1,153 research outputs found

    Regulation of α 1

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    Image Inpainting Based on Wavelet Decomposition

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    AbstractImage inpainting is an important problem image processing. It is a difficult problem to simultaneously fill-in the texture and structure in regions of missing image information. In order to inpaint the damaged image with both missing the structure and texture information, an image inpainting algorithm based on wavelet decomposition is presented. First the damaged image is decomposed into structure sub-image and texture sub-image using the wavelet transformation. Then, the sub-image with the region of missing information in the structure is reconstructed by Curvature-Driven Diffusions (CDD) algorithm, while the same region in the texture sub-image is filled-in with the improved texture synthesis based on exemplar; Finally, the restored image is given by recombining the structure and texture restored results. A large number of experiments show that the proposed algorithm can quickly and efficiently restore the structure and texture information at the same time, and the visual effects and the Peak Signal to Noise Ratio (PSNR) is better than the similar algorithms

    Na+ Permeation and Block of hERG Potassium Channels

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    The inactivation gating of hERG channels is important for the channel function and drug–channel interaction. Whereas hERG channels are highly selective for K+, we have found that inactivated hERG channels allow Na+ to permeate in the absence of K+. This provides a new way to directly monitor and investigate hERG inactivation. By using whole cell patch clamp method with an internal solution containing 135 mM Na+ and an external solution containing 135 mM NMG+, we recorded a robust Na+ current through hERG channels expressed in HEK 293 cells. Kinetic analyses of the hERG Na+ and K+ currents indicate that the channel experiences at least two states during the inactivation process, an initial fast, less stable state followed by a slow, more stable state. The Na+ current reflects Na+ ions permeating through the fast inactivated state but not through the slow inactivated state or open state. Thus the hERG Na+ current displayed a slow inactivation as the channels travel from the less stable, fast inactivated state into the more stable, slow inactivated state. Removal of fast inactivation by the S631A mutation abolished the Na+ current. Moreover, acceleration of fast inactivation by mutations T623A, F627Y, and S641A did not affect the hERG Na+ current, but greatly diminished the hERG K+ current. We also found that external Na+ potently blocked the hERG outward Na+ current with an IC50 of 3.5 mM. Mutations in the channel pore and S6 regions, such as S624A, F627Y, and S641A, abolished the inhibitory effects of external Na+ on the hERG Na+ current. Na+ permeation and blockade of hERG channels provide novel ways to extend our understanding of the hERG gating mechanisms

    Electromechanical-Mode Coupling Model and Failure Prediction of CFRP under Three-Point Bending

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    Carbon fiber reinforced polymer materials (CFRP) cause CFRP to bend or fail when subjected to external loads or impacts. In the case of static three-point bending, using the conductive properties of the carbon fiber inside the CFRP, the overall damage detection and failure prediction can be carried out by electromagnetic methods. The eddy current coil is used to realize real-time monitoring of damage, and the measured voltage value can be mapped to obtain the load of the sample. This paper conducts theoretical analysis and experimental verification, and obtains the relationship between CFRP stress damage and spatial conductivity change, and proposes a CFRP electromechanical coupling model under quasistatic three-point bending. Combined with the theory of electrically ineffective length, the CFRP three-point bending electromechanical coupling model was revised. Experimental results prove that the revised model can describe the load-conductivity change trend of three-dimensional braided CFRP more accurately, which provides a theoretical basis for monitoring the structural health of CFRP through electromagnetic methods

    The 0++0^{++} and 0−+0^{-+} mass of light-quark hybrid in QCD sum rules

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    We calculate masses of the light-quark hybrid mesons with the quantum number 0++0^{++} and 0−+0^{-+} by using the QCD sum rules. Two kinds of the interpolated currents with the same quantum number are employed. We find that the approximately equal mass is predicted for the 0−+0^{-+} hybrid state from the different current and the different mass is obtained for the 0++0^{++} hybrid state from the different current. The prediction depends on the interaction between the gluon and quarks in the low-lying hybrid mesons. The mixing effect on the mass of the light-quark hybrid meson through Low-energy theorem has been examined too, and it is found that this mixing shifts the mass of hybrid meson and glueball a little.Comment: 11 pages, Latex, 5 ps figure
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