Does Aqueous Fullerene Inhibit the Growth of Saccharomyces cerevisiae or Escherichia coli?

Studies reporting on potentially toxic interactions between aqueous fullerene nanoparticles (nC₆₀) and microorganisms have been contradictory. When known confounding factors were avoided, growth yields of Saccharomyces cerevisiae and Escherichia coli cultured in the presence and absence of independently prepared lots of underivatized nC₆₀ were found not to be significantly different.This is the publisher’s final pdf. The published article is copyrighted by the American Society for Microbiology and can be found at: http://aem.highwire.org/

Identification of gold nanoparticle-resistant mutants of Saccharomyces cerevisiae suggests a role for respiratory metabolism in mediating toxicity

Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion

Does Aqueous Fullerene Inhibit the Growth of Saccharomyces cerevisiae or Escherichia coli? ▿

Studies reporting on potentially toxic interactions between aqueous fullerene nanoparticles (nC60) and microorganisms have been contradictory. When known confounding factors were avoided, growth yields of Saccharomyces cerevisiae and Escherichia coli cultured in the presence and absence of independently prepared lots of underivatized nC60 were found not to be significantly different

SmithMarkFoodScienceTechnologyIdentificationGoldNanoparticle.pdf

Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion

SmithMarkFoodScienceTechnologyIdentificationGoldNanoparticle_SupplementalFile2.pdf

Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion

BakalinskyAlanFoodScienceTechnologyIdentificationGoldNanoparticle.pdf

Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion

SmithMarkFoodScienceTechnologyIdentificationGoldNanoparticle_SupplementalFile1.pdf

Positively-charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion