22 research outputs found
Моделирование динамических процессов в ядерных реакторах в среде MATLAB/Simulink
- Author
- Publication venue
- Publication date
- 01/01/2010
- Field of study
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
- Author
- Aaltonen M
- Abdur Rahman M
- Abell T
- Abide W. Jr
- Acheatel R
- Achiri P
- Acon J
- Adams T
- Affinito S
- Agarwal S
- Aggarwal K
- Aggarwal R
- Ahlström P
- Ahmad A
- Ahmed M
- Aillon C
- Airaksinen A
- Ait-sadi R
- Akers J
- Al-jumaily J
- Albers C
- Albert M
- Alberti A
- Alexander T
- Alford C
- Algotsson L
- Allen T
- Allworth M
- Almond E
- Aloisi A
- Alternburg C
- Alton M
- Amin J
- Amundson A
- Andersen K
- Andersen M
- Anderson E
- Anderson G
- Anderson R
- Anderson T
- Andersson H
- Andersson L
- Andreo J
- Andres C
- Andresen D
- Andrews G
- Andrews L
- Andrews R
- Andrioli V
- Angermann Ce
- Annas T
- Ansell V
- Antonio-drabek C
- Antonishen D
- Antonishen M
- Anuschek V
- Appel Kf
- Appel S
- Appleyard D
- Archer A
- Armitage J
- Armstrong L
- Armstrong M
- Arnesson K
- Arnold M
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- Arp H
- Asbill B
- Ashbrook-raby C
- Ashton L
- Assarsson E
- Audet K
- Augenbraun C
- Aung HNIN THANDA
- Auscher S
- Ausner J
- Aviles R
- Awasty V
- Axelsson U
- Ayers S
- Ayub H
- Babar G
- Babington G
- Backlund M
- Badal B
- Baggiore C
- Baghiana S
- Bai H
- Bai J
- Baigent C
- Baillargeon G
- Bakbak A
- Baker S
- Baldin Mg
- Baldini E
- Baldwin E
- Ballantyne C
- Baltic A
- Banerjee S
- Bang Hansen M
- Banks K
- Bansilal S
- Barkley-daughtry S
- Barnes D
- Barnes E
- Barnett S
- Baroni Claudio
- Barry S
- Barter P
- Bartolomei Mecatti B
- Barton I
- Barton J
- Baré C
- Bashton D
- Basler M
- Bastani L
- Basvi P
- Batchlett K
- Bateman S
- Battistelli E
- Baty J
- Bauersachs J
- Bauman A
- Bavendiek U
- Baxter A
- Bayly G
- Bays H
- Beasley T
- Beck P
- Beck S
- Becker P
- Beebe S
- Been M
- Begg R
- Behm K
- Beilker J
- Beißner S
- Bekfani T
- Belanger B
- Belew K
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- Bellamy C
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- Börjesson M
- Cai J
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- CARIDAD HERNANDEZ JOSE MANUEL
- Carlos S
- Carlsen H
- Carlsson M
- Caro H
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- Casey MAEVE ANN
- Casolo G
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- Chen Weipeng
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- Childs A
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- Christensen A
- Christensen B
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- Chu Y
- Chun-furlong D
- Chung K
- Chung R
- Ciampanelli E
- Ciuica S
- Clark A
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- Claxton E. Jr
- Clayton-evans L
- Clemens L
- Clements M
- Clemmensen P
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- Cleverley P
- Cluley C
- Coates G
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- Crivellari ADAM MARIA ROMANO
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- Davey P
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- Dawkins Hughes S
- Dayanandan R
- De Boer I
- De Burca B
- De Donno O
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- De Lorenzi E
- De Matteis C
- De Servi S
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- Dechert M
- Defosse C
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- Delgado T
- Delozier A
- Delucca P
- Demets D
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- Dengler T
- Desai N
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- Deslongchamp F
- Desousa C
- Destefano R
- Dettmer M
- Dhaliwal M
- Di Biase M
- DI BUONO Antonio
- Di Donato A
- Di Matteo C
- Di Pasquale G
- Di Ruocco M
- Diao Q
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- Dickinson RONALD CELESTE
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- Zhao L
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- Zhu Wangqin
- Zhu X
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- Ziefle S
- Zilz N
- Zineldine A
- Zlatewa R
- Zoghbi J
- Zong C
- Zong D
- Zong X
- Zuchelkowski A
- Zulauf N
- Ågårdh A
- Öner A
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
BACKGROUND:
Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes.
METHODS:
We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization.
RESULTS:
During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events.
CONCLUSIONS:
Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)
Stromatolite branching in the Neoproterozoic of the Centralian Superbasin, Australia: an investigation into sedimentary and microbial control of stromatolite morphology
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Digitale Radiografie in der Untersuchung von arbeits- und umweltbedingten Lungen- und Pleuraerkrankungen
- Author
- Publication venue
- 'Georg Thieme Verlag KG'
- Publication date
- 01/01/2009
- Field of study
Diagnostik und Begutachtung asbestbedingter Berufskrankheiten
- Author
- Publication venue
- 'Georg Thieme Verlag KG'
- Publication date
- 01/01/2011
- Field of study
Thermodynamics of Condensed Phases: Formula Unit Volume, Vm, and the Determination of the Number of Formula Units, Z, in a Crystallographic Unit Cell
- Author
- Barin I.
- Bernstein J.
- Binnewies M.
- Chase M. W.
- Donnay J. D. H.
- Glasser L.
- Glasser L.
- Glasser L.
- Glasser L.
- Glasser L.
- Glasser L.
- Glasser L.
- Glasser L.
- Hagler A. T.
- Hahn T.
- Hellwege K. H.
- Hofmann D. W. M.
- Jenkins H. D. B.
- Jenkins H. D. B.
- Jenkins H. D. B.
- Jenkins H. D. B.
- Jenkins H. D. B.
- Jenkins H. D. B.
- Julian M. M.
- Kempster C. J. E.
- Kumar V.
- Lide D. R.
- Meng Q.-B.
- Neumann H.
- Ohrendorf F. W.
- Preiss U.
- Preiss U.
- Reddy R. R.
- Saxena S. K.
- Smrcok L.
- Verma A. S.
- Verma A. S.
- Verma A. S.
- Wagman D. D.
- Yoder C. H.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- 01/01/2011
- Field of study
Formula unit (or molecular) volume, Vm, is related to many thermodynamic and physical properties of materials, so that knowledge of Vm is useful in prediction of such properties for known and even hypothetical materials. The symbol Z represents the number of formula units in a crystallographic unit cell; Z thus permits calculation of Vm from the unit-cell volume. Unfortunately, Z is sometimes omitted from published crystal constants (for obscure reasons).We discuss methods for evaluation of Z and Vm, and some of the complications in the assessment of Z. We show how entropy, lattice energy, and bulk isothermal compressibility (a thermoelastic property) are calculated using thermodynamic correlations, with the chalcopyrite CuAlS2 as an example
Dimensional parameters of columnar stromatolites as a result of stromatolite ecosystem evolution
- Author
- E. R. Shpunt
- F. Ya. Vlasov
- G. I. Kirichenko
- H. J. Hofmann
- H. J. Hofmann
- I. G. Shapovalova
- I. K. Korolyuk
- I. K. Korolyuk
- I. N. Krylov
- I. N. Krylov
- I. N. Krylov
- I. N. Krylov
- I. N. Krylov
- I. N. Krylov
- I. N. Krylov
- J. A. Donaldson
- J. Bertrand-Sarfati
- J. Bertrand-Sarfati
- J. Bertrand-Sarfati
- K. Grey
- K. Grey
- K. N. Konyushkov
- M. A. Semikhatov
- M. A. Semikhatov
- M. A. Semikhatov
- M. A. Semikhatov
- M. A. Semikhatov
- M. A. Semikhatov
- M. A. Semikhatov
- M. A. Semikhatov
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- M. E. Raaben
- N. N. Yakovlev
- N. P. Golovanov
- N. P. Golovanov
- N. P. Golovanov
- N. P. Golovanov
- P. E. Cloud
- P. F. Hoffman
- R. Cao
- R. V. Butin
- S. V. Nuzhnov
- T. A. Dol’nik
- T. A. Dol’nik
- T. A. Dol’nik
- V. A. Komar
- V. A. Komar
- V. A. Komar
- V. N. Sergeev
- V. N. Sergeev
- V. V. Khomentovskii
- V. V. Lyubtsov
- V. V. Makarikhin
- V. V. Makarikhin
- V. Yu. Shenfil’
- V. Yu. Shenfil’
- W. V. Preiss
- W. V. Preiss
- W. V. Preiss
- W. V. Preiss
- Yu. Liang
- Yu. Liang
- Yu. Xing
- Publication venue
- 'Pleiades Publishing Ltd'
- Publication date
- Field of study
An Algorithm for Acute Wrist Trauma
- Author
- APPLE JS
- BELL MS
- BELSOLE RJ
- BELSOLE RJ
- BRØNDUM V
- C. F. LARSEN
- CRISTIANI G
- ENGEL J
- FRAHM R
- FRIEDMAN L
- G. WIENHOLTZ
- GILULA LA
- GUNDRY CR
- HARDY DC
- HEALY C
- HERBERT TJ
- HOFMANN-PREISS K
- HOLBROOK JL
- IMAEDA T
- J. ABRAHAMSEN
- J. BEYER
- KURSUNOGLU-BRAHME S
- KURSUNOGLU-BRAHME S
- LARSEN CF
- LARSEN CF
- LINN MR
- LINSCHEID RL
- MANASTER BJ
- MINO DE
- MINO DE
- NAKAMURA R
- PIN PG
- PITTMAN CC
- POSNER M
- QUINN SF
- REINUS WR
- SANDERS WE
- SCHMIDT C
- SCHMITT VON R
- SOWA DT
- SPACE TC
- TALEISNIK J
- V. BRØNDUM
- WECHSLER RJ
- WEEKS PM
- WILSON AJ
- WILSON AW
- ZLATKIN MB
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
The G516T CYP2B6 Germline Polymorphism Affects the Risk of Acute Myeloid Leukemia and Is Associated with Specific Chromosomal Abnormalities
- Author
- A Wiktor
- Aggeliki Daraki
- B Deschler
- BS Preiss
- C Justenhoven
- C Xu
- CA Jaffe
- Constantina Sambani
- D Grimwade
- D Grimwade
- DA Arber
- EA Copelan
- EL Code
- F Marchesi
- FS Cabrera
- Gabriel E. Pantelias
- H Jinno
- H Kim
- H Wanng
- HW Chung
- J Pedersen-Bjergaard
- J Pedersen-Bjergaard
- J Wang
- J Yuan
- JS Miles
- JW Vardiman
- JY Cho
- K Mrozek
- K Mrózek
- K Mrózek
- Kalliopi N. Manola
- L Zhang
- L Zhang
- LM Dong
- M Aydin-Sayitoglu
- M Berköz
- M Hiratsuka
- M Turpeinen
- M Turpeinen
- M Yanada
- MG Belitsky GA Yakubovskaya
- MH Hofmann
- MT Baker
- MT Smith
- MT Smith
- MT Voso
- N Bozina
- Network Cancer Genome Atlas Research
- P Bolufer
- P Roy
- Panagoula Kollia
- Paraskevi Diamantopoulou
- RB Walter
- RL Hodgson E Rose
- RM Jacob
- S Ekins
- S Guan
- S Kayser
- S Majumdar
- S Miksys
- SM Hoffman
- Sophia Zachaki
- SY Kim
- T Lang
- T Shimada
- Tao Cai
- TC Liu
- Theodora Koromila
- TK Eyada
- UM Zanger
- V Lamba
- V Powers
- Vasiliki Aleporou
- WS Stillman
- WS Stillman
- ZH Yuan
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Topological edge states of interacting photon pairs emulated in a topolectrical circuit
- Author
- A Blanco-Redondo
- AB Khanikaev
- AM Marques
- BA Bernevig
- CH Lee
- CL Kane
- CL Kane
- DC Mattis
- EI Rosenthal
- F Schindler
- F Schindler
- G Salerno
- I Carusotto
- J Ningyuan
- J-L Tambasco
- K Winkler
- L Lu
- L Lu
- M Aidelsburger
- M Atala
- M Bello
- M Di Liberto
- M Di Liberto
- M Hafezi
- M Hafezi
- M Serra-Garcia
- M Valiente
- MA Gorlach
- MA Gorlach
- MA Gorlach
- MC Rechtsman
- ME Tai
- MZ Hasan
- N Strohmaier
- NR Cooper
- O Dutta
- P Roushan
- P Roushan
- PM Preiss
- RA Pinto
- S Barik
- S Imhof
- S Longhi
- S Mittal
- S Mittal
- S Mukherjee
- S Ryu
- SD Huber
- T Helbig
- T Hofmann
- T Liu
- T Ozawa
- VV Albert
- WA Benalcazar
- WA Benalcazar
- WP Su
- X Qin
- Y Hadad
- Y Ke
- Y Li
- Y Wang
- Y Wang
- Y Ye
- Z Wang
- Z Yang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study