17 research outputs found
Designing CALL for learning Chinese characters
Despite the enormity of its quantity, printed or written forms of Chinese characters are composed from a limited number of common components. For example, the characters for pond( ), lake( ), stream( ), river ( ), sea( ) and ocean( ) all contain a component in common, a three-dot component representing water. When this clue is explicitly highlighted to students, the learning of Chinese characters can be greatly enhanced. Using a computer to help students to develop this kind of structural awareness about language learning has not yet been thoroughly examined. This paper reports on the design of CALL software based on a pedagogic method which helps students to develop the higher order skills to analyse and categorise Chinese characters by using components. The result of the classroom experiment has shown supportive evidence on the feasibility and the need of integrating the software with an affective and contextual way of teaching Chinese characters.postprin
The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic and macrophage infiltration, microvessel density and survival in patients with primary operable breast cancer
The significance of the inter-relationship between tumour and host local/systemic inflammatory responses in primary operable invasive breast cancer is limited. The inter-relationship between the systemic inflammatory response (pre-operative white cell count, C-reactive protein and albumin concentrations), standard clinicopathological factors, tumour T-lymphocytic (CD4+ and CD8+) and macrophage (CD68+) infiltration, proliferative (Ki-67) index and microvessel density (CD34+) was examined using immunohistochemistry and slide-counting techniques, and their prognostic values were examined in 168 patients with potentially curative resection of early-stage invasive breast cancer. Increased tumour grade and proliferative activity were associated with greater tumour T-lymphocyte (P<0.05) and macrophage (P<0.05) infiltration and microvessel density (P<0.01). The median follow-up of survivors was 72 months. During this period, 31 patients died; 18 died of their cancer. On univariate analysis, increased lymph-node involvement (P<0.01), negative hormonal receptor (P<0.10), lower albumin concentrations (P<0.01), increased tumour proliferation (P<0.05), increased tumour microvessel density (P<0.05), the extent of locoregional control (P<0.0001) and limited systemic treatment (Pless than or equal to0.01) were associated with cancer-specific survival. On multivariate analysis of these significant covariates, albumin (HR 4.77, 95% CI 1.35–16.85, P=0.015), locoregional treatment (HR 3.64, 95% CI 1.04–12.72, P=0.043) and systemic treatment (HR 2.29, 95% CI 1.23–4.27, P=0.009) were significant independent predictors of cancer-specific survival. Among tumour-based inflammatory factors, only tumour microvessel density (P<0.05) was independently associated with poorer cancer-specific survival. The host inflammatory responses are closely associated with poor tumour differentiation, proliferation and malignant disease progression in breast cancer
Development of the Cantonese speech intelligibility index
A Speech Intelligibility Index (SII) for the sentences in the Cantonese version of the Hearing In Noise Test (CHINT) was derived using conventional procedures described previously in studies such as Studebaker and Sherbecoe [J. Speech Hear. Res. 34, 427-438 (1991)]. Two studies were conducted to determine the signal-to-noise ratios and high- and low-pass filtering conditions that should be used and to measure speech intelligibility in these conditions. Normal hearing subjects listened to the sentences presented in speech-spectrum shaped noise. Compared to other English speech assessment materials such as the English Hearing In Noise Test [Nilsson et al., J. Acoust. Soc. Am. 95, 1085-1099 (1994)], the frequency importance function of the CHINT suggests that low-frequency information is more important for Cantonese speech understanding. The difference in frequency importance weight in Chinese, compared to English, was attributed to the redundancy of test material, tonal nature of the Cantonese language, or a combination of these factors. © 2007 Acoustical Society of America.link_to_subscribed_fulltex
Risk Management in Large Physical Infrastructure Investments: The Context of Seaport Infrastructure Development and Investment
The growth of developing countries depends very much on having adequate physical infrastructure to support economic development. As a strategic response, many physical infrastructure investments like seaports are being privatised and highly purpose built. This paper investigates the merits of viable seaport infrastructure investment, typically ‘lumpy’ and requiring large capital expenditure and long payback period. A key feature of such an infrastructure investment is to structure a defensible risk management strategy to deal with uncertainties. This risk management strategy can provide responsive alternatives to new opportunities. Singapore's Jurong Port is the case study. The original risk management strategy is analysed in 1996, and deploys risk simulation for scenario planning in conjunction with constraint optimisation. This original risk management strategy finds that it is more defensible to configure Jurong Port, and a seaport in general, into the maritime industrial and logistics park (MILP) instead of the higher-margin and purpose-built container terminal strategy, which is inherently volatile (ie uncertain or risky). The planned scenarios and their projections, under the original risk management strategy are then compared with the consequential developments in reality. The results highlight that the sustained viability of Jurong Port in 2004 is attributed to that risk management strategy, originally developed in 1996. Maritime Economics & Logistics (2006) 8, 140–168. doi:10.1057/palgrave.mel.9100153