Body talk

First published in International Therapist (Issue 36, October 2011), the membership journal of the Federation of Holistic TherapistsA critical evaluation of the spa, beauty and massage industry's approach towards promoting body esteem. Suggestions for practitioners and managers to build supportive body based environments and communication practises are give

Metastasis and circulating tumor cells

Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor. In a patient with metastatic disease, circulating tumor cells (CTCs) can be found in venous blood. These circulating tumor cells are part of the metastatic cascade. Clinical studies have shown that these cells can be used to predict treatment response and their presence is strongly associated with poor survival prospects. Enumeration and characterization of CTCs is important as this can help clinicians make more informed decisions when choosing or evaluating treatment. CTC counts are being included in an increasing number of studies and thus are becoming a bigger part of disease diagnosis and therapy management. We present an overview of the most prominent CTC enumeration and characterization methods and discuss the assumptions made \ud about the CTC phenotype. Extensive CTC characterization of for example the DNA, RNA and antigen expression may lead to more understanding of the metastatic process

Deep HST V- and I-Band Observations of Two Globular Clusters in the Halo of M31

We present deep (V ~= 27) V- and I-band stellar photometry of G302 and G312, two globular star clusters in the halo of M31. These data were obtained using the Hubble Space Telescope's Wide Field/Planetary Camera 2. We find iron abundances of [Fe/H] = -1.85 +/- 0.12 for G302 and [Fe/H] = -0.56 +/- 0.03 for G312, consistent with spectroscopic measurements. The color-magnitude diagrams for each cluster show no evidence for an intermediate-aged population of stars, or a second parameter effect in the morphology of the horizontal branch. G302 shows no evidence for a color gradient but the inner regions of G312 are bluer than the outer regions. G312 shows no evidence of ellipticity or an extended halo of unbound stars. G302 has a projected ellipticity of 0.195 +/- 0.012 with the projected major axis oriented towards the center of M31. G302 also shows evidence of an extended asymmetric stellar halo extending to at least twice the fitted Michie-King tidal radius. The amount of mass beyond the tidal radius of G302 is consistent with the stellar escape rates which have been predicted by N-body simulations of globular clusters in the Galactic tidal field.Comment: 29 pages, 21 Postscript figures, uses aaspp4.sty, to be published in the October 1997 A