264 research outputs found

    Re-calibration of SDF/SXDS Photometric Catalogs of Suprime-Cam with SDSS Data Release 8

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    We present photometric recalibration of the Subaru Deep Field (SDF) and Subaru/XMM-Newton Deep Survey (SXDS). Recently, Yamanoi et al. (2012) suggested the existence of a discrepancy between the SDF and SXDS catalogs. We have used the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8) catalog and compared stars in common between SDF/SXDS and SDSS. We confirmed that there exists a 0.12 mag offset in B-band between the SDF and SXDS catalogs. Moreover, we found that significant zero point offsets in i-band (~ 0.10 mag) and z-band (~ 0.14 mag) need to be introduced to the SDF/SXDS catalogs to make it consistent with the SDSS catalog. We report the measured zero point offsets of five filter bands of SDF/SXDS catalogs. We studied the potential cause of these offsets, but the origins are yet to be understood.Comment: 36 pages, 19 figures(128 EPS files), PASJ accepte

    Perineuronal Sulfated Proteoglycans, Cell Surface Glycoproteins and Dark Neurons in the Cingulate Cortex of Newborn and Adult Rats

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    Many neurons in the adult rat cingulate cortex possess perineuronal sulfated proteoglycans detectable with cationic iron colloid and aldehyde fuchsin, or cell surface glycoproteins reactive to lectin Vicia villosa or soybean agglutinin. The perineuronal sulfated proteoglycans develop three to four weeks after birth. The cell surface glycoproteins develop at earlier stage or two to three weeks after birth. Dark or active neurons begin to appear three to four weeks after birth. These findings indicate that the brain matures after birth or during weaning period.</p

    Perineuronal Sulfated Proteoglycans in the Adult Rat Brain: Histochemical and Electron Microscopic Studies

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    Neurons of cerebellar nuclei in the rat brain had a marked surface coat which was stained with cationic iron colloid or aldehyde fuchsin. Neurons with a similar surface coat were also noted in the retrosplenial cortex. The surface coat was stained doubly with cationic iron colloid and aldehyde fuchsin. Digestion with hyaluronidase eliminated the stainability of the surface coat to both agents. Combined digestion with chondroitinase ABC, heparitinase and keratanase eliminated the cationic iron colloid staining but did not interfere with the aldehyde fuchsin staining. Electron microscopy of ultrathin sections revealed that the iron particles were deposited in the perineuronal tissue spaces. These findings indicate that the surface coat consists of sulfated proteoglycans which occupy, as the extracellular matrix, the perineuronal tissue spaces. Many neurons in the retrosplenial cortex were labeled with lectin Vicia villosa agglutinin. Double staining revealed that these lectin-labeled neurons are usually reactive to cationic iron colloid. Few neurons in the cerebellar nuclei were labeled with lectin V. villosa agglutinin.</p

    Psychological factors that promote behavior modification by obese patients

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    <p>Abstract</p> <p>Background</p> <p>The weight-loss effect of team medical care in which counseling is provided by clinical psychologists was investigated in an university hospital obesity (OB) clinic. Nutritional and exercise therapy were also studied. In our previous study, we conducted a randomized, controlled trial with obese patients and confirmed that subjects who received counseling lost significantly more weight than those in a non-counseling group. The purpose of this study was to identify the psychological characteristics assessed by ego states that promote behavior modification by obese patients.</p> <p>Methods</p> <p>147 obese patients (116 females, 31 males; mean age: 45.9 ± 15.4 years) participated in a 6-month weight-loss program in our OB clinic. Their psychosocial characteristics were assessed using the Tokyo University Egogram (TEG) before and after intervention. The Wilcoxon signed rank test was used to compare weight and psychological factors before and after intervention. Multiple regression analysis was used to identify factors affecting weight loss.</p> <p>Results</p> <p>Overall, 101 subjects (68.7%) completed the program, and their data was analyzed. The subjects mean weight loss was 6.2 ± 7.3 kg (<it>Z </it>= 7.72, <it>p </it>< 0.01), and their mean BMI decreased by 2.4 ± 2.7 kg/m<sup>2 </sup>(<it>Z </it>= 7.65, <it>p </it>< 0.01). Significant differences were observed for the Adult (A) ego state (0.68 ± 3.56, <it>Z </it>= 1.95, <it>p </it>< 0.05) and the Free Child (FC) ego state (0.59 ± 2.74, <it>Z </it>= 2.46, <it>p </it>< 0.01). The pre-FC ego state had a significant effect on weight loss (β = 0.33, <it>p </it>< 0.01), and a tendency for changes in the A ego state scores to affect weight loss (β = - 0.20, <it>p </it>= 0.06) was observed.</p> <p>Conclusion</p> <p>This study of a 6-month weight-loss program that included counseling by clinical psychologists confirmed that the A ego state of obese patients, which is related to their self-monitoring skill, and the FC ego state of them, which is related to their autonomy, were increased. Furthermore, the negative aspects of the FC ego state related to optimistic and instinctive characteristics inhibited the behavior modification, while the A ego state represented objective self-monitoring skills that may have contributed to weight loss.</p

    Pulmonary venous occlusion and death in pulmonary arterial hypertension: survival analyses using radiographic surrogates

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    BACKGROUND: Recent studies find that a considerable number of patients with pulmonary arterial hypertension (PAH) develop fibrous obstruction of the pulmonary veins. Such obstruction more commonly accompanies connective tissue disorder (CTD)-associated PAH than idiopathic PAH. However, few researchers have gauged the risk of death involving obstruction of the pulmonary veins. METHODS: Thirty-seven patients with PAH were enrolled (18 patients, idiopathic PAH; 19 patients, CTD-associated PAH). The patients were 49 ± 18 years and had a World Health Organization functional class of 3.2 ± 0.6. Thickening of the interlobular septa, centrilobular ground-glass attenuation, and mediastinal adenopathy were surrogates for obstruction of the pulmonary veins, and were detected by a 16-row multidetector computed tomography scanner. RESULTS: The follow-up period was 714 ± 552 days. Fifteen deaths occurred. Thickening of the interlobular septa, centrilobular ground-glass attenuation, and mediastinal adenopathy were found in 37.8%, 24.3%, and 16.2% of patients, respectively. Cox proportional hazard analysis revealed an increased risk of death with each radiographic surrogate (mediastinal adenopathy: p < 0.0001, hazard ratio = 13.9; thickening of interlobular septa: p < 0.001, hazard ratio = 12.0; ground-glass attenuation: p = 0.02, hazard ratio = 3.7). The statistical significance of these relationships was independent of the cause of PAH and plasma concentration of brain natriuretic peptide. CONCLUSIONS: The results of this study imply that obstruction of the pulmonary veins is associated with an increased risk of death in patients with PAH

    Strange filamentary structures ("fireballs") around a merger galaxy in the Coma cluster of galaxies

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    We found an unusual complex of narrow blue filaments, bright blue knots, and H-alpha emitting filaments and clouds, which morphologically resembled a complex of ``fireballs,'' extending up to 80 kpc south from an E+A galaxy RB199 in the Coma cluster. The galaxy has a highly disturbed morphology indicative of a galaxy--galaxy merger remnant. The narrow blue filaments extend in straight shapes toward the south from the galaxy, and several bright blue knots are located at the southern ends of the filaments. The Rc band absolute magnitudes, half light radii and estimated masses of the bright knots are -12 - -13 mag, 200 - 300 pc and 10^6-7 Msolar, respectively. Long, narrow H-alpha emitting filaments are connected at the south edge of the knots. The average color of the fireballs is B - Rc = 0.5, which is bluer than RB199 (B - R = 0.99), suggesting that most of the stars in the fireballs were formed within several times 10^8 yr. The narrow blue filaments exhibit almost no H-alpha emission. Strong H-alpha and UV emission appear in the bright knots. These characteristics indicate that star formation recently ceased in the blue filaments and now continues in the bright knots. The gas stripped by some mechanism from the disk of RB199 may be traveling in the intergalactic space, forming stars left along its trajectory. The most plausible fireball formation mechanism is ram pressure stripping by high-speed collision between the galaxy and the hot intra-cluster medium. The fireballs may be a snapshot of diffuse intra-cluster population formation, or halo star population formation in a cluster galaxy.Comment: 13 pages, 14 figures, submitted to Ap

    Awareness of Complications of Dental Treatment in Patients Treated with Drugs Affecting the Immune System : A Nationwide Questionnaire Survey of Dental Practitioners in Japan

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    The aim of this study was to investigate the awareness and experience, among dental practitioners, of adverse events resulting from dental treatment of patients undergoing therapy with drugs that affect the immune system [angiogenesis inhibitors, biological agents, immunosuppressants, and disease-modifying anti-rheumatic drugs (DMARDs)]. For this purpose, a nationwide questionnaire survey was conducted. Questionnaires were sent to 2,050 dentists, of which 206 (10.1%) were completed and returned. The results showed that most dentists were aware of complications associated with dental treatment of patients treated with drugs that affect the immune system, and about half had actually experienced such complications. Delayed wound healing, osteonecrosis of the jaw (ONJ), and postoperative infections were reported. Whereas approximately 50% of dentists did not discontinue the drugs during dental treatment, about 18% did. During temporary drug discontinuation, some patients experienced aggravation of the primary disease, such as worsening of rheumatism, growth of tumors, and rejection reactions of transplanted organs. As for medical cooperation, only less than half of the dentists were asked for oral hygiene management by a physician prior to starting the drug treatment. Prospective studies are needed because evidence for dental treatments in patients treated with these drugs remains limited

    Prevention of Disuse Muscle Atrophy by Dietary Ingestion of 8-Prenylnaringenin in Denervated Mice

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    Flavonoids have attracted considerable attention in relation to their effects upon health. 8-Prenylnaringenin (8-PN) is found in the common hop (Humulus lupulus) and assumed to be responsible for the health impact of beer consumption. We wanted to clarify the effects of prenylation on the physiological functions of dietary flavonoids by comparing the effects of 8-PN with that of intact naringenin in the prevention of disuse muscle atrophy using a model of denervation in mice. Consumption of 8-PN (but not naringenin) prevented loss of weight in the gastrocnemius muscle further supported by the lack of induction of the protein content of a key ubiquitin ligase involved in muscle atrophy, atrogin-1, and by the activation of Akt phosphorylation. 8-PN content in the gastrocnemius muscle was tenfold higher than that of naringenin. These results suggested that, compared with naringenin, 8-PN was effectively concentrated into skeletal muscle to exert its preventive effects upon disuse muscle atrophy. It is likely that prenylation generates novel functions for 8-PN by enhancing its accumulation into muscle tissue through dietary intake
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