Ruthenium nanoparticles supported on hydroxyapatite as an efficient and recyclable catalyst for cis-dihydroxylation and oxidative cleavage of alkenes

Impregnation of hydroxyapatite with colloidal ruthenium results in the formation of a catalyst that effects cis-dihydroxylation and oxidative cleavage of alkenes to their respective cis-1,2-diols and carbonyl products in good to excellent yields (see scheme). The supported ruthenium catalyst can be easily recycled and reused for consecutive reaction runs without significant deterioration of the catalytic activities. R1, R2 = H, alkyl, aryl.postprin

Reconstructive surgery for burn patients

Reconstructive surgery in burn patients is difficult because of the intense scarring and the necessity to carry out multiple operative procedures for different reconstructive needs in a single patient. The primary aim of the surgeon is to prevent hypertrophic scar by early wound closure, and proper postburn treatment using a combination of silicone gel, splinting, and pressure therapy. Reconstructive procedures should be deferred until the wounds have matured. Accurate preoperative assessment and appreciation of the true tissue deficiency, appropriate application of different reconstructive options, and the establishment of the priorities of reconstruction in relation to individual requirements are essential for a successful outcome. In general, functional needs have to be met before attending to aesthetic concerns and priority should be given to restore active before passive function. Different reconstructive options using direct closure, skin grafts, flaps, free tissue transfer, and tissue expansion are discussed.published_or_final_versio

Endothelial Progenitors Exist within the Kidney and Lung Mesenchyme

The renal endothelium has been debated as arising from resident hemangioblast precursors that transdifferentiate from the nephrogenic mesenchyme (vasculogenesis) and/or from invading vessels (angiogenesis). While the Foxd1-positive renal cortical stroma has been shown to differentiate into cells that support the vasculature in the kidney (including vascular smooth muscle and pericytes) it has not been considered as a source of endothelial cell progenitors. In addition, it is unclear if Foxd1-positive mesenchymal cells in other organs such as the lung have the potential to form endothelium. This study examines the potential for Foxd1-positive cells of the kidney and lung to give rise to endothelial progenitors. We utilized immunofluorescence (IF) and fluorescence-activated cell sorting (FACS) to co-label Foxd1-expressing cells (including permanently lineage-tagged cells) with endothelial markers in embryonic and postnatal mice. We also cultured FACsorted Foxd1-positive cells, performed in vitro endothelial cell tubulogenesis assays and examined for endocytosis of acetylated low-density lipoprotein (Ac-LDL), a functional assay for endothelial cells. Immunofluorescence and FACS revealed that a subset of Foxd1-positive cells from kidney and lung co-expressed endothelial cell markers throughout embryogenesis. In vitro, cultured embryonic Foxd1-positive cells were able to differentiate into tubular networks that expressed endothelial cell markers and were able to endocytose Ac-LDL. IF and FACS in both the kidney and lung revealed that lineage-tagged Foxd1-positive cells gave rise to a significant portion of the endothelium in postnatal mice. In the kidney, the stromal-derived cells gave rise to a portion of the peritubular capillary endothelium, but not of the glomerular or large vessel endothelium. These findings reveal the heterogeneity of endothelial cell lineages; moreover, Foxd1-positive mesenchymal cells of the developing kidney and lung are a source of endothelial progenitors that are likely critical to patterning the vasculature. © 2013 Sims-Lucas et al

Analysis of recurrence after surgical treatment of advanced laryngeal carcinoma

The pattern of recurrences after surgical treatment of 276 patients with stage T3 and T4 laryngeal carcinoma was reviewed. Nodal recurrence was the commonest site and occurred mainly in patients with supraglottic and transglottic carcinoma. Distant metastasis was the second commonest site of recurrence, and the most distant metastases developed without locoregional recurrence. Local recurrence alone was uncommon in patients treated with primary surgery.published_or_final_versio

Assessment of regional systolic and diastolic impairment of left ventricular function: a study with tissue doppler imaging on right ventricular pacing

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Reconstruction after craniofacial trauma

Management of craniofacial trauma has became a sophisticated branch of reconstructive surgery in the last 20 years. New operative techniques and advanced technologies have evolved to allow much better treatment results to be achieved. The general principles of diagnosis and management of craniofacial trauma are discussed. The approach to individual fractures is also highlighted.published_or_final_versio

Assessment of regional systolic and diastolic impairment on left ventricular function: a study with tissue Doppler imaging on right ventricular pacing

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Ring-type electric current sensor based on ring-shaped magnetoelectric laminate of epoxy-bonded Tb₀.₃Dy₀.₇Fe₁.₉₂ short-fiber/NdFeB magnet magnetostrictive composite and Pb(Zr, Ti)O₃ piezoelectric ceramic

Author name used in this publication: S. L. Ho2009-2010 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Improved management of the donor site of free radial forearm flap

Conference Theme: Challenges to specialists in the 21st centurypublished_or_final_versio