare service staff. Most biomedical waste substances do not degrade in the environment, and may also not be thoroughly removed through treatment processes. Therefore, the long-lasting persistence of biomedical waste can effectively have adverse impact on wildlife and human beings, as well. Hence, photocatalysis is gaining increasing attention for eradication of pollutants and for improving the safety and clearness of the environment due to its great potential as a green and eco-friendly process. In this regard, nanostructured photocatalysts, in contrast to their regular counterparts, exhibit significant attributes such as non-toxicity, low cost and higher absorption efficiency in a wider range of the solar spectrum, making them the best candidate to employ for photodegradation. Due to these unique properties of nanophotocatalysts for biomedical waste management, we aim to critically evaluate various aspects of these materials in the present review and highlight their importance in healthcare service settings

Investigating Performance of Windscop Installed on Towers in Arid Regions with Using Computational Fluid Dynamics (Case Study: I&amp;M Bank in Nairobi)

ABSTRACT: The windscops are designed mainly to direct the wind and fresh air in the buildings. The windscops are able to gather the outside air and direct it into the building. If we want to make a windscops very effective, it shall be able to rotate on all directions. The windscops performance reaches to its top point when they are designed to direct the air for a big hall like an amusement park, etc. In this paper we paid more of our focus on performance analysis for a type of windscops which are installed on tower peaks. At first, we conducted analysis by means of GAMBIT software regarding the geometric model of windscops and the structure analysis, and then we continued to analyze them by means of FLUENT software regarding their pattern of flow. The results of such analyses were demonstrated as velocity on X&amp;Y directions, and flow pattern

Antidepressants have complex associations with longitudinal depressive burden in bipolar disorder

Aims: Antidepressants are common in bipolar disorder (BD), but controversial due to questionable efficacy/tolerability. We assessed baseline antidepressant use/depression associations in BD. Methods: Stanford BD Clinic outpatients, enrolled during 2000\u20132011, assessed with the Systematic Treatment Enhancement Program for BD (STEP-BD) Affective Disorders Evaluation, were monitored up to two years with the STEP-BD Clinical Monitoring Form while receiving naturalistic expert treatment. Prevalence/correlates of baseline antidepressant use in recovered (euthymic 658 weeks)/depressed patients were assessed. Kaplan\u2013Meier survival analyses assessed times to depressive recurrence/recovery in patients with/without baseline antidepressant use, and Cox Proportional Hazard regression analyses assessed covariate effects. Results: Baseline antidepressant use was significantly (albeit without Bonferroni multiple comparison correction) less among 105 recovered (31.4%) versus 153 depressed (44.4%) patients, and among recovered patients (again without Bonferroni correction), associated with Caucasian race, earlier onset, worse Clinical Global Impression scores, and hastened depressive recurrence (only if mood elevation episodes were not censored), driven by lifetime anxiety disorder, and more (even with Bonferroni correction) bipolar II disorder, lifetime anxiety and eating disorders, and core psychotropics. Baseline antidepressant use among depressed patients was associated with significantly (again without Bonferroni correction) older age, female gender, and more (even with Bonferroni correction) anxiolytics/hypnotics, complex pharmacotherapy, and core psychotropics, but no other unfavorable illness characteristic/current mood symptom, and not time to depressive recovery. Limitations: Tertiary BD clinic referral sample receiving open naturalistic expert treatment. Analyses without/with Bonferroni correction. Conclusions: Additional research is required to assess the complex associations between baseline antidepressant use and longitudinal depressive burden in BD

Differential core pharmacotherapy in bipolar I versus bipolar II disorder and European versus American patients not in a syndromal episode

Assess bipolar disorder subtype and treatment location effects on bipolar disorder core pharmacotherapy. Outpatients not in a syndromal episode referred to the University of Milan and Stanford University Bipolar Disorder Clinics were assessed with SCID for the fourth Edition of the Diagnostic and Statistical Manual of Mood Disorders, and the Systematic Treatment Enhancement Program for Bipolar Disorder Affective Disorders Evaluation, respectively. Prevalence and clinical correlates of antidepressant, antipsychotic, and mood stabilizer use, in aggregate and individually, were compared in bipolar I (BDI) versus II (BDII) patients in Milan/Stanford and in Milan versus Stanford patients, stratified by subtype. Milan/Stanford pooled BDI versus BDII patients significantly more often took antipsychotic (69.8 versus 44.8%), mood stabilizers (68.6 versus 57.7%), and valproate (40.1 versus 17.5%), and less often took antidepressants (23.1 versus 55.6%) and lamotrigine (9.9 versus 25.2%). Milan versus Stanford patients (stratified by bipolar disorder subtype) significantly more often took antipsychotic (BDI and BDII), antidepressants (BDII), and valproate (BDII), and less often took lamotrigine (BDI). Research regarding bipolar disorder core pharmacotherapy relationships with bipolar subtype and treatment location is warranted to enhance clinical management