POLLUTION BY PERSISTENT TOXIC SUBSTANCES IN VIETNAM : A REVIEW OF TWO DECADE MONITORING STUDIES

Joint Research on Environmental Science and Technology for the Eart

Arsenic contamination in groundwater and its toxic effects on human health in Vietnam

Joint Research on Environmental Science and Technology for the Eart

PERSISTENT ORGANOCHLORINE RESIDUES IN HUMAN BREAST MILK FROM VIETNAM : CONTAMINATION, ACCUMULATION KINETICS AND RISK ASSESSMENT

Joint Research on Environmental Science and Technology for the Eart

Contamination by PCDDs, PCDFs and coplanar PCBs in open dumping sites in Vietnam-levels, patterns and toxic implications

Joint Research on Environmental Science and Technology for the Eart

Arsenic contamination in groundwater and residents from Ha Nam and Ha Tay Provinces of Red River Delta, Vietnam

Joint Research on Environmental Science and Technology for the Eart

Contamination by arsenic and other trace elements in drinking water and residents in Vietnam

Joint Research on Environmental Science and Technology for the Eart

PERSISTENT ORGANIC POLLUTANTS(POPs) IN VIETNAMESE ENVIRONMENT-A REVIEW OF CONTAMINATION, FATE AND TOXIC POTENTIAL

Joint Research on Environmental Science and Technology for the Eart

OVERVIEW OF ARSENIC CONTAMINATION IN GROUNDWATER AND HUMAN HEALTH RISK IN VIETNAM

Joint Research on Environmental Science and Technology for the Eart

Studies on conjugation of Spirogyra using monoclonal culture

We succeeded in inducing conjugation of Spirogyracastanacea by incubating algal filaments on agar plate. Conjugation could be induced using clone culture. The scalariform conjugation was generally observed, while lateral conjugation was rarely. When two filaments formed scalariform conjugation, all cells of one filament behaved as male and those of other filament did as female. Very rarely, however, zygospores were formed in both of pair filaments. The surface of conjugation tube was stained with fluorescently labeled-lectins, such as Bandeiraea (Griffonia) simplicifolia lectin (BSL-I) and jacalin. BSL-I strongly stained the conjugation tubes, while weakly did the cell surface of female gamete first and then that of male gamete. Jacalin stained mainly the conjugation tubes. Addition of jacalin inhibited the formation of papilla, suggesting some important role of jacalin-binding material at the initial step of formation of the conjugation tubes

Individual Variations in Inorganic Arsenic Metabolism Associated with AS3MT Genetic Polymorphisms

Individual variations in inorganic arsenic metabolism may influence the toxic effects. Arsenic (+3 oxidation state) methyltransferase (AS3MT) that can catalyze the transfer of a methyl group from S-adenosyl-l-methionine (AdoMet) to trivalent arsenical, may play a role in arsenic metabolism in humans. Since the genetic polymorphisms of AS3MT gene may be associated with the susceptibility to inorganic arsenic toxicity, relationships of several single nucleotide polymorphisms (SNPs) in AS3MT with inorganic arsenic metabolism have been investigated. Here, we summarize our recent findings and other previous studies on the inorganic arsenic metabolism and AS3MT genetic polymorphisms in humans. Results of genotype dependent differences in arsenic metabolism for most of SNPs in AS3MT were Inconsistent throughout the studies. Nevertheless, two SNPs, AS3MT 12390 (rs3740393) and 14458 (rs11191439) were consistently related to arsenic methylation regardless of the populations examined for the analysis. Thus, these SNPs may be useful indicators to predict the arsenic metabolism via methylation pathways