THE LEADERSHIP DEVELOPMENT OF FRATERNITY AND SORORITY LIFE MEMBERS

This study examines the relationship of perceived leadership development opportunities in fraternities and sororities. The study\u27s main goal was to determine if there was a discrepancy in perceived leadership development opportunities in general members, versus executive board members, whether there was a difference in findings for fraternity members versus sorority members, and suggestions on how to improve opportunities on a university level for students in Fraternity and Sorority Life going forward. The study was distributed to all social Fraternity and Sorority members at Rowan University that were in their respective organization for at least one year prior to the survey. The findings suggest that perceived opportunities are on average high and both fraternity and sorority members reported close to or exceeded the mean. Opportunities for executive board members were also perceived to be slightly higher for sorority members versus their general membership, while fraternity members reported more of equal opportunity

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

We purified poly(A)+ mRNA from the spleen and lymph nodes at designated times after infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 mice. The steady-state levels of IL-2, IFN-gamma, IL-4, and IL-1 beta mRNA were determined using Northern hybridizations. IL-2 mRNA levels in the infected organs of BALB/c and C57BL/6 mice were comparable after infection, but IFN-gamma and IL-4 mRNA levels were reciprocally expressed. Levels of IFN-gamma mRNA in C57BL/6 draining nodes and spleen were significantly greater than in BALB/c mice except at 4 and 6 wk of infection, when splenic IFN-gamma mRNA levels were transiently comparable. In contrast, IL-4 mRNA was apparent only in BALB/c and not in C57BL/6 nodes and spleen. Tissue levels of IL-1 beta mRNA were 10-20-fold greater in BALB/c mice. BALB/c mice were pretreated with GK1.5 mAb, a manipulation that promotes healing of subsequent infection by transiently depleting L3T4+ cells. At 8 wk of infection, by which time lymphoid organs were repopulated with L3T4+ cells, GK1.5-pretreated BALB/c mice produced IFN-gamma, but not IL-4 message. Serum levels of IgE were markedly elevated in infected BALB/c, but not in infected C57BL/6 or GK1.5-pretreated BALB/c mice, consistent with in vivo biologic activity of IL-4 in nonhealing mice. Treatment of infected BALB/c mice with neutralizing anti-IL-4 antibody abolished the elevation of serum IgE and significantly attenuated the progression of disease as assessed by size and ulceration of the lesion, and by reduction in the number of tissue parasites. Both protective and deleterious responses to Leishmania infection have previously been shown to be L3T4+ cell dependent. Our findings are consistent with the differential expansion of protective, IFN-gamma-producing Th1 cells in healing mice, and the expansion of deleterious, IL-4-producing Th2 cells in nonhealing mice. The inverse relationship of IFN-gamma and IL-4 gene expression during leishmaniasis may underlie the divergence of cellular and humoral immunity that occurs during chronic infection with Leishmania and possibly other intracellular parasites

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes. The immune response has been further characterized by a lack of IFN-gamma mRNA, but increased IL-4 mRNA in lymphoid tissues, and striking elevation of serum IgE. Treatment of infected BALB/c mice with rIFN-gamma at doses shown to be beneficial in other protozoan infections was insufficient to ameliorate L. major infection. In contrast, neutralization of IL-4 by six weekly injections of mAb 11B11 led to attenuation of disease in 100% of animals, and complete cure in 85%. Resolution of disease required the presence of T cells, and recovered mice remained resistant to reinfection at 12 wk. This immunity was adoptively transferable and was dependent on both CD4+ and CD8+ cells. Although administration of anti-IL-4 was associated with fourfold increase in IFN-gamma mRNA in lymph node cells draining the lesion, the coadministration of neutralizing R4 6A2 anti-IFN-gamma mAb had no effect on resistance to disease. This was in marked contrast to resolution of disease in both resistant C57BL/6- and GK1.5-pretreated BALB/c mice that was abrogated by in vivo treatment with anti-IFN-gamma. These data suggest a novel mechanism of cellular immunity established by interference with the development of Th2 cells during infection

Impact of Economic Trends and Disparities on South Carolina Children’s Health and Well-being: An Analysis of the 2016 KIDS COUNT Profile

There are many approaches to conceptualizing and measuring the well-being of children. These indices vary considerably depending on the goal of the scale. However, all of these indices share similar characteristics in that they are multi-dimensional and take into account the complexity of children’s lives. One of the best known of these measures is the Annie E. Casey Foundation’s national KIDS COUNT Data Book (http://www.aecf.org/resources/the-2016-kids-countdata-book/). Each year since 1990 the Casey Foundation has released the KIDS COUNT Data Book. This data provides key information about dimensions of child well-being in the following areas: health, education, economic well-being and family and community. During the past 10 years the KIDS COUNT project has provided a website that has data of more than 100 state level measures of child well-being, and also provides county level data for each state

Body Image Implications on Mental and Health Well-Being

https://scholarworks.moreheadstate.edu/student_scholarship_posters/1092/thumbnail.jp