5 research outputs found
Phagocytosis of a Model Human Immunodeficiency Virus Target by Human Breast Milk Leukocytes Is Predominantly Granulocyte-Driven When Elicited by Specific Antibody
The effect of IFN-γ and TGF-β in the functional activity of mononuclear cells in the presence of Entamoeba histolytica
Contribution of polymeric immunoglobulin receptor to regulation of intestinal inflammation in dextran sulfate sodium-induced colitis
Fc receptor Îł-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils
ArticleNATURE IMMUNOLOGY. 10(2):214-222 (2009)journal articl
Immunoglobulin A: A next generation of therapeutic antibodies?
Although immunoglobulin (Ig) A is commonly recognized as the most prevalent antibody subclass at mucosal sites with an important role in mucosal defense, its potential as a therapeutic monoclonal antibody is less well known. However, IgA has multifaceted anti-, non- and pro-inflammatory functions that can be exploited for different immunotherapeutical strategies, which will be the focus of this review