13 research outputs found
Psychological aspects and predictors of satisfaction in facial cosmetic surgery
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199056.pdf (publisher's version ) (Open Access)Radboud University, 16 januari 2019Promotores : Marres, H.A.M., Prins, J.B.
Co-promotores : Ingels, K.J.A.O., Heerbeek, N. va
Does self-consciousness of appearance influence postoperative satisfaction in rhinoplasty?
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183919.pdf (publisher's version ) (Closed access
Patient-reported outcome measurement in upper blepharoplasty: How to measure what the patient sees
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195287.pdf (publisher's version ) (Closed access
L'influence de la langue sur la capacité d'imagerie du mouvement
Impact de deux langues différentes sur la capacité d'imagerie du mouvement (vivacité des images visuelles et kinesthésiques) de 123 collégiens bilingues français/créole en situation de diglossie en Guadeloupe, en fonction de la classe d'âge des sujets
The Art of Perception: Patients Drawing Their Vestibular Schwannoma
Otorhinolaryngolog
Validating the Penn Acoustic Neuroma Quality of Life Scale in a Sample of Dutch Patients Recently Diagnosed With Vestibular Schwannoma
Otorhinolaryngolog
Intraoperative Primary Tumor Identification and Margin Assessment in Head and Neck Unknown Primary Tumors
Item does not contain fulltextOBJECTIVE: Surgical management of the unknown primary head and neck squamous cell carcinoma (UP HNSCC) remains controversial due to challenging clinical diagnosis. This study compares positron emission tomography-computed tomography (PET-CT) findings with intraoperative identification of primary tumors and compares intraoperative frozen-section margins to final histopathology. In addition, adjuvant therapy indications are provided. STUDY DESIGN: Prospective cohort study. SETTING: Academic university hospital. SUBJECTS AND METHODS: Sixty-one patients with UP HNSCC were included. Patients received PET-CT, followed by oropharyngeal transoral laser microsurgery (TLM). Margins were assessed intraoperatively using frozen sections and afterward by final histopathology. Adjuvant treatment was based on final histopathology. RESULTS: The sensitivity of localizing the primary tumor with PET-CT was 50.9% with a specificity of 82.5%. The primary tumor was found intraoperatively on frozen sections in 82% (n = 50) of patients. Five more tumors were identified on final histopathology, leading to a total of 90% (n = 55). Of the 50 intraoperatively found tumors, 98% (n = 49) had negative margins on frozen sections, and 90% (n = 45) were truly negative on final histopathology. Eighteen patients (29.5%) avoided adjuvant treatment. CONCLUSION: PET-CT localized the primary tumor in fewer than half the cases. This protocol identified 90% of primary tumors. Intraoperative frozen-section margin assessment has shown potential with a specificity of 92% compared to final histopathology. As a result, adjuvant therapy was avoided in almost one-third of our patients
Cost analysis of office-based transnasal esophagoscopy
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203314.pdf (publisher's version ) (Open Access
Office-based CO(2) laser surgery for benign and premalignant laryngeal lesions.
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220120.pdf (Publisher’s version ) (Open Access)OBJECTIVE: Patients with laryngeal pathology are often treated with CO(2) laser surgery, usually in the operating room under general anesthesia. Although office-based laser surgery using several other laser types has been investigated, prospective studies on office-based CO(2) laser surgery are scarce. Our goal was to investigate the feasibility of office-based CO(2) laser surgery for benign and premalignant laryngeal pathology by analyzing completion rate, safety, effect on voice quality, and success rate (i.e., no residual or recurrent disease). METHODS: A prospective cohort study was performed of 30 consecutive procedures. Inclusion started in June 2016 and was completed in August 2018. Adult patients with clinically benign or premalignant laryngeal lesions who could not undergo transoral laser microsurgery in the operating room under general anesthesia were included. Reasons were either contraindications for general anesthesia, previously failed therapeutic laryngoscopy under general anesthesia, and preference of a procedure under topical anesthesia by the patient. The mean follow-up was 9 months. RESULTS: Thirty procedures were performed in 27 patients (24 males) with an average age of 62 years. Twenty-nine (97%) procedures were fully completed without complications. The mean preoperative Voice Handicap Index (VHI) score (VHI 44) significantly decreased 2 months (VHI 28, P = 0.032) and 6 months (VHI 14, P < 0.001) after the procedure. Almost two-thirds of patients showed no residual or recurrent disease at their follow-up visits. CONCLUSION: Office-based CO(2) laser surgery is a feasible and safe procedure that results in significant voice-quality improvement. Almost two-thirds of patients did not require further treatment. LEVEL OF EVIDENCE: 2 Laryngoscope, 130:1503-1507, 2020.01 juni 202