8 research outputs found
La enseñanza de la psicología a través de la investigación. El niño de tres años : cómo piensa, cómo aprende y cómo se relaciona
Premios Nacionales 1999 a la Innovación EducativaEstudio realizado por un equipo de alumnos del Instituto de Enseñanza Secundaria Ricardo Bernardo de Solares, Cantábria, con el objetivo de estudiar la psicología evolutiva de los niños de tres años: cómo piensan, cómo aprenden y cómo se relacionan. El trabajo se divide en dos partes: una parte teórica en la que se estudia el niño y sus relaciones con los adultos y con otros niños; su desarrollo motor, su forma de pensar y percepción de la realidad y de la ficción, su inteligencia, su desarrollo afectivo, sus juegos y hábitos, sugerencias a los padres en lo relativo a problemas como el tartamudeo, los accidentes en el hogar y el sueño. Y una parte práctica basada en una serie de pruebas que se han realizado con niños de esta edad y sus dibujos sobre la familia y sobre un amigo.CIDEMinisterio Educación CIDEBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 Planta; 28014 Madrid; Tel. +34917748000; Fax +34917748026; [email protected]
Novel and known MYOC exon 3 mutations in an admixed Peruvian primary open-angle glaucoma population
Purpose: The aim of this study was to characterize a representative sample of the Peruvian population suffering openangle
glaucoma (OAG) with respect to the myocilin gene (MYOC) mutations, glaucoma phenotype, and ancestry for future
glaucoma risk assessment.
Methods: DNA samples from 414 unrelated Peruvian subjects, including 205 open-angle glaucoma cases (10 juvenile
glaucoma [JOAG], 19 normal-tension glaucoma [NTG], and 176 POAG) and 209 randomly sampled controls, were
screened for nucleotide changes in MYOC exon 3 by conformational sensitive gel electrophoresis (CSGE) and mutation
screening.
Results: We identified a probable causative novel MYOC missense mutation, Gly326Ser, in one POAG case and found
a consistent genotype-phenotype correlation in eight of his relatives. We also found the known causative MYOC mutation
Trp286Arg in one JOAG case and one POAG case. A known causative single base MYOC deletion, T1357, was found in
one POAG case. Two previously reported silent polymorphisms, Thr325Thr and Tyr347Tyr, were found in both the case
and the control populations. A novel missense variant, Met476Arg, was identified in two unrelated controls.
Conclusions: The screening of exon 3 of MYOC in a representative sample of 205 independent POAG patients from Peru
and 209 matched controls identified novel and previously reported mutations (both pathogenic and nonpathogenic) from
other global regions. These results reflect the complex admixture of Amerindian and Old World ancestry in urban
populations of Latin America, in general, and in Peru, in particular. It will be important to gather information about the
ancestral origin of MYOC and other POAG gene mutations to develop screening panels and risk assessment for POAG in
Peru.National Eye Institute, National Institutes
of Health, Bethesda, MD (J.E.R.), Research to Prevent
Blindness (EY011671- J.E.R.), Universidad de San Martín de
Porres Funds E10012009016, E10012009011,
E10012009027, E10012012011, Consejo Nacional de
Ciencia y Tecnología (Concytec) proyecto OAJ-2003
CropPol : a dynamic, open and global database on crop pollination
Seventy five percent of the world's food crops benefit from insect pollination. Hence, there has been increased interest in how global change drivers impact this critical ecosystem service. Because standardized data on crop pollination are rarely available, we are limited in our capacity to understand the variation in pollination benefits to crop yield, as well as to anticipate changes in this service, develop predictions, and inform management actions. Here, we present CropPol, a dynamic, open, and global database on crop pollination. It contains measurements recorded from 202 crop studies, covering 3,394 field observations, 2,552 yield measurements (i.e., berry mass, number of fruits, and fruit density [kg/ha], among others), and 47,752 insect records from 48 commercial crops distributed around the globe. CropPol comprises 32 of the 87 leading global crops and commodities that are pollinator dependent. Malus domestica is the most represented crop (32 studies), followed by Brassica napus (22 studies), Vaccinium corymbosum (13 studies), and Citrullus lanatus (12 studies). The most abundant pollinator guilds recorded are honey bees (34.22% counts), bumblebees (19.19%), flies other than Syrphidae and Bombyliidae (13.18%), other wild bees (13.13%), beetles (10.97%), Syrphidae (4.87%), and Bombyliidae (0.05%). Locations comprise 34 countries distributed among Europe (76 studies), North America (60), Latin America and the Caribbean (29), Asia (20), Oceania (10), and Africa (7). Sampling spans three decades and is concentrated on 2001-2005 (21 studies), 2006-2010 (40), 2011-2015 (88), and 2016-2020 (50). This is the most comprehensive open global data set on measurements of crop flower visitors, crop pollinators and pollination to date, and we encourage researchers to add more datasets to this database in the future. This data set is released for non-commercial use only. Credits should be given to this paper (i.e., proper citation), and the products generated with this database should be shared under the same license terms (CC BY-NC-SA)
The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)—has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity