Cleidocranial dysplasia-dental disorder treatment and audiology diagnosis

A review of numerous case reports was made, in order to demonstrate the possibilities for treatment of dental disorders in patients with Cleidocranial dysplasia (CCD). In this paper, our own report, including a diagnosis of the effect on the auditory system, is presented. In addition to the triad of CCD symptoms that include hypoplastic or aplastic clavicles, impacted and supernumerary teeth, delayed closure of fontanelles and cranial sutures, impairment of the hearing system resulting in conductive hearing loss also occurs. Our own report is based on the case of a 12-year-old CCD patient, in whom Cone Beam Computed Tomography (CBCT) revealed the presence of 12 supernumerary teeth. Furthermore, a clinical examination pointed to the presence of retained deciduous teeth and a delayed eruption of permanent teeth. Orthodontic-surgical procedures were implemented, in accordance with the literature. During the course of the orthodontic treatment, a decrease in auditory sensitivity was observed, for which reason hearing tests were also performed. Conductive hearing loss was detected. As such, it is important to remember that in such cases, auditory check-ups need to be performed between the many surgical and orthodontic interventions, which usually last a few years

Effects of Temperature on the FT NIR Raman Spectra of Fish Skin Collagen

The development of regenerative medicine turns attention toward native collagen as a biocompatible material. Particularly interesting is fish skin collagen, which is relatively easy to extract comparing mammalian tissues and free of some pathogens that are dangerous to humans. The paper presents results of IR Raman spectroscopy studies of silver carp (Hypophthalmichthys molitrix) skin collagen. As collagen properties result from its structure and conformation, both sensitive to temperature, FT NIR Raman spectroscopy is an excellent tool to characterize the molecular structure of fish skin collagen, particularly in temperature range typical for the manufacturing processes of biomedical products. Therefore, the Raman spectra were recorded in a temperature range of 300 to 403 K. The analysis of Raman spectra of prepared collagen films, particularly in the range of the bands related to amide I and amide III entities, showed a high content of α-helix and α-helix type molecular organization in fish skin collagen. Additionally, the secondary structure of the studied fish skin collagen is stable up to ~358 K. Heating to 403 K leads to irreversible changes in the molecular structure of fish skin collagen. It was found that the Raman spectrum of fish skin collagen preheated in this manner becomes similar to the spectrum of the collagen obtained from bovine Achilles tendon, whose secondary structure does not change up to 403 K

Effect of Low Frequency Magnetic Field (LFMF) on the Germination of Seeds and Selected Useful Characters of Onion (<i>Allium cepa </i>L.)

Magnetic fields (MF) have been reported widely as pre-sowing seeds treatment to increase their vigour, seedling growth and the plants’ yield. Although it has been shown that MF could affect seed germination and the seedling root growth, still their further effect on plant’s life has been found to be inconsistent, especially under field conditions. Commercial seed lots of onion (Allium cepa L.) of the cultivars ‘Octavia’ and ‘Eureka’ were soaked for 12 hours in the distilled water at 20 °C. Next, they were exposed to low frequency magnetic field (LFMF) of magnetic induction B=20 mT, for 10, 30 and 60 minutes. The LFMF was generated using a standard medical device for magnetostimulation VIOFOR JPS. Next, the seeds were evaluated for germination and received bulbs were analysed for the selected useful characters including the root length, maximal diameters, dry matter and quercetin content. For the LFMF treatment of 60 minutes, for the cultivars ‘Octavia’ and ‘Eureka’, the energy of germination increased from 75.8% and 65% (control) to 88.3% and 87.5%, respectively. For the LFMF treatment of 60 minutes, the germination capacity, for the same cultivars, increased from 85% and 76.3% (control) to 92% and 90%, respectively, treated for 60 minutes with LFMF onion seeds had longer seedlings than the ones from the control seeds. These values, for both cultivars, increased from 5.3 cm and 4.2 cm (control) to 8.4 cm and 5.7 cm, respectively. LFMF used for 60 minutes on the ‘Octavia’ onion seeds, increased their emergences in the field and length of the roots on the bulbs. LFMF used had no effect on the dry matter of bulbs grown out from the seeds when exposing them for 10 and 30 minutes. However, when exposing them for 60 minutes, LFMF decreased the dry matter and increased the amount of quercetin

Cleidocranial dysplasia-dental disorder treatment and audiology diagnosis

A review of numerous case reports was made, in order to demonstrate the possibilities for treatment of dental disorders in patients with Cleidocranial dysplasia (CCD). In this paper, our own report, including a diagnosis of the effect on the auditory system, is presented. In addition to the triad of CCD symptoms that include hypoplastic or aplastic clavicles, impacted and supernumerary teeth, delayed closure of fontanelles and cranial sutures, impairment of the hearing system resulting in conductive hearing loss also occurs. Our own report is based on the case of a 12-year-old CCD patient, in whom Cone Beam Computed Tomography (CBCT) revealed the presence of 12 supernumerary teeth. Furthermore, a clinical examination pointed to the presence of retained deciduous teeth and a delayed eruption of permanent teeth. Orthodontic-surgical procedures were implemented, in accordance with the literature. During the course of the orthodontic treatment, a decrease in auditory sensitivity was observed, for which reason hearing tests were also performed. Conductive hearing loss was detected. As such, it is important to remember that in such cases, auditory check-ups need to be performed between the many surgical and orthodontic interventions, which usually last a few years

Cleidocranial dysplasia-dental disorder treatment and audiology diagnosis

A review of numerous case reports was made, in order to demonstrate the possibilities for treatment of dental disorders in patients with Cleidocranial dysplasia (CCD). In this paper, our own report, including a diagnosis of the effect on the auditory system, is presented. In addition to the triad of CCD symptoms that include hypoplastic or aplastic clavicles, impacted and supernumerary teeth, delayed closure of fontanelles and cranial sutures, impairment of the hearing system resulting in conductive hearing loss also occurs. Our own report is based on the case of a 12-year-old CCD patient, in whom Cone Beam Computed Tomography (CBCT) revealed the presence of 12 supernumerary teeth. Furthermore, a clinical examination pointed to the presence of retained deciduous teeth and a delayed eruption of permanent teeth. Orthodontic-surgical procedures were implemented, in accordance with the literature. During the course of the orthodontic treatment, a decrease in auditory sensitivity was observed, for which reason hearing tests were also performed. Conductive hearing loss was detected. As such, it is important to remember that in such cases, auditory check-ups need to be performed between the many surgical and orthodontic interventions, which usually last a few years

The impact of regular diving on the condition of the middle ear

ObjectivesIt is generally held that exposure to both high-pressure and long-lasting contact with water makes diving a potentially hazardous sports activity as far as the ears are concerned. There is a number of research investigating the condition of the middle ear in a short period following diving; however, the knowledge regarding the long-term effects of regularly repeated diving remains limited.Material and methodsThe aim of this study is to evaluate the function of the middle ear after a diving season in a group of 31 adults diving regularly (1–17 years) by means of the following methods: 1) interview, 2) otoscopy, 3) pure tone audiometry, 4) classic tympanometry, and 5) wideband tympanometry.ResultsPeriodic problems with pressure equalization in the middle ear were observed in 12 individuals (38.7%). In all the analyzed cases, the authors found a normal condition of the external auditory canal and the tympanic membrane in otoscopy, normal hearing in pure tone audiometry, curve type A, and normal gradient in both classic and wideband tympanometry. Conclusions: Safe diving (according to safety precautions) does not have any long-term negative effects on the condition of the middle ear. However, these observations should be verified in a larger group of divers

Can Assessment of Rheological Properties of Whole Blood and Plasma Be Useful in the Diagnosis of Tinnitus? A Pilot Study

Tinnitus is a sensation of ringing in the ears in the absence of any physical source in the environment. Between 9&ndash;35% of adults experience some form of tinnitus. Common causes of tinnitus include noise, head injury, ototoxic substances, as well as disorders of blood and blood vessels. Vascular causes include: head&mdash;neck tumours, turbulent blood flow, problems with blood supply and inner ear cell damage. The aspect of rheology in terms of tinnitus has not been described yet. In the present study, which comprised 12 patients aged 30 to 74 years presenting with tinnitus, rheological properties of whole blood and plasma were assessed. All the subjects underwent audiological and neurological evaluation. The Quemada model was used to describe the variability of red blood cell shape, as well as their tendency to form aggregates. On the basis of the experimental study, statistically different results of haemorheological measurements were observed in the evaluated group in comparison to a reference group