2,491 research outputs found
Origin of atomic clusters during ion sputtering
Previous studies have shown that the size distributions of small clusters ( n<=40 n = number of atoms/cluster) generated by sputtering obey an inverse power law with an exponent between -8 and -4. Here we report electron microscopy studies of the size distributions of larger clusters ( n>=500) sputtered by high-energy ion impacts. These new measurements also yield an inverse power law, but one with an exponent of -2 and one independent of sputtering yield, indicating that the large clusters are produced when shock waves, generated by subsurface displacement cascades, ablate the surface
Like-charge attraction through hydrodynamic interaction
We demonstrate that the attractive interaction measured between like-charged
colloidal spheres near a wall can be accounted for by a nonequilibrium
hydrodynamic effect. We present both analytical results and Brownian dynamics
simulations which quantitatively capture the one-wall experiments of Larsen and
Grier (Nature 385, p. 230, 1997).Comment: 10 pages, 4 figure
Association of leukocyte telomere length with perceived physical fatigability
BACKGROUND: Leukocyte telomere length (LTL) is a potential genomic marker of biological aging, but its relation to fatigability, a prognostic indicator of phenotypic aging (e.g., functional decline) is unknown. We hypothesized shorter LTL would predict greater perceived physical fatigability, but that this association would be attenuated by adjusting for chronological age.
METHODS: Two generations of participants (N = 1997; 309 probands, 1688 offspring) were from the Long Life Family Study (age = 73.7 ± 10.4, range 60-108, 54.4 % women), a longitudinal cohort study of aging. LTL was assayed at baseline. Perceived physical fatigability was measured 8.0 ± 1.1 years later using the validated, self-administered 10-item Pittsburgh Fatigability Scale (PFS, 0-50, higher scores = greater fatigability). Generalized estimating equations were generated to model the association between LTL and PFS Physical scores.
RESULTS: Prevalence of greater physical fatigability (PFS scores≥15) was 41.9 %. Using generalized estimating equations, a one kilobase pair shorter LTL was associated with higher PFS Physical scores (β = 1.8, p \u3c .0001), accounting for family structure, and adjusting for field center, follow-up time, sex, and follow-up body mass index, physical activity, and chronic health conditions. When age was included as a covariate, the association was fully attenuated (β = 0.1, p = .78).
CONCLUSION: LTL may provide an alternative method for estimating an individual\u27s lifetime exposure to chronic stressors, but does not appear to provide additional information not captured by chronological age. Further research is needed to characterize the interaction between age, LTL, and perceived fatigability, and develop a method of identifying individuals at risk for deleterious aging
X-ray photoemission study of NiS_{2-x}Se_x (x = 0.0 - 1.2)
Electronic structure of NiS_{2-x}Se_x system has been investigated for
various compositions (x) using x-ray photoemission spectroscopy. An analysis of
the core level as well as the valence band spectra of NiS_2 in conjunction with
many-body cluster calculations provides a quantitative description of the
electronic structure of this compound. With increasing Se content, the on-site
Coulomb correlation strength (U) does not change, while the band width W of the
system increases, driving the system from a covalent insulating state to a
pd-metallic state.Comment: 19 pages, 6 figures, To appear in Phys. Rev. B, 200
Trace mineral concentrations and accretion rates in the empty body and body tissues of growing Fleckvieh (German Simmental) bulls
This research project aimed to generate basic data for
specifying the trace mineral requirements of Fleckvieh (German Simmental)
bulls. Hence, the concentrations of the trace minerals iron (Fe), zinc (Zn), copper (Cu),
and manganese (Mn) in the empty-body and body tissue fractions of growing
Fleckvieh bulls slaughtered at 120–780 kg live weight were determined.
Results were used to calculate trace mineral accretion rates. Fe and Zn
represented the largest shares in the animals' bodies. The Zn accretion
increased, while Mn accretion steadily declined during cattle growth. Fe
accretion attained a maximum at 400 kg live weight. Cu accretion declined
until 600 kg live weight and then increased slightly afterwards. The provided
data may be used to adjust the recommendations with respect to the trace mineral
requirements of growing Fleckvieh bulls.</p
Stochasticity of flow through microcirculation as a regulator of oxygen delivery
<p>Abstract</p> <p>Objective</p> <p>Observations of microcirculation reveal that the blood flow is subject to interruptions and resumptions. Accepting that blood randomly stops and resumes, one can show that the randomness could be a powerful means to match oxygen delivery with oxygen demand.</p> <p>Method</p> <p>The ability of the randomness to regulate oxygen delivery is based on two suppositions: (a) the probability for flow to stop does not depend on the time of uninterrupted flow, thus the number of interruptions of flow follows a Poisson distribution; (b) the probability to resume the flow does not depend on the time for flow being interrupted; meaning that time spent by erythrocytes at rest follows an exponential distribution. Thus the distribution of the time to pass an organ is a compound Poisson distribution. The Laplace transform of the given distribution gives the fraction of oxygen that passes the organ.</p> <p>Result</p> <p>Oxygen delivery to the tissues directly depends on characteristics of the irregularity of the flow through microcirculation.</p> <p>Conclusion</p> <p>By variation of vasomotion activity it is possible to change delivery of oxygen to a tissue by up to 8 times.</p
Spin-Lattice Relaxation in Si Quantum Dots
We consider spin-lattice relaxation processes for electrons trapped in
lateral Si quantum dots in a inversion layer. Such dots are
characterized by strong confinement in the direction perpendicular to the
surface and much weaker confinement in the lateral direction. The spin
relaxation is assumed to be due to the modulation of electron -factor by the
phonon-induced strain, as was shown previously for the shallow donors. The
results clearly indicate that the specific valley structure of the ground
electron state in Si quantum dots causes strong anisotropy for both the
one-phonon and two-phonon spin relaxation rates. In addition, it gives rise to
a partial suppression of the two-phonon relaxation in comparison to the spin
relaxation of donor electrons.Comment: RevTex file, 3 PS figure
Magnetic correlations and quantum criticality in the insulating antiferromagnetic, insulating spin liquid, renormalized Fermi liquid, and metallic antiferromagnetic phases of the Mott system V_2O_3
Magnetic correlations in all four phases of pure and doped vanadium
sesquioxide V_2O_3 have been examined by magnetic thermal neutron scattering.
While the antiferromagnetic insulator can be accounted for by a Heisenberg
localized spin model, the long range order in the antiferromagnetic metal is an
incommensurate spin-density-wave, resulting from a Fermi surface nesting
instability. Spin dynamics in the strongly correlated metal are dominated by
spin fluctuations in the Stoner electron-hole continuum. Furthermore, our
results in metallic V_2O_3 represent an unprecedentedly complete
characterization of the spin fluctuations near a metallic quantum critical
point, and provide quantitative support for the SCR theory for itinerant
antiferromagnets in the small moment limit. Dynamic magnetic correlations for
energy smaller than k_BT in the paramagnetic insulator carry substantial
magnetic spectral weight. However, the correlation length extends only to the
nearest neighbor distance. The phase transition to the antiferromagnetic
insulator introduces a sudden switching of magnetic correlations to a different
spatial periodicity which indicates a sudden change in the underlying spin
Hamiltonian. To describe this phase transition and also the unusual short range
order in the paramagnetic state, it seems necessary to take into account the
orbital degrees of freedom associated with the degenerate d-orbitals at the
Fermi level in V_2O_3.Comment: Postscript file, 24 pages, 26 figures, 2 tables, accepted by Phys.
Rev.
Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain.
Lymphocyte-specific protein-tyrosine kinase (Lck) plays an essential role in T cell receptor (TCR) signaling and T cell development, but its activation mechanism is not fully understood. To explore the possibility that plasma membrane (PM) lipids control TCR signaling activities of Lck, we measured the membrane binding properties of its regulatory Src homology 2 (SH2) and Src homology 3 domains. The Lck SH2 domain binds anionic PM lipids with high affinity but with low specificity. Electrostatic potential calculation, NMR analysis, and mutational studies identified the lipid-binding site of the Lck SH2 domain that includes surface-exposed basic, aromatic, and hydrophobic residues but not the phospho-Tyr binding pocket. Mutation of lipid binding residues greatly reduced the interaction of Lck with the chain in the activated TCR signaling complex and its overall TCR signaling activities. These results suggest that PM lipids, including phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate, modulate interaction of Lck with its binding partners in the TCR signaling complex and its TCR signaling activities in a spatiotemporally specific manner via its SH2 domain.1175Ysciescopu
Hydration interactions: aqueous solvent effects in electric double layers
A model for ionic solutions with an attractive short-range pair interaction
between the ions is presented. The short-range interaction is accounted for by
adding a quadratic non-local term to the Poisson-Boltzmann free energy. The
model is used to study solvent effects in a planar electric double layer. The
counter-ion density is found to increase near the charged surface, as compared
with the Poisson-Boltzmann theory, and to decrease at larger distances. The ion
density profile is studied analytically in the case where the ion distribution
near the plate is dominated only by counter-ions. Further away from the plate
the density distribution can be described using a Poisson-Boltzmann theory with
an effective surface charge that is smaller than the actual one.Comment: 11 Figures in 13 files + LaTex file. 20 pages. Accepted to Phys. Rev.
E. Corrected typos and reference
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