Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

Gas cells for tunable diode laser absorption spectroscopy employing optical diffusers. Part 2: Integrating spheres

We have studied the effects of random laser speckle and self-mixing interference on TDLS based gas measurements made using integrating spheres. Details of the theory and TDLS apparatus are given in Part 1 of this paper and applied here to integrating spheres. Experiments have been performed using two commercial integrating spheres with diameters of 50 mm and 100 mm for the detection of methane at 1651 nm. We have calculated the expected levels of laser speckle related uncertainty, considered to be the fundamental limiting noise, and imaged subjective laser speckle in a sphere using different sized apertures. For wavelength modulation spectroscopy, noise equivalent absorbances (NEAs) of around 5x10(-5) were demonstrated in both cases, corresponding to limits of detection of 1.2 ppm methane and 0.4 ppm methane respectively. Longer-term drift was found to be at an NEA of 4x10(-4). This lies within our broad range of expectations. For a direct spectral scan with no wavelength dither, a limit of detection of 75 ppm or fractional measured power uncertainty of 3x10(-3) corresponded well with our prediction for the objective speckle uncertainty

Using integrating spheres with wavelength modulation spectroscopy: effect of pathlength distribution on 2nd harmonic signals

We have studied the effect on 2nd harmonic wavelength modulation spectroscopy of the use of integrating spheres as multipass gas cells. The gas lineshape becomes distorted at high concentrations, as a consequence of the exponential pathlength distribution of the sphere, introducing nonlinearity beyond that expected from the Beer-Lambert law. We have modelled this numerically for methane absorption at 1.651μm, with gas concentrations in the range of 0-2.5%vol in air. The results of this model compare well with experimental measurements. The nonlinearity for the 2f WMS measurements is larger than that for direct scan measurements; if this additional effect were not accounted for, the resulting error would be approximately 20% of the reading at a concentration of 2.5 %vol methane

PilT mutations lead to simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria gonorrhoeae

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73932/1/j.1365-2958.1998.00935.x.pd