Two-year clinical evaluation of one-step self-etch systems in non-carious cervical lesions.

OBJECTIVES: This randomized controlled clinical trial evaluated the 2-year clinical performance of S(3) Bond (S3) and G-Bond (GB) in 108 non-carious cervical lesions. METHODS: Twenty-three patients, 12 male and 11 female (mean age: 61.8 years, range: 30-79 years) regularly visiting the Nagasaki University Hospital of Medicine and Dentistry, participated in the study. Each patient received both materials randomly. All restorations (53 restorations for S3 and 55 restorations for GB) were placed by one dentist. The restorations were blindly evaluated by two examiners at baseline, 6 months, 1 and 2 years using modified USPHS criteria. The data were statistically analyzed using the Cochran Q test and Fisher\u27s exact test. RESULTS: One restoration of each material was lost during 2 years. The only minor clinical problem was the integrity of the enamel margin. Slight marginal staining occurred adjacent to 11 restorations of both S3 and GB. There was no significant difference in the clinical performance between S3 and GB for each variable. CONCLUSIONS: Under the protocol used in this study, S3 and GB have demonstrated an acceptable clinical performance up to 2 years

Nesting and post-nesting studies of loggerhead turtles (Caretta caretta) at Omaezaki, Japan

Organized by Graduate School of Informatics, Kyoto University ; JSPS Bangkok Liaison Office ; Japanese Society of Bio-logging Science ; Informatics Research Center for Development of Knowledge Society InfrastructureDecember 13-15, 2004, Imperial Tara Hotel, Bangkok, ThailandNesting biology, measurement of body size and mitochondrial (mt) DNA haplotypes of loggerhead turtle, Caretta caretta at Omaezaki Beach, Japan were investigated by collecting data and samples during night observations from 6 July to 6 August 2004. In addition, seven post-nesting females, which nested during this observation period, were tracked by satellite telemetry. A total of 33 females were identified in this observation period. Seven females nested twice, with a mean inter-nesting interval of 18.0 days. Even though our observations did not cover the entire nesting beach and period, the frequency of nesting was estimated at three, using a calculation based on the total number of nests at this beach in this nesting season. The range of straight carapace length (SCL) was from 65.8 to 91.6 cm, and the mean (±SD) size was 81.5±5.83 cm. The SCL of females at Omaezaki Beach is significantly lower than at other nesting sites in Japan based on calculation of 90% confidence intervals for mean SCLs. Two haplotypes were detected among 33 females using mitochondrial (mt) DNA analysis. Composition of these two haplotypes of nesting females at Omaezaki Beach was similar to nesting females at other nesting beaches in Japan. Post-nesting feeding grounds of seven loggerhead turtles released from Omaezaki consist of two areas, the northwestern North Pacific and the East China Sea. It is confirmed that nesting females at Omaezaki Beach were from the two groups using the different post-nesting feeding grounds and these two groups can be distinguished by their body size criterion of 85 cm. If different factors impact females in each feeding ground, monitoring the number of females and the composition of body size can be useful in assessing the impact to females

Diagnostic sensitivity of motor nerve conduction studies in ulnar neuropathy at the elbow.

Seventy-six patients with ulnar neuropathy at the elbow were divided into 3 classes (Grades I, II, and III) according to their clinical features and the maximal motor nerve conduction velocity (MCV), and the amplitude ratios at the across-elbow segment were retrospectively analyzed. To determine the criteria for abnormality, a control study was conducted on 150 healthy volunteers ranging in age from 20 to 89 years (6 age groups). The normal value for MCV could be set for two age groups: those under 60 and those over 60 years old. The 95% confidence limit was 54m/s for the former and 50m/s for the latter. There was no statistically significant difference in the amplitude ratio among the age groups. The confidence limit was set uniformly at 0.82 (above elbow/below elbow). An abnormality in either MCV or the amplitude ratio was found in 66.7% of Grade I (recent and mild symptoms), 89.7% of Grade II (persistent symptoms), and 100% of Grade III cases (marked intrinsic muscle atrophy). Evaluation using the combination of MCV and the amplitude ratio, considering the age-related normal value, appeared to be useful in establishing a differential diagnosis of ulnar neuropathy at the elbow.</p

The Ratio of Plasma Aldosterone Concentration to Potassium in Adrenocorticotropin Stimulation Test is a Possible New Index for Diagnosis of Aldosterone-producing Adenoma in Patients with Primary Aldosteronism

Article信州医学雑誌 63(3):145-156 (2015)journal articl

Disclosure of cancer and doctor's view of pharmacist : Investigation of doctor's view in University Hospital, The University of Tokushima School of Medicine

In the present study, we investigated the consensus in the truth telling of cancer and teaching about medication by pharmacists by using a questionnaire among 24 physicians in the Third Department of Internal Medicine, the University of Tokushima School of Medicine. At the same time, the data was compared to the previous investigation in 1995. The Physicians' opinion in the truth telling of cancer have changed in these seceral years, that is summarized as positive in truth telling. In 1995, 40% of the physicians were against to tell the truth with pharmacists, but in the present study, most physicians wanted to tell the truth with pharmacists. As for the teaching about medication by pharmacists, most physicians supported pharmacists to teach about medication, even to the patients who do not know the truth about their own cancer. These results suggest that it is necessary for the pharmacists to positively relate to the cacer patients through the truth telling and the teaching about medication

Hemangiopericytoma of the Greater Omentum

A 41-year-old Chinese woman was admitted to our hospital with epigastric pain. Computed tomography detected a heterogeneous enhancement tumor fed by the left gastroepiploic artery in the left lower quadrant and cholelithiasis. Excision of the tumor in the greater omentum and cholecystectomy were performed laparoscopically. Histological findings confirmed a diagnosis of hemangiopericytoma with low-grade malignancy. To our knowledge, hemangiopericytoma of the greater omentum is very rare, and only 12 cases were reported in English literature. We report a case of hemangiopericytoma arising in the greater omentum and review the literature

Risk Factors for Restenosis after Percutaneous Coronary Intervention with Sirolimus- and Paclitaxel-eluting Stents

To identify risk factors for restenosis after percutaneous coronary intervention with sirolimus (SES)- or paclitaxel (PES)-eluting stents. The clinical outcomes of 894 patients treated with either SES (n = 462) or PES (n = 432) between January 2005 and January 2010 were evaluated. Multivariate logistic regression analysis showed that long ( > 20mm)(odds ratio [OR], 1.87; 95% confidence interval [CI], 1.07-3.33; P = 0.03) or bent (angle > 45°) lesions (OR, 2.57; 95% CI, 1.47- 4.49; P < 0.01) were independent risk factors for restenosis with SES, and that hemodialysis (OR, 7.61; 95% CI, 2.78- 20.85; P < 0.01) and long (OR, 2.63; 95% CI, 1.18-5.84; P = 0.02) or bent lesions (OR, 3.47; 95% CI, 1.65-7.27;P < 0.01) were independent risk factors for target lesion revascularization (TLR) with SES. In contrast, no independent risk factors for restenosis and TLR were found for lesions treated with PES. The rate of TLR was significantly higher in patients on hemodialysis or in those with long lesions in the SES group (hemodialysis, 30.4% vs. 11.1%, P = 0.02; long lesions, 13.2% vs. 4.4%, P < 0.01; for SES vs. PES, respectively). Rates of restenosis and TLR were significantly higher in patients with bent lesions in the SES group (restenosis, 30.8% vs. 15.6%, P < 0.01; TLR, 20.0% vs. 5.8%, P < 0.01; for SES and PES, respectively). Most clinical studies have described better angiographic results for SES compared to PES. However, PES might result in better clinical outcomes than SES for patients on hemodialysis or for those with long or bent lesions

Comparison of Mid-term Angiographic and Clinical Outcomes Following Zotarolimus-eluting Stent and Paclitaxel-eluting Stent Implantation Based on Lesion Complexity

First-generation drug-eluting stents (DESs) have reduced angiographic and clinical restenosis rates compared to bare-metal stents (BMSs). Zotarolimus-eluting stents (ZESs) are second-generation drug-eluting stents: however, the clinical efficacy of ZES implantation is unclear because late loss associated with ZESs is reportedly higher than that observed for other DESs. The aim of this study was to evaluate the clinical efficacy of ZESs compared to paclitaxel-eluting stents (PESs). We retrospectively evaluated the angiographic and clinical outcomes of 431 lesions in 342 patients treated with PESs and 153 lesions in 121 patients treated with ZESs in our hospital between May 2007 and December 2010. Follow-up angiographic examinations were performed eight months post-treatment and clinical outcomes were assessed one year after the procedure. Quantitative coronary angiographic analyses showed that late loss was significantly higher for ZESs than PESs (0.82 ± 0.73 mm vs 0.47 ± 0.68 mm; P = 0.003). However, there was no significant difference in target lesion revascularization (TLR) between the two groups (ZES: 15 lesions, 9.8% vs PES: 25 lesions, 5.8%; P = 0.092). When comparing stents according to the American College of Cardiology/American Heart Association (ACC/AHA) lesion type, the TLR rate in the ZES group was significantly lower than in the PES group (0% vs 7.0%; P = 0.038) for Type A/B1 lesions, but the TLR rate for type B2/C lesions in the ZES group was significantly higher than in the PES group (15.8% vs 5.3%; P = 0.009). Multivariate logistic regression analysis showed that dialysis (OR: 35.54; 95% CI: 3.15-400.67; P = 0.039) and pre-minimal lumen diameter (OR: 0.036; 95% CI: 0.002-0.541; P = 0.016) were independent predictors of TLR in ZES-treated lesions. However, no factors predicted TLR in PES-treated lesions. Our study demonstrated excellent outcomes with ZESs for simple lesions, but it is necessary to carefully implant ZESs in complex lesions, such as ACC/AHA type B2/C lesions