Estudio mediante el método de elementos finitos de la mecánica y la motilidad celular en diferentes ambientes confinados

En este trabajo lo que se pretende es estudiar la forma en que las células cancerígenas migran en un ambiente confinado en tres dimensiones. Más específicamente los procesos de extravasación e intravasación en los que este tipo de células se deforman mucho más que otras para abandonar el tumor de origen y metastatizar en un tumor secundario. Este estudio se va a centrar en observar cómo se mueve la célula cancerígena al pasar por ttres canales diferentes con distintas geometrías. En estos canales se simulará la migración de este tipo de células estudiando la influencia de los componentes del citoesqueleto de la célula, así como el grado de adhesión en el canal. <br /

The volume of ERCP per endoscopist is associated with a higher technical success and a lower post-ERCP pancreatitis rate. A prospective analysis

Introduction: conflicting results have been reported regarding the influence of the annual volume of endoscopic retrograde cholangiopancreatography (ERCP) on outcome. Objective: to evaluate the influence of case volume on ERCP outcomes. Patients and methods: an analysis of a prospective database was performed, comparing the outcomes of ERCP in three consecutive periods defined by the number of endoscopists performing ERCP: five endoscopists in period I (P1), four in period II (P2) and three in period III (P3). Only patients with biliary ERCP in accessible and naïve papilla were included. Primary variables were cannulation rates and adverse effects (AE). The American Society of Gastrointestinal Endoscopy (ASGE) complexity grades III and IV were considered as highly complex procedures. Results: a total of 2,561 patients were included: 727 (P1), 972 (P2) and 862 (P3). There were no differences in age and sex between groups (p > 0.05). The cannulation rate was significantly higher in P2 and P3: 92.4 % vs 93.3 % vs 93 % (p = 0.037). The AE rate was 13.8 %, 12.6 % and 10.3 % (p > 0.05), respectively. The rate of post-ERCP pancreatitis was significantly lower in P3: 8.5 %, 7.3 % and 5 % (p = 0.01). The rate of complex procedures was 12 %, 14.8 % and 27 % (p < 0.0001), respectively. Two endoscopists participated in all periods and only one had significantly improved outcomes. Cannulation and post-ERCP pancreatitis rates remained significantly better in P3 after adjusting for sex, complexity and endoscopist. Conclusion: a higher annual volume of ERCP per endoscopist was associated with a higher rate of cannulation and a lower rate of post-ERCP pancreatitis, despite the greater complexity of the procedures. These beneficial effects seem to differ between endoscopists

Molecular characterization of the diet of the planktonic community in Málaga Bay (NW Alboran Sea)

The seasonal changes in structure and functioning of the pelagic trophic web in Málaga Bay (NW Alboran Sea) are related to the annual hydrological cycle. However, time series analyses have shown that the relationship between interannual hydrological variability and the plankton community composition is weak. This might be due to different human-induced pressures (nutrient pollution, coastal fisheries) acting on different compartments of the trophic web. The net effect of all these factors would depend on how the ecosystem channels changes in the composition and abundance of each trophic level. Interactions of phytoplankton-ciliates-zooplankton might have a central role in the regulation of the trophic web in Málaga Bay, although the trophic relations of the dominant groups remain still undefined. In order to identify the dominant trophic relationships we aimed to characterise the diet of key ichthyo- and mesozooplankton species in the field. Given that gut content preys (phyto- and microplankton) are fragile and not easy to identify visually, we developed species-specific molecular markers to detect their presence/absence within the predators gut

Proyecto Puentes: conectando la universidad con la salud mental comunitaria

Se presenta la memoria del Proyecto Puentes, cuya finalidad es explorar e implementar vías de participación entre la comunidad universitaria y las personas con problemas de salud mental. Es decir, tender puentes entre lo académico y la realidad de esas personas, con el propósito de conseguir una fuente de aprendizaje significativo para el estudiantado de la UCM, pero también herramientas útiles en los procesos de recuperación e integración de las personas con problemáticas de salud mental.Depto. de Personalidad, Evaluación y Psicología ClínicaFac. de PsicologíaFALSEsubmitte

Teaching innovation applied in Health Sciences based on the detection of student learning strategies

El Objetivo principal se ha centrado en la innovación docente aplicada a un mejor aprendizaje por parte del alumnado en módulos de Ciencias de la Salud relativos a discapacidadDepto. de Radiología, Rehabilitación y FisioterapiaFac. de MedicinaFALSEsubmitte

Molecular identification of the zooplanktonic diet of Sardina pilchardus larvae in the SW Mediterranean Sea

Zooplankton are the main prey for small pelagic fishes. The most common small pelagic fish species in the Alboran Sea (SW Mediterranean Sea) is the European sardine (Sardina pilchardus). Despite its commercial importance in the region, little is known about its larval trophodynamics and the role that zooplankton play in their recruitment success. Microscopic characterization of the larval gut contents is challenging as they prey mostly on partly digested microplanktonic organisms. Several molecular tools have been developed that may overcome this caveat. The gut content of sardine larvae (6 - 21 mm standard length) collected over a diel cycle in the Northern Alboran Sea was analyzed by mitochondrial COI metabarcoding, and compared with the field zooplankton community composition. Diel variability was observed in zooplankton relative abundances, both in the larval gut contents and in the field. Sardine larvae preys included several copepod nauplii, but also DNA of cladocera, euphausiid, gastropod and hydrozoa was detected, suggesting an opportunistic foraging behavior, instead of a selective diet.Consejería de Economía, Innovación y Ciencia de la Junta de Andalucía; Unión Europea, Fondo Europeo de Desarrollo Regional (P20_00743