48 research outputs found
Design, Development and Evaluation of Biochemistry Virtual Laboratory for Blended Learning
This paper examines students’ reflection on the design and development of a prototype biochemistry virtual laboratory (vLab) at the University of Hong Kong. Second year students from the MBBS programme were divided into two groups. One group (non-vLab) took part in the original didactic lecture while the other group (vLab) joined in the trial blended virtual lab learning session. The learning outcomes were evaluated by a post-lab knowledge comprehension quiz and the class performances were analyzed. In addition, students’ perceptions toward blended vLab learning experience were evaluated by questionnaires. The group with the vLab experience achieved higher quiz results. However, their evaluation and feedback with regard to the vLab learning experience were rather critical, which provided valuable insights for further improvements on the instructional design.published_or_final_versio
Potential use of Niti implant for intra-articular fracture of phalax
Session - New Developments in Orthopaedic Implant Materialspublished_or_final_versio
Development of a Prototype Biochemistry Virtual Laboratory: reflections on the Instructional Design
This paper describes and critically evaluates the instructional design process for the development of a prototype biochemistry virtual laboratory for teaching and learning for medical students. The designing strategy was essentially based on the ADDIE model. However, many innovative ideas and practical tips are discussed in this paper to illustrate the importance of case specific adaptations. For example, factors such as intended learning outcomes, learning pedagogy and learner’s reactions will be considered. In particular, our research findings emphasize the importance of students’ feedback of virtual lab design during the evaluation stage, which provides valuable insights for the instructional designers.published_or_final_versio
Effects of qigong exercise on upper limb lymphedema and blood flow in survivors of breast cancer: A pilot study
postprin
Family conflict and lower morning cortisol in adolescents and adults: modulation of puberty
published_or_final_versio
Identification of novel interactions between viral envelop proteins and activating receptor family of natural killer cells
Colloque Scientific du Réseau International des Instituts Pasteur, Hong Kong, November 2006
Preferential type1-1 cytokine gene expressions in peripheral T-cell lymphomas
In this study, we have investigated whether a pattern of cytokine gene expression can be found in non-Hodgkin's peripheral T-cell lymphoma (PTCL). By using RNase protection assays and RT-PCR, we have systematically studied IL1α, IL1β, IL1-Ra, IL2, IL4, IL5, IL6, IL9, IL10, IL12p35, IL12p40, IL13, IL14, IL15, IFNγ, IFNβ, TNFα, TNFβ, LTβ, and TGFβ1, TGFβ2 and TGFβ3. Twenty-two cases of PTCL inclusive of three nasal NK-cell lymphomas were selected for the study; three cases of reactive lymphoproliferation were included for comparison. Results show that IFNγ gene expression (key Type 1 cytokine) was frequently detected [18/22 (82 per cent)]. In contrast, IL4 (key Type 2 cytokine) was only detected in 4/22 (18 per cent) of cases (weaker than IFNγ in three cases). This distinction was also found at the protein level by immunohistochemistry. In addition, TNFβ and TNFα (strongly expressed by Type 1 cells) were almost complimentarily detected [4/19 (21 per cent)] and 12/19 (63 per cent), respectively). In contrast, neither IL5 nor IL13 (strongly expressed by Type 2 cells) were detected at all. However, 14/22 cases expressed IL10, another Type 2 cytokine, which suggests that the autoregulatory feedback loop is stimulated. Compared to the tumour types, the cytokine profiles in the reactive lymphoproliferative types also resembled a Type 1-like pattern but was less striking. The overall result suggested a preferential expression of certain cytokines, and these cytokines may play an important role in pathophysiologic progression in these T-cell disorders. Copyright (C) 1999 John Wiley and Sons, Ltd.link_to_subscribed_fulltex