36 research outputs found
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Exploring Marine and Aeolian Controls on Coastal Foredune Growth Using a Coupled Numerical Model
Coastal landscape change represents aggregated sediment transport gradients from spatially and temporally variable marine and aeolian forces. Numerous tools exist that independently simulate subaqueous and subaerial coastal profile change in response to these physical forces on a range of time scales. In this capacity, coastal foredunes have been treated primarily as wind-driven features. However, there are several marine controls on coastal foredune growth, such as sediment supply and moisture effects on aeolian processes. To improve understanding of interactions across the land-sea interface, here the development of the new Windsurf-coupled numerical modeling framework is presented. Windsurf couples standalone subaqueous and subaerial coastal change models to simulate the co-evolution of the coastal zone in response to both marine and aeolian processes. Windsurf is applied to a progradational, dissipative coastal system in Washington, USA, demonstrating the ability of the model framework to simulate sediment exchanges between the nearshore, beach, and dune for a one-year period. Windsurf simulations generally reproduce observed cycles of seasonal beach progradation and retreat, as well as dune growth, with reasonable skill. Exploratory model simulations are used to further explore the implications of environmental forcing variability on annual-scale coastal profile evolution. The findings of this work support the hypothesis that there are both direct and indirect oceanographic and meteorological controls on coastal foredune progradation, with this new modeling tool providing a new means of exploring complex morphodynamic feedback mechanisms
Direct medical costs of adverse events in Dutch hospitals
Background: Various international studies have shown that a substantial number of patients suffer
from injuries or even die as a result of care delivered in hospitals. The occurrence of injuries among
patients caused by health care management in Dutch hospitals has never been studied
systematically. Therefore, an epidemiological study was initiated to determine the incidence, type
and impact of adverse events among discharged and deceased patients in Dutch hospitals.
Methods/Design: Three stage retrospective patient record review study in 21 hospitals of 8400
patient records of discharged or deceased patients in 2004. The records were reviewed by trained
nurses and physicians between August 2005 and October 2006. In addition to the determination
of presence, the degree of preventability, and causes of adverse events, also location, timing,
classification, and most responsible specialty of the adverse events were measured. Moreover,
patient and admission characteristics and the quality of the patient records were recorded.
Discussion: In this paper we report on the design of the retrospective patient record study on
the occurrence of adverse events in Dutch hospitals. Attention is paid to the strengths and
limitations of the study design. Furthermore, alterations made in the original research protocol in
comparison with former international studies are described in detail.
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Changes in physical activity following a genetic-based internet-delivered personalized intervention: randomized controlled trial (Food4Me)
Background: There is evidence that physical activity (PA) can attenuate the influence of the fat mass- and obesity-associated (FTO) genotype on the risk to develop obesity. However, whether providing personalized information on FTO genotype leads to changes in PA is unknown. Objective: The purpose of this study was to determine if disclosing FTO risk had an impact on change in PA following a 6-month intervention. Methods: The single nucleotide polymorphism (SNP) rs9939609 in the FTO gene was genotyped in 1279 participants of the Food4Me study, a four-arm, Web-based randomized controlled trial (RCT) in 7 European countries on the effects of personalized advice on nutrition and PA. PA was measured objectively using a TracmorD accelerometer and was self-reported using the Baecke questionnaire at baseline and 6 months. Differences in baseline PA variables between risk (AA and AT genotypes) and nonrisk (TT genotype) carriers were tested using multiple linear regression. Impact of FTO risk disclosure on PA change at 6 months was assessed among participants with inadequate PA, by including an interaction term in the model: disclosure (yes/no) × FTO risk (yes/no).
Results: At baseline, data on PA were available for 874 and 405 participants with the risk and nonrisk FTO genotypes, respectively. There were no significant differences in objectively measured or self-reported baseline PA between risk and nonrisk carriers. A total of 807 (72.05%) of the participants out of 1120 in the personalized groups were encouraged to increase PA at baseline. Knowledge of FTO risk had no impact on PA in either risk or nonrisk carriers after the 6-month intervention. Attrition was higher in nonrisk participants for whom genotype was disclosed (P=.01) compared with their at-risk counterparts. Conclusions: No association between baseline PA and FTO risk genotype was observed. There was no added benefit of disclosing FTO risk on changes in PA in this personalized intervention. Further RCT studies are warranted to confirm whether disclosure of nonrisk genetic test results has adverse effects on engagement in behavior change
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Effects of a web-based personalized intervention on physical activity in European adults: a randomized controlled trial
Background: The high prevalence of physical inactivity worldwide calls for innovative and more effective ways to promote physical activity (PA). There are limited objective data on the effectiveness of Web-based personalized feedback on increasing PA in adults.
Objective: It is hypothesized that providing personalized advice based on PA measured objectively alongside diet, phenotype, or genotype information would lead to larger and more sustained changes in PA, compared with nonpersonalized advice.
Methods: A total of 1607 adults in seven European countries were randomized to either a control group (nonpersonalized advice, Level 0, L0) or to one of three personalized groups receiving personalized advice via the Internet based on current PA plus diet (Level 1, L1), PA plus diet and phenotype (Level 2, L2), or PA plus diet, phenotype, and genotype (Level 3, L3). PA was measured for 6 months using triaxial accelerometers, and self-reported using the Baecke questionnaire. Outcomes were objective and self-reported PA after 3 and 6 months.
Results: While 1270 participants (85.81% of 1480 actual starters) completed the 6-month trial, 1233 (83.31%) self-reported PA at both baseline and month 6, but only 730 (49.32%) had sufficient objective PA data at both time points. For the total cohort after 6 months, a greater improvement in self-reported total PA (P=.02) and PA during leisure (nonsport) (P=.03) was observed in personalized groups compared with the control group. For individuals advised to increase PA, we also observed greater improvements in those two self-reported indices (P=.006 and P=.008, respectively) with increased personalization of the advice (L2 and L3 vs L1). However, there were no significant differences in accelerometer results between personalized and control groups, and no significant effect of adding phenotypic or genotypic information to the tailored feedback at month 3 or 6. After 6 months, there were small but significant improvements in the objectively measured physical activity level (P<.05), moderate PA (P<.01), and sedentary time (P<.001) for individuals advised to increase PA, but these changes were similar across all groups.
Conclusions: Different levels of personalization produced similar small changes in objective PA. We found no evidence that personalized advice is more effective than conventional “one size fits all” guidelines to promote changes in PA in our Web-based intervention when PA was measured objectively. Based on self-reports, PA increased to a greater extent with more personalized advice. Thus, it is crucial to measure PA objectively in any PA intervention study
Patient safety in Dutch primary care: a study protocol
<p>Abstract</p> <p>Background</p> <p>Insight into the frequency and seriousness of potentially unsafe situations may be the first step towards improving patient safety. Most patient safety attention has been paid to patient safety in hospitals. However, in many countries, patients receive most of their healthcare in primary care settings. There is little concrete information about patient safety in primary care in the Netherlands. The overall aim of this study was to provide insight into the current patient safety issues in Dutch general practices, out-of-hours primary care centres, general dental practices, midwifery practices, and allied healthcare practices. The objectives of this study are: to determine the frequency, type, impact, and causes of incidents found in the records of primary care patients; to determine the type, impact, and causes of incidents reported by Dutch healthcare professionals; and to provide insight into patient safety management in primary care practices.</p> <p>Design and methods</p> <p>The study consists of three parts: a retrospective patient record study of 1,000 records per practice type was conducted to determine the frequency, type, impact, and causes of incidents found in the records of primary care patients (objective one); a prospective component concerns an incident-reporting study in each of the participating practices, during two successive weeks, to determine the type, impact, and causes of incidents reported by Dutch healthcare professionals (objective two); to provide insight into patient safety management in Dutch primary care practices (objective three), we surveyed organizational and cultural items relating to patient safety. We analysed the incidents found in the retrospective patient record study and the prospective incident-reporting study by type of incident, causes (Eindhoven Classification Model), actual harm (severity-of-outcome domain of the International Taxonomy of Medical Errors in Primary Care), and probability of severe harm or death.</p> <p>Discussion</p> <p>To estimate the frequency of incidents was difficult. Much depended on the accuracy of the patient records and the professionals' consensus about which types of adverse events have to be recognized as incidents.</p
State of the art of aeolian and dune research on the Dutch and Belgian coast
Five years ago, at the previous anniversary of the NCK days, an overview was presented of the state of the art of “Measuring and modelling coastal dune development in the Netherlands” (De Groot et al., 2012). At that moment, new coastal-dune research had sprung up in the Netherlands after a relatively quiet period of about two decades, and the individual research projects were just starting to interconnect. Since then, research has blossomed. A large number of PhD students, postdocs and staff of many institutes are involved, and coastal aeolian processes have become a permanent topic of recent NCK days. Young researchers are meeting a couple of times per year to discuss their work informally, and several PhD theses were defended
Modelling dune erosion, overwash and inundation of barrier islands
Physical model experiments are performed at Deltares to investigate the morphological response of barrier islands on extreme storm events. The experiments included dune erosion, overwash and inundation regimes. Extensive measurement techniques made detailed comparison with numerical models possible. This paper describes the comparison between the physical model results and the numerical morphodynamic model XBeach. It appeared that XBeach simulates the main characteristics in hydro- and morphodynamics at profiles with shallow foreshores, which are characteristic for barrier islands, well. However, the absolute results of especially the overwash experiments still do not agree with the measurements. It is expected that several generic issues regarding small-scale physical model experiments are of influence here. Nevertheless, calibration of the XBeach model seems to be necessary for shallow profiles. Especially the calibration of the wave characteristics on the shallow foreshore, related to the morphodynamics is far from trivial.Hydraulic EngineeringCivil Engineering and Geoscience