87 research outputs found

    Isoforms of transferrin in psoriasis patients abusing alcohol

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    The different isoforms of transferrin have been quantified by isoelectric focusing in the sera of psoriasis patients with and without a history of abusing alcohol. In both male and female psoriasis subjects abusing alcohol, there were significant increases in the 2-sialylated forms by comparison to the control subjects. Psoriasis patients who had no evidence of alcohol abuse had similar profile for the isoforms of transferrin to that of the controls. Other groups of patients with alcohol-induced tissue damage, i.e. liver, brain or muscle, used as positive controls, similarly showed significant increases in the 2-sialylated forms, by comparison to controls. These results substantiate the current use of carbohydrate-deficient transferrin as a sensitive marker of alcohol abuse, particularly in subjects not drinking in excess of 60 g of ethanol/day but showing alcohol-related psoriasis

    The validity and reliability of the exposure index as a metric for estimating the radiation dose to the patient

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    Introduction With the introduction of digital radiography, the feedback between image quality and over-exposure has been partly lost which in some cases has led to a steady increase in dose. Over the years the introduction of exposure index (EI) has been used to resolve this phenomenon referred to as ‘dose creep’. Even though EI is often vendor specific it is always a related of the radiation exposure to the detector. Due to the nature of this relationship EI can also be used as a patient dose indicator, however this is not widely investigated in literature. Methods A total of 420 dose-area-product (DAP) and EI measurements were taken whilst varying kVp, mAs and body habitus on two different anthropomorphic phantoms (pelvis and chest). Using linear regression, the correlation between EI and DAP were examined. Additionally, two separate region of interest (ROI) placements/per phantom where examined in order to research any effect on EI. Results When dividing the data into subsets, a strong correlation between EI and DAP was shown with all R-squared values > 0.987. Comparison between the ROI placements showed a significant difference between EIs for both placements. Conclusion This research shows a clear relationship between EI and radiation dose which is dependent on a wide variety of factors such as ROI placement, body habitus. In addition, pathology and manufacturer specific EI’s are likely to be of influence as well. Implications for practice The combination of DAP and EI might be used as a patient dose indicator. However, the influencing factors as mentioned in the conclusion should be considered and examined before implementation

    Development of an approximate method for quantum optical models and their pseudo-Hermicity

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    An approximate method is suggested to obtain analytical expressions for the eigenvalues and eigenfunctions of the some quantum optical models. The method is based on the Lie-type transformation of the Hamiltonians. In a particular case it is demonstrated that EĂ—Ï”E\times \epsilon Jahn-Teller Hamiltonian can easily be solved within the framework of the suggested approximation. The method presented here is conceptually simple and can easily be extended to the other quantum optical models. We also show that for a purely imaginary coupling the EĂ—Ï”E\times \epsilon Hamiltonian becomes non-Hermitian but Pσ0P\sigma _{0}-symmetric. Possible generalization of this approach is outlined.Comment: Paper prepared fo the "3rd International Workshop on Pseudo-Hermitian Hamiltonians in Quantum Physics" June 2005 Istanbul. To be published in Czechoslovak Journal of Physic

    A sensorimotor control framework for understanding emotional communication and regulation

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    JHGW and CFH are supported by the Northwood Trust. TEVR was supported by a National Health and Medical Research Council (NHMRC) Early Career Fellowship (1088785). RP and MW were supported by the the Australian Research Council (ARC) Centre of Excellence for Cognition and its Disorders (CE110001021)Peer reviewedPublisher PD

    Parallel CLUSTAL W for PC Clusters

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    This paper presents a parallel version of CLUSTAL W, called pCLUSTAL. In contrast to the commercial SGI parallel Clustal, which requires an expensive shared memory SGI multiprocessor, pCLUSTAL can be run on a range of distributed and shared memory parallel machines, from high-end parallel multiprocessors (e.g. Sunfire 6800, IBM SP2, etc.) to PC clusters, to simple networks of workstations. We have implemented pCLUSTAL using C and the MPI communication library, andtesteditonaPCcluster.Ourexperimentalevaluationshowsthat our pCLUSTAL code achieves similar or better speedup on a distributed memory PC clusters than the commercial SGI parallel Clustal on a shared memory SGI multiprocessor
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