Predictors of dropout in face-to-face and internet-based cognitive-behavioral therapy for bulimia nervosa in a randomized controlled trial

Objective: We sought to identify predictors and moderators of failure to engage (i.e., pretreatment attrition) and dropout in both Internet-based and traditional face-to-face cognitive-behavioral therapy (CBT) for bulimia nervosa. We also sought to determine if Internet-based treatment reduced failure to engage and dropout. Method: Participants (N = 191, 98% female) were randomized to Internet-based CBT (CBT4BN) or traditional face-to-face group CBT (CBTF2F). Sociodemographics, clinical history, eating disorder severity, comorbid psychopathology, health status and quality of life, personality and temperament, and treatment-related factors were investigated as predictors. Results: Failure to engage was associated with lower perceived treatment credibility and expectancy (odds ratio [OR] = 0.91, 95% CI: 0.82, 0.97) and body mass index (BMI) (OR = 1.10; 95% CI: 1.03, 1.18). Dropout was predicted by not having a college degree (hazard ratio [HR] = 0.55; 95% CI: 0.37, 0.81), novelty seeking (HR = 1.02; 95% CI: 1.01, 1.03), previous CBT experience (HR = 1.77; 95% CI: 1.16, 2.71), and randomization to the individual's nonpreferred treatment format (HR = 1.95, 95% CI: 1.28, 2.96). Discussion: Those most at risk of failure to engage had a higher BMI and perceived treatment as less credible and less likely to succeed. Dropout was associated with less education, higher novelty seeking, previous CBT experience, and a mismatch between preferred and assigned treatment. Contrary to expectations, Internet-based CBT did not reduce failure to engage or dropout

Novel methodology for predicting the critical salt concentration of bubble coalescence inhibition

Bubble coalescence in some salt solutions can be inhibited if the salt concentration reaches a critical concentration Ccr. There are three models available for Ccr in the literature, but they fail to predict Ccr correctly. The first two models employ the van der Waals attraction power laws to establish Ccr from the discriminant of quadratic or cubic polynomials. To improve the two models, the third model uses the same momentum balance equation of the previous models but different intermolecular force generated by water hydration with exponential decaying. The third prediction for Ccr requires the experimental input for film rupture thickness and is incomplete. We show further in this paper that the third model is incorrect. We propose a novel methodology for determining C cr which resolves the mathematical uncertainties in modeling C cr and can explicitly predict it from any relevant intermolecular forces. The methodology is based on the discovery that Ccr occurs at the local maximum of the balance equation for the capillary pressure, disjoining pressure, and pressure of the Gibbs-Marangoni stress. The novel generic approach is successfully validated using nonlinear equations for complicated disjoining pressure

7th Drug hypersensitivity meeting: part two

No abstract availabl

Metallo-supramolecular architectures based on terpyridine metal complexes

+214hlm.;24c

Metallo-supramolecular graft copolymers : a novel approach for polymer-analogous reactions

Bis(2,2:6,2-terpyrid-4-yl) diethylene glycol was synthesized as a monomer unit and further utilized for polymerization with FeCl2 in order to form water-soluble coordination polymers. Viscosity measurements and film-forming properties indicate the formation of linear coordination polymers or larger ring structures. The terpyridine/iron(II) complexes are stable up to temperatures of 210 °C, but can be uncomplexed by the addition of an excess of a strong competitive ligand (HEDTA) under mild conditions

Combination of Orthogonal Supramolecular Interactions in Polymeric Architectures

Supramolecular polymers represent a highly interesting approach towards new smart materials. A recent strategy includes the combination of different orthogonal non-covalent binding sites within one polymer system. Different functionalities can be introduced in a highly defined way by controlled self-assembly processes. This feature article presents highlights in the supramolecular polymer chemistry of multiple hydrogen-bonding, metal complexation (especially of bi- and terpyridines) and host–guest interactions as well as recent advances in combining these interactions in novel polymers

Supramolecular terpolymers for covalent and non-covalent cross-linking

Terpolymers with terpyridine moiety can be crosslinked covalently or non-covalently. The terpolymer with self reparing ability can be useful for smart materials. A terpolymer was prepd. consisting of Me methacrylate, glycidyl methacrylate, and terpyridinyloxypropyl methacrylate and can be reversibly crosslinked by FeCl2. [on SciFinder (R)

Metallo-supramolecular graft copolymers : a novel approach for polymer-analogous reactions

Bis(2,2:6,2-terpyrid-4-yl) diethylene glycol was synthesized as a monomer unit and further utilized for polymerization with FeCl2 in order to form water-soluble coordination polymers. Viscosity measurements and film-forming properties indicate the formation of linear coordination polymers or larger ring structures. The terpyridine/iron(II) complexes are stable up to temperatures of 210 °C, but can be uncomplexed by the addition of an excess of a strong competitive ligand (HEDTA) under mild conditions