Design of the Magnet System of the Neutron Decay Facility PERC

The PERC (Proton and Electron Radiation Channel) facility is currently under construction at the research reactor FRM II, Garching. It will serve as an intense and clean source of electrons and protons from neutron beta decay for precision studies. It aims to contribute to the determination of the Cabibbo-Kobayashi-Maskawa quark-mixing element $V_{ud}$ from neutron decay data and to search for new physics via new effective couplings. PERC's central component is a 12m long superconducting magnet system. It hosts an 8m long decay region in a uniform field. An additional high-field region selects the phase space of electrons and protons which can reach the detectors and largely improves systematic uncertainties. We discuss the design of the magnet system and the resulting properties of the magnetic field.Comment: Proceedings of the International Workshop on Particle Physics at Neutron Sources PPNS 2018, Grenoble, France, May 24-26, 201

Evaluation of new palladium cages as potential delivery systems for the anticancer drug cisplatin

Self-assembled metallocages are very promising drug-delivery systems among supramolecular complexes. Thus, exo-functionalized Pd2L4 (L=ligand) cages were synthesized and characterized, and the encapsulation of the anticancer drug cisplatin in their cavity has been documented. The antiproliferative effects of the metallocages and their combination with cisplatin were examined in vitro in cancer cell lines, while fluorescence microscopy was used to monitor their uptake. Notably, the hydroxymethyl-functionalized PdII cage encapsulating cisplatin showed improved cytotoxic effect against human ovarian cancer cells compared to free cisplatin. The toxicity of Pd2L4 cages was evaluated for the first time ex vivo in healthy rat-liver tissues using the precision cut-tissue slices technology, demonstrating in some cases scarce effects on liver viability. These results further highlight the potential of self-assembled Pd2L4 cages for biological applications

CCDC 1431656: Experimental Crystal Structure Determination

Related Article: Andrea Schmidt, Viviana Molano, Manuela Hollering, Alexander Pöthig, Angela Casini and Fritz E. Kühn|2016|Chem.-Eur.J.|22|2253|doi:10.1002/chem.201504930,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

CCDC 1431657: Experimental Crystal Structure Determination

Related Article: Andrea Schmidt, Viviana Molano, Manuela Hollering, Alexander Pöthig, Angela Casini and Fritz E. Kühn|2016|Chem.-Eur.J.|22|2253|doi:10.1002/chem.201504930,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Design of the magnet system of the neutron decay facility PERC

The PERC (Proton and Electron Radiation Channel) facility is currently under construction at the research reactor FRM II, Garching. It will serve as an intense and clean source of electrons and protons from neutron beta decay for precision studies. It aims to contribute to the determination of the Cabibbo-Kobayashi-Maskawa quark-mixing element Vud from neutron decay data and to search for new physics via new effective couplings. PERC's central component is a 12 m long superconducting magnet system. It hosts an 8 m long decay region in a uniform field. An additional high-field region selects the phase space of electrons and protons which can reach the detectors and largely improves systematic uncertainties. We discuss the design of the magnet system and the resulting properties of the magnetic field