Effects of image lag on real-time target tracking in radiotherapy

There is a concern that image lag may reduce accuracy of real-time target tracking in radiotherapy. This study was performed to investigate influence of image lag on the accuracy of target tracking in radiotherapy. Fluoroscopic image: were obtained using a direct type of dynamic flat-panel detector (FPD) system under conditions of target tracking during radiotherapy. The images continued to be read out after X-irradiations and cutoff, and image lag properties in the system were then determined. Subsequently, a tungsten materials plate with a precision edge was mounted on to a motor control device, which provided a constant velocity. The plate was moved into the center of the detector at movement rate of 1 and 20 mm/s, covering lung tumor movement of normal breathing, and MTF and profile curves were measured on the edges covering and uncovering the detector. A lung tumor with blurred edge due to image lag was simulated using the results and then superimposed on breathing chest radiographs of a patient. The moving target with and without image lag was traced using a template-matching technique. In the results, the target could be traced within a margin for error ii external radiotherapy. The results indicated that there was no effect of image lag on target tracking in usual breathing speed in a radiotherapy situation. Further studies are required to investigate influence by the other factors, such a: exposure dose, target size and shape, imaging rate, and thickness of a patient\u27s body. © 2010 SPIE

Feasibility study on EEG driven robotic system to realize efficient stroke rehabilitation

We aim to develop an efficient robotic system for stroke rehabilitation, in which a robotic arm moves the hemiplegic upper limb when the patient tries to move it. In order to achieve this goal we have considered a method to detect the patient's intended motion using EEG (Electroencephalogram), and have designed a rehabilitation robot based on a Redundant Drive Method. In this paper, we propose an EEG driven rehabilitation robot system and present initial results evaluating the feasibility of the proposed system

Crossover of Rate-Limiting Process in Plasma Gel Growth by Contact with Source of Gelator

Plasma is regarded as a solution of precursor polymers specifically transformed to gel-forming polymers by a reaction with initiators. We developed a theory for the gel growth dynamics of plasma induced by contact with a source of gelators that are yielded by the initiation. In developing the theory, we combined the Ginzburg–Landau type dynamics with the gelator diffusion dynamics expressed by the moving boundary picture. The theory predicts the crossover of the rate-limiting process in the time course of the thickness of the gel layer X from the energy-limited process expressed by X∼t to the diffusion-limited process expressed by X∼t, where t is the time elapsed from when the plasma comes into contact with the source of gelators. A demonstration experiment was performed by placing a tissue factor coating plate as the initiator in plasma. Log–log plot of X vs. t showed a crossover as predicted by the theory, and the parameters characterizing plasma were determined

Crossover of Rate-Limiting Process in Plasma Gel Growth by Contact with Source of Gelator

Plasma is regarded as a solution of precursor polymers specifically transformed to gel-forming polymers by a reaction with initiators. We developed a theory for the gel growth dynamics of plasma induced by contact with a source of gelators that are yielded by the initiation. In developing the theory, we combined the Ginzburg–Landau type dynamics with the gelator diffusion dynamics expressed by the moving boundary picture. The theory predicts the crossover of the rate-limiting process in the time course of the thickness of the gel layer X from the energy-limited process expressed by X∼t to the diffusion-limited process expressed by X∼t, where t is the time elapsed from when the plasma comes into contact with the source of gelators. A demonstration experiment was performed by placing a tissue factor coating plate as the initiator in plasma. Log–log plot of X vs. t showed a crossover as predicted by the theory, and the parameters characterizing plasma were determined

Utilization of kinematical redundancy of a rehabilitation robot to produce compliant motions under limitation on actuator performance

This paper addresses the mechanical structure and control method of a redundant drive robot (RDR) to produce compliant motions, and show how the design parameters of the RDR can effect the produced motions and the mechanical and performance limitations of the actuators of the RDR. The structure and control method of the RDR can have been proper to produce compliant motions, but the effect of the design parameters of the RDR to the mechanical and performance limitations have not been clear. Therefore, the feasibility of producing compliant motions in the case of the prototype of the RDR is confirmed by conducting simulations and experiments, and then the design parameters of the RDR to the mechanical and performance limitations are verified by conducting simulations

Investigation on effect of image lag in fluoroscopic images obtained with a dynamic flat-panel detector (FPD) on accuracy of target tracking in radiotherapy

金沢大学医薬保健研究域保健学系Real-time tumor tracking in external radiotherapy can be achieved by diagnostic (kV) X-ray imaging with a dynamic flat-panel detector (FPD). The purpose of this study was to address image lag in target tracking and its influence on the accuracy of tumor tracking. Fluoroscopic images were obtained using a direct type of dynamic FPD. Image lag properties were measured without test devices according to IEC 62220-1. Modulation transfer function (MTF) and profile curves were measured on the edges of a moving tungsten plate at movement rate of 10 and 20 mm/s, covering lung tumor movement of normal breathing. A lung tumor and metal sphere with blurred edge due to image lag was simulated using the results and then superimposed on breathing chest radiographs of a patient. The moving target with and without image lag was traced using a template-matching technique. In the results, the image lag for the first frame after X-ray cutoff was 2.0% and decreased to less than 0.1% in the fifth frame. In the measurement of profile curves on the edges of static and moving tungsten material plates, the effect of image lag was seen as blurred edges of the plate. The blurred edges of a moving target were indicated as reduction of MTF. However, the target could be traced within an error of ± 5 mm. The results indicated that there was no effect of image lag on target tracking in usual breathing speed in a radiotherapy situation

Cognitive Decline with Pupil Constriction Independent of Subjective Fatigue During Prolonged Esports Across Player Expertise Levels

Cognitive fatigue, a transient cognitive decline stemming from extended mental and physical activity, is well established in conventional contexts. However, its manifestation and self-awareness during digital pursuits, as an integrated style of mental and physical activity, notably in electronic sports (esports), remain underexplored. Here we show that, using virtual football as a representative model for esports, prolonged esports cause cognitive fatigue with pupil constriction, independent of subjective fatigue across player expertise. Casual and hardcore esports players engaged in an intensive 3 hours gaming session, and sense of fatigue, executive function, pupil diameter as a potential signifier, and other physiological parameters were recorded. Subjective fatigue remained unchanged for up to 2 h, but increased after 3 hours, inversely linked to reported enjoyment, in both groups of players. Executive function, assessed by flanker interference, decreased after 2 h and 3 h in casual players. The accuracy of the flanker task decreased after 2 h and 3 h in hardcore players, despite an initial accuracy edge. Pupil diameter decreased after 2 h and 3 h and correlated with cognitive performance decline but diverged from subjective fatigue in both player types. Our findings clearly suggest a disparity between actual cognitive decline and subjective fatigue awareness in esports, transcending levels of player expertise. Pupil constriction is a potential neurobiological marker integrating divergent cognitive and subjective fatigue during digital engagement