7 research outputs found
Tenofovir (TDF) has stronger antiviral effect than adefovir (ADV) against lamivudine (LAM)-resistant hepatitis B virus (HBV)
- Author
- Publication venue
- Springer-Verlag
- Publication date
- Field of study
Neural regeneration along longitudinal polyglactin sutures across short and extended defects in the rat sciatic nerve
- Author
- Publication venue
- 'Journal of Neurosurgery Publishing Group (JNSPG)'
- Publication date
- Field of study
DISC: a highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semi-supervised deep learning
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Proteomic Analysis of the Anti-Cancer Effect of 20 S
- Author
- Alfonso P Nunez A, Madoz-Gurpide J
- Ebert MN Beyer-Sehlmeyer G, Liegib
- Geun Tae KIM
- Haider SK Anumanthan G, Maddula R,
- Hie-Joon KIM
- Jeong Hill PARK
- Jin-Su SONG
- Keum YS Seong SH, Chun KS, Park KK
- Lavezzi AM Ottaviani G, De Ruberto
- MOCHIZUKI M
- O&rsquo
- Raynal P and Pollard HB
- Royle SJ
- Seo Young LEE
- Si Hun ROH
- Soon-Sun HONG
- Sung Won KWON
- Zhang BL
- Zhang BL Zhang YQ, Dagher MC, and
- Publication venue
- 'Japan Society for Bioscience, Biotechnology, and Agrochemistry'
- Publication date
- Field of study
Thrombotic thrombocytopenic purpura
- Author
- A Bernardo
- A Cuker
- A Froissart
- A Nosari
- A Rottenstreich
- A Schiviz
- A Tripodi
- A Vazquez-Mellado
- A Veyradier
- A Veyradier
- A Ziman
- AE Eskazan
- AS Kennedy
- AS von Krogh
- AS von Krogh
- B Plaimauer
- B Plaimauer
- BC Biedermann
- BJ Hunt
- BM Luken
- BM Luken
- C Gasser
- C Gervasoni
- C Hughes
- C Klaus
- C Tersteeg
- C Tersteeg
- C Tersteeg
- CA Karpac
- CA Siedlecki
- CC Deford
- CJ Patriquin
- CL Balduini
- CL Bennett
- CL Bennett
- CL Verweij
- DJ Groeneveld
- DR Terrell
- E De Cock
- E Mariotte
- E Moschcowitz
- E Tsai
- EE Page
- EE Page
- EL Amorosi
- EM Majerus
- F Beloncle
- F Langer
- F Peyvandi
- F Peyvandi
- F Peyvandi
- F Scheiflinger
- FC Verbij
- G Antoine
- G Cabanillas
- GA Rock
- GA Veltman
- GG Levy
- GW Li
- H Yagi
- HB Feys
- HB Feys
- HB Feys
- HE Gerritsen
- HM Tsai
- HM Tsai
- HM Tsai
- HM Tsai
- HT Ling
- I Mackie
- I Schulman
- J Chapin
- J Chen
- J de la Rubia
- J Muia
- J Muia
- J Shortt
- JA Kremer Hovinga
- JA Kremer Hovinga
- JA Kremer Hovinga
- JA Kremer Hovinga
- JA Kremer Hovinga
- JA Reese
- JD Studt
- JD Upshaw
- JE Sadler
- JJ Hulstein
- JL Moake
- JL Moake
- JN George
- JN George
- JS Raval
- JT Crawley
- JT Crawley
- K Assink
- K Fujikawa
- K Gunther
- K Kokame
- K Kokame
- K Kokame
- K Kokame
- K Soejima
- K South
- L Deforche
- L Liu
- L Nguyen
- L Nolasco
- LA Lotta
- LA Lotta
- M Akiyama
- M Benjamin
- M Furlan
- M Furlan
- M Furlan
- M Furlan
- M Furlan
- M Galbusera
- M Hie
- M Jin
- M Jin
- M Manea
- M Manea
- M Mansouri Taleghani
- M Mansouri Taleghani
- M Matsumoto
- M Matsumoto
- M Matsumoto
- M Moatti-Cohen
- M Noris
- M Noris
- M Reti
- M Rieger
- M Rieger
- M Roriz
- M Schaller
- M Scully
- M Scully
- M Scully
- M Scully
- M Scully
- M Scully
- M Soucemarianadin
- M Uemura
- MA Mazepa
- MC Kappers-Klunne
- ML John
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- N Sorvillo
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- P Coppo
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- QF Lewis
- R de Groot
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- R Grillberger
- R Schneppenheim
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- RL Ridolfi
- RS Camilleri
- S Dundas
- S Feng
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- S Ferrari
- S Ferrari
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- S Jasti
- S Kinoshita
- S Ko
- S Malak
- S Martino
- S Som
- S Zanardelli
- SC Meyer
- SC Meyer
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- SC Meyer
- SD Berkowitz
- SF De Meyer
- SF De Meyer
- SK Vesely
- SL Allford
- SR Cataland
- SR Cataland
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- SY Jin
- T Matsuyama
- T Miyata
- TA Fuchs
- TJ Raife
- TJ Török
- VC Casina
- VG Pillai
- VX Du
- W Pos
- W Pos
- W Pos
- W Zhou
- WR Bell
- X Fan
- X Zheng
- XL Zheng
- XL Zheng
- Y Benhamou
- Y Benhamou
- Y Fujimura
- Y Fujimura
- Y Jiang
- Y Kume
- Z Tao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 06/04/2017
- Field of study
Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is characterized by the concomitant occurrence of often severe thrombocytopenia, microangiopathic haemolytic anaemia and a variable degree of ischaemic organ damage, particularly affecting the brain, heart and kidneys. Acute TTP was almost universally fatal until the introduction of plasma therapy, which improved survival from <10% to 80-90%. However, patients who survive an acute episode are at high risk of relapse and of long-term morbidity. A timely diagnosis is vital but challenging, as TTP shares symptoms and clinical presentation with numerous conditions, including, for example, haemolytic uraemic syndrome and other thrombotic microangiopathies. The underlying pathophysiology is a severe deficiency of the activity of a disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS13), the protease that cleaves von Willebrand factor (vWF) multimeric strings. Ultra-large vWF strings remain uncleaved after endothelial cell secretion and anchorage, bind to platelets and form microthrombi, leading to the clinical manifestations of TTP. Congenital TTP (Upshaw-Schulman syndrome) is the result of homozygous or compound heterozygous mutations in ADAMTS13, whereas acquired TTP is an autoimmune disorder caused by circulating anti-ADAMTS13 autoantibodies, which inhibit the enzyme or increase its clearance. Consequently, immunosuppressive drugs, such as corticosteroids and often rituximab, supplement plasma exchange therapy in patients with acquired TTP
Regulation of immune responses by the airway epithelial cell landscape
- Author
- A Broggi
- A Iwasaki
- A Pardo-Saganta
- A Tata
- A Toubal
- A Wallrapp
- AC Habermann
- AE Oja
- AG Solis
- AJ Byrne
- AT Shenoy
- B Hie
- B Treutlein
- BV Kumar
- BW Richmond
- C Godinho-Silva
- C Morse
- C Schneider
- C Schneider
- C Trapnell
- CE O’Leary
- CE Prendergast
- CGK Ziegler
- CS Klose
- CSN Klose
- D Blanco-Melo
- D Hashimoto
- D Masopust
- D Trankner
- DJ Slebos
- DL Turner
- DL Turner
- DR Revinski
- DT Montoro
- E Madissoon
- E Mereu
- F Puttur
- F Puttur
- FA Vieira Braga
- FE Johansen
- G Krasteva
- G La Manno
- G Natoli
- GB Huffnagle
- GE Duclos
- H Chen
- H Nagashima
- H Song
- H Wang
- H Wu
- HB Schiller
- HG Moon
- HM Coleridge
- I Angelidis
- IJ Juncadella
- IK Quigley
- J Barrios
- J Barrios
- J Gibbs
- J Major
- J Ordovas-Montanes
- J Ordovas-Montanes
- J Ordovas-Montanes
- J von Moltke
- JA Rhodin
- JC Schupp
- JE Boers
- JE Boers
- JE Gibbs
- JE Gibbs
- JH Widdicombe
- JK Watson
- JMG Higgins
- JR Huh
- JR Rock
- JR Rock
- JS Elborn
- JV Fahy
- K Branchfield
- K Brune
- K Man
- K Westphalen
- KC Goldfarbmuren
- KH Benam
- L Haghverdi
- L Tao
- LE Kistemaker
- LE Zaragosi
- LG Bankova
- LK Beura
- LW Plasschaert
- M Deprez
- M Efremova
- M Guilliams
- M Liao
- M Nakajima
- M Pariollaud
- M Tizzano
- MA Kohanski
- MC Basil
- MD Luecken
- ME Snyder
- MI Hollenhorst
- MS Nadjsombati
- MSB Raredon
- N Fujino
- P Baral
- P Bastard
- P Ramachandran
- P Sui
- PD Vermeer
- PM Henson
- PS Hiemstra
- Q Zhang
- R Channappanavar
- R Lehmann
- R Shaykhiev
- R Vento-Tormo
- RG Breeze
- RI Linnoila
- RJ Pack
- RL Chua
- RN Germain
- RP Schleimer
- RR Mercer
- S Abolins
- S Ruiz GarcĂa
- S Takamura
- S Talbot
- S Ualiyeva
- SC van den Brink
- SG Rodriques
- SJ Ellis
- SL Hayward
- SL Prescott
- SR White
- TS Adams
- TS Hinks
- TSC Hinks
- V Bergen
- W Saelens
- W Sungnak
- X Liu
- X Yan
- Y Xu
- YA Alpizar
- YR Yu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Enzyme Handbook
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- [11] Taylor A., Volz, K.W., Lipscomb, W.N., Takemoto, L. J.
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- [hie J.N., Dure, L.S.
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- A Barth
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- AV Hoffbrand
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- Chan. S.A.T., Jones, T.H.D., Sweeney, J.P., Toursarkissian, K.
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- Xin-Ii Lin Wong, R.N.S., Tang, J.
- Y Agrawal
- Y Agrawal
- Y Atsumi
- Y Bai
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- “ (Turk V., Neville, M.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1991
- Field of study