24 research outputs found

    Where Did The Moon Come From?

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    The current standard theory of the origin of the Moon is that the Earth was hit by a giant impactor the size of Mars causing ejection of iron poor impactor mantle debris that coalesced to form the Moon. But where did this Mars-sized impactor come from? Isotopic evidence suggests that it came from 1AU radius in the solar nebula and computer simulations are consistent with it approaching Earth on a zero-energy parabolic trajectory. But how could such a large object form in the disk of planetesimals at 1AU without colliding with the Earth early-on before having a chance to grow large or before its or the Earth's iron core had formed? We propose that the giant impactor could have formed in a stable orbit among debris at the Earth's Lagrange point L4L_4 (or L5L_5). We show such a configuration is stable, even for a Mars-sized impactor. It could grow gradually by accretion at L4L_4 (or L5L_5), but eventually gravitational interactions with other growing planetesimals could kick it out into a chaotic creeping orbit which we show would likely cause it to hit the Earth on a zero-energy parabolic trajectory. This paper argues that this scenario is possible and should be further studied.Comment: 64 pages, 27 figures, accepted for publication in A

    Histology of the vaginal wall in women with pelvic organ prolapse: a literature review.

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    INTRODUCTION AND HYPOTHESIS: The pathophysiology of pelvic organ prolapse (POP) is incompletely understood. The purpose of this study is to describe the current knowledge about histology of the vaginal wall and its possible involvement in the pathogenesis of pelvic organ prolapse. METHODS: Eligible studies were selected through a MEDLINE search covering January 1986 to December 2012. The research was limited to English-language publications. RESULTS: Investigations of changes in the vaginal tissue that occur in women with genital prolapse are currently still limited and produced contrary results. The heterogeneity of the patients and the control groups in terms of age, parity and hormonal status, of the localization of biopsies and the histological methods as well as the lack of validation of the quantification procedures do not allow clear and definitive conclusions to be drawn. CONCLUSIONS: This review shows that current knowledge of the histological changes observed in women with POP are inconclusive and relatively limited. More studies are needed in this specific field to better understand the mechanisms that lead to POP
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