4,895 research outputs found
Possible explanations for different surface quality in laser cutting with 1 micron and 10 microns beams
In laser cutting of thick steel sheets, quality difference is observed between cut surfaces obtained with 1 micron and 10 micron laser beams. This paper investigates physical mechanisms for this interesting and important problem of the wavelength dependence. First, striation generation process is described, based on a 3D structure of melt flow on a kerf front, which was revealed for the first time by our recent experimental observations. Two fundamental processes are suggested to explain the difference in the cut surface quality: destabilization of the melt flow in the central part of the kerf front and downward displacement of discrete melt accumulations along the side parts of the front. Then each of the processes is analyzed using a simplified analytical model. The results show that in both processes, different angular dependence of the absorptivity of the laser beam can result in the quality difference. Finally we propose use of radial polarization to improve the quality with the 1 micron wavelength
A novel mode of capping protein-regulation by Twinfilin
Cellular actin assembly is controlled at the barbed ends of actin filaments, where capping protein (CP) limits polymerization. Twinfilin is a conserved in vivo binding partner of CP, yet the significance of this interaction has remained a mystery. Here, we discover that the C-terminal tail of Twinfilin harbors a CP-interacting (CPI) motif, identifying it as a novel CPI-motif protein. Twinfilin and the CPI-motif protein CARMIL have overlapping binding sites on CP. Further, Twinfilin binds competitively with CARMIL to CP, protecting CP from barbed-end displacement by CARMIL. Twinfilin also accelerates dissociation of the CP inhibitor V-1, restoring CP to an active capping state. Knockdowns of Twinfilin and CP each cause similar defects in cell morphology, and elevated Twinfilin expression rescues defects caused by CARMIL hyperactivity. Together, these observations define Twinfilin as the first \u27pro-capping\u27 ligand of CP and lead us to propose important revisions to our understanding of the CP regulatory cycle
The nuclear scissors mode within two approaches (Wigner function moments versus RPA)
Two complementary methods to describe the collective motion, RPA and Wigner
function moments method, are compared on an example of a simple model -
harmonic oscillator with quadrupole-quadrupole residual interaction. It is
shown that they give identical formulae for eigenfrequencies and transition
probabilities of all collective excitations of the model including the scissors
mode, which here is the subject of our special attention. The exact relation
between the variables of the two methods and the respective dynamical equations
is established. The normalization factor of the "synthetic" scissors state and
its overlap with physical states are calculated analytically. The orthogonality
of the spurious state to all physical states is proved rigorously.Comment: 39 page
Characterization of the mrgRS locus of the opportunistic pathogen Burkholderia pseudomallei: temperature regulates the expression of a two-component signal transduction system
BACKGROUND: Burkholderia pseudomallei is a saprophyte in tropical environments and an opportunistic human pathogen. This versatility requires a sensing mechanism that allows the bacterium to respond rapidly to altered environmental conditions. We characterized a two-component signal transduction locus from B. pseudomallei 204, mrgR and mrgS, encoding products with extensive homology with response regulators and histidine protein kinases of Escherichia coli, Bordetella pertussis, and Vibrio cholerae. RESULTS: The locus was present and expressed in a variety of B. pseudomallei human and environmental isolates but was absent from other Burkholderia species, B. cepacia, B. cocovenenans, B. plantarii, B. thailandensis, B. vandii, and B. vietnamiensis. A 2128 bp sequence, including the full response regulator mrgR, but not the sensor kinase mrgS, was present in the B. mallei genome. Restriction fragment length polymorphism downstream from mrgRS showed two distinct groups were present among B. pseudomallei isolates. Our analysis of the open reading frames in this region of the genome revealed that transposase and bacteriophage activity may help explain this variation. MrgR and MrgS proteins were expressed in B. pseudomallei 204 cultured at different pH, salinity and temperatures and the expression was substantially reduced at 25°C compared with 37°C or 42°C but was mostly unaffected by pH or salinity, although at 25°C and 0.15% NaCl a small increase in MrgR expression was observed at pH 5. MrgR was recognized by antibodies in convalescent sera pooled from melioidosis patients. CONCLUSION: The results suggest that mrgRS regulates an adaptive response to temperature that may be essential for pathogenesis, particularly during the initial phases of infection. B. pseudomallei and B. mallei are very closely related species that differ in their capacity to adapt to changing environmental conditions. Modifications in this region of the genome may assist our understanding of the reasons for this difference
M dwarf stars in the light of (future) exoplanet searches
We present a brief overview of a splinter session on M dwarf stars as planet
hosts that was organized as part of the Cool Stars 17 conference. The session
was devoted to reviewing our current knowledge of M dwarf stars and exoplanets
in order to prepare for current and future exoplanet searches focusing in low
mass stars. We review the observational and theoretical challenges to
characterize M dwarf stars and the importance of accurate fundamental
parameters for the proper characterization of their exoplanets and our
understanding on planet formation.Comment: 4 pages, 1 figure. Summary of the splinter session "M dwarf stars in
the light of (future) exoplanet searches" held at the 17th Cambridge Workshop
on Cool Stars, Stellar Systems, and the Sun, June 28th 2012, Barcelona,
Spain. Submitted for publication in Astronomische Nachrichten - Astronomical
Notes (AN) 334, Issue 1-2, Eds Klaus Strassmeier and Mercedes L\'opez-Morale
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Analysis of phosphorus use efficiency traits in Coffea genotypes reveals Coffea arabica and Coffea canephora have contrasting phosphorus uptake and utilization efficiencies
Background and Aims: Phosphate (Pi) is one of the most limiting nutrients for agricultural production in Brazilian soils due to low soil Pi concentrations and rapid fixation of fertilizer Pi by adsorption to oxidic minerals and/or precipitation by iron and aluminum ions. The objectives of this study were to quantify phosphorus (P) uptake and use efficiency in cultivars of the species Coffea arabica L. and Coffea canephora L., and group them in terms of efficiency and response to Pi availability.
Methods: Plants of 21 cultivars of C. arabica and four cultivars of C. canephora were grown under contrasting soil Pi availabilities. Biomass accumulation, tissue P concentration and accumulation and efficiency indices for P use were measured.
Key Results: Coffee plant growth was significantly reduced under low Pi availability, and P concentration was higher in cultivars of C. canephora. The young leaves accumulated more P than any other tissue. The cultivars of C. canephora had a higher root/shoot ratio and were significantly more efficient in P uptake, while the cultivars of C. arabica were more efficient in P utilization. Agronomic P use efficiency varied among coffee cultivars and E16 Shoa, E22 Sidamo, Iêmen and Acaiá cultivars were classified as the most efficient and responsive to Pi supply. A positive correlation between P uptake efficiency and root to shoot ratio was observed across all cultivars at low Pi supply. These data identify Coffea genotypes better adapted to low soil Pi availabilities, and the traits that contribute to improved P uptake and use efficiency. These data could be used to select current genotypes with improved P uptake or utilization efficiencies for use on soils with low Pi availability and also provide potential breeding material and targets for breeding new cultivars better adapted to the low Pi status of Brazilian soils. This could ultimately reduce the use of Pi fertilizers in tropical soils, and contribute to more sustainable coffee production
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Universal interpretations of vocal music
Despite the variability of music across cultures, some types of human songs share acoustic characteristics. For example, dance songs tend to be loud and rhythmic, and lullabies tend to be quiet and melodious. Human perceptual sensitivity to the behavioral contexts of songs, based on these musical features, suggests that basic properties of music are mutually intelligible, independent of linguistic or cultural content. Whether these effects reflect universal interpretations of vocal music, however, is unclear because prior studies focus almost exclusively on English-speaking participants, a group that is not representative of humans. Here, we report shared intuitions concerning the behavioral contexts of unfamiliar songs produced in unfamiliar languages, in participants living in Internet-connected industrialized societies (n = 5,516 native speakers of 28 languages) or smaller-scale societies with limited access to global media (n = 116 native speakers of three non-English languages). Participants listened to songs randomly selected from a representative sample of human vocal music, originally used in four behavioral contexts, and rated the degree to which they believed the song was used for each context. Listeners in both industrialized and smaller-scale societies inferred the contexts of dance songs, lullabies, and healing songs, but not love songs. Within and across cohorts, inferences were mutually consistent. Further, increased linguistic or geographical proximity between listeners and singers only minimally increased the accuracy of the inferences. These results demonstrate that the behavioral contexts of three common forms of music are mutually intelligible cross-culturally and imply that musical diversity, shaped by cultural evolution, is nonetheless grounded in some universal perceptual phenomena
Perpendicular momentum injection by lower hybrid wave in a tokamak
The injection of lower hybrid waves for current drive into a tokamak affects
the profile of intrinsic rotation. In this article, the momentum deposition by
the lower hybrid wave on the electrons is studied. Due to the increase in the
poloidal momentum of the wave as it propagates into the tokamak, the parallel
momentum of the wave increases considerably. The change of the perpendicular
momentum of the wave is such that the toroidal angular momentum of the wave is
conserved. If the perpendicular momentum transfer via electron Landau damping
is ignored, the transfer of the toroidal angular momentum to the plasma will be
larger than the injected toroidal angular momentum. A proper quasilinear
treatment proves that both perpendicular and parallel momentum are transferred
to the electrons. The toroidal angular momentum of the electrons is then
transferred to the ions via different mechanisms for the parallel and
perpendicular momentum. The perpendicular momentum is transferred to ions
through an outward radial electron pinch, while the parallel momentum is
transferred through collisions.Comment: 22 pages, 4 figure
INPOP08, a 4-D planetary ephemeris: From asteroid and time-scale computations to ESA Mars Express and Venus Express contributions
The latest version of the planetary ephemerides developed at the Paris
Observatory and at the Besancon Observatory is presented here. INPOP08 is a
4-dimension ephemeris since it provides to users positions and velocities of
planets and the relation between TT and TDB. Investigations leading to improve
the modeling of asteroids are described as well as the new sets of observations
used for the fit of INPOP08. New observations provided by the European Space
Agency (ESA) deduced from the tracking of the Mars Express (MEX) and Venus
Express (VEX) missions are presented as well as the normal point deduced from
the Cassini mission. We show the huge impact brought by these observations in
the fit of INPOP08, especially in terms of Venus, Saturn and Earth-Moon
barycenter orbits.Comment: 14 pages. submitted to A&A. accepted in A&
Superconducting Transition Edge Sensor Using Dilute AlMn Alloys
We have fabricated a bolometer using a transition-edge sensor (TES) made of Al doped with Mn to suppress the superconducting critical temperature (Tc) of Al from ∼1Kto∼100mK. The resulting detector exhibits low-frequency noise consistent with theory, with a noise-equivalent power of 7.5×10−18W/√Hz. The addition of Mn impurities did not significantly increase the heat capacity of the TES. In addition, the detector is surprisingly insensitive to applied magnetic fields. The use of AlMn alloy films in arrays of TES detectors has advantages in simplicity of fabrication when compared to traditional bilayer fabrication techniques
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