Trends in the Levels of Serum Lipids and Lipoproteins and the Prevalence of Dyslipidemia in Adults with Newly Diagnosed Type 2 Diabetes in the Southwest Chinese Han Population during 2003–2012

Objective. To determine the trends of serum lipid levels and dyslipidemia in adults newly diagnosed with type 2 diabetes mellitus during 2003–2012 in Southwest China. Methods. Serum lipid measurements of 994 adults were obtained from 5 independent, cross-sectional studies (2003-2004, 2005-2006, 2007-2008, 2009-2010, and 2011-2012). The main outcome measures were mean serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglyceride levels; body mass index; hemoglobin A1C level; and the percentages of patients with dyslipidemia, hypertension, coronary heart disease, and cerebrovascular disease. Results. The mean total cholesterol and low-density lipoprotein cholesterol levels increased from 4.92 ± 1.15 to 5.30 ± 1.17 mmol/L (P = 0.039) and 2.72 ± 0.83 to 3.11 ± 1.09 mmol/L (P = 0.004), respectively, and the mean HDL cholesterol level declined from 1.22 ± 0.30 to 1.06 ± 0.24 mmol/L (P < 0.001). The percentages of patients with dyslipidemia increased gradually. The incidence of coronary heart and cerebrovascular diseases increased from 8.2% to 19.1% and 6.6% to 15.3%, respectively (P < 0.05). Conclusion. Unfavorable upward trends were observed in serum lipid levels and the prevalence of dyslipidemia, coronary heart disease, and cerebrovascular disease in adults newly diagnosed with type 2 diabetes mellitus in Southwest China during 2003–2012

Applications of Matching and Sorting Theory to Topics in Operations Management

Matching and sorting theory are widely applied to operations management. Our analysis focuses on the matching in supply chains and sorting between projects and heterogeneous firms. In chapter 1, we investigate the decentralized allocation in pharmaceutical research and development (R&D) projects. We construct a theoretical framework of R&D competition between heterogeneous firms for differentiated drugs. The decentralized allocation features a mismatch between firms and R&D projects. Efficient outcome prescribes that each firm works on a separate R&D project with the more valuable R&D project being allocated to the established firm. The impact of transparency on efficiency is contingent on the disclosure rules and may not improve the welfare. We also demonstrate the trade-off between the firm revenue and positive externality of the development of new drugs. Our research extends the R&D competition to a two-sided heterogeneous case and enriches the transparency analysis. In chapter two, we analyze a decentralized assortative matching model for bilateral supply chains. The risk-averse suppliers and retailers match mutually to form as supply chains, in which each supply chain optimally determines production plans and revenue sharing contracts. We show that in equilibrium, the less risk averse firm is not always matched with higher risk averse firm to share risk and revenue. We find that both positive assortative matching (PAM) and negative assortative matching (NAM) can occur in equilibrium. Equilibrium sorting pattern depends on the trade-off between the expected revenue and demand uncertainty. The main results extend the supply chain matching research by endogenizing both production choice and risk sharing contract

Analysis of the influence of different soil properties on the strength characteristics of cement soil

When deep cement mixing method (DCM) uses cement as solidified material to treat marine soft foundation, the strength of soil is different due to the diversity of water content, void ratio and particle fineness. Based on the Pearl River Estuary DCM project, this paper uses a variety of PO.42.5 cement and marine soft soil in the Pearl River estuary area to carry out indoor mix proportion tests. There are four kinds of soil: flowing mud, silt, muddy soil and silt. The test results show that the strength of cement soil in different soil layers is diversity. The effect of cement solidification treatment on silt and muddy soil is good, followed by silt, and flowing mud is slightly poor. The selected PO.42.5 cement can meet the strength requirements of DCM

Research on image recognition method of rock and soil porous media based on dithering algorithm

Rock-soil mass is a kind of material with complex internal structure, and its macro-mechanical response and failure process are influenced by internal microscopic composition and structure. Based on the research results of digital image technology in quantitative aspects of internal structure of rock and soil, a method for segmentation of rock and soil pore images based on dithering algorithm and statistical method for multiple parameters of pores is proposed in this paper. The result of verification shows that the pore recognition method proposed in this paper is reliable, can obtain the pore distribution and related parameters quickly and effectively, which has certain academic value and research significance

Application of comprehensive advanced geological prediction technology in Da-puling tunnel

For the Da-puling tunnel of Puqing Expressway in Guangxi, the advanced geological prediction is carried out by combining TSP long-distance forecast method with short distance geological radar method. This paper describes the principle of seismic wave propagation in elastic medium, as well as the key points of data processing and analysis, some requirements that should be paid attention to the field test and scientific way of image interpretation put forward to improve the accuracy of prediction; When TSP is deployed, it should be sharp angle with potential joint surface. P-wave reacts surrounding rock properties, the shear wave is closely related to the transverse skeleton of medium. In data interpretation, it is necessary to focus on the analysis of the characteristics of P-wave and S-wave, weakening Poisson’s ratio and Young’s modulus. TSP and GPR can achieve the mutual complement and improve the detection accuracy

The Improvement and application of elevation measurement method with total station

In this paper, by analyzing the limitations of the traditional trigonometric elevation method, and on the basis of establishing a mathematical model of trigonometric elevation, a convenient and fast trigonometric elevation method without instrument height and prism height is improved, and the operation steps of the method are introduced in detail. The accuracy analysis was evaluated and the method was applied to actual engineering. The results show that under the premise of ensuring the measurement accuracy, this method not only reduces the range of measurement error sources, but also improves the measurement efficiency