2,112 research outputs found

    Developing Partnerships for Academic Data Science Consulting and Collaboration Units

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    Data science consulting and collaboration units (DSUs) are core infrastructure for research at universities. Activities span data management, study design, data analysis, data visualization, predictive modelling, preparing reports, manuscript writing and advising on statistical methods and may include an experiential or teaching component. Partnerships are needed for a thriving DSU as an active part of the larger university network. Guidance for identifying, developing and managing successful partnerships for DSUs can be summarized in six rules: (1) align with institutional strategic plans, (2) cultivate partnerships that fit your mission, (3) ensure sustainability and prepare for growth, (4) define clear expectations in a partnership agreement, (5) communicate and (6) expect the unexpected. While these rules are not exhaustive, they are derived from experiences in a diverse set of DSUs, which vary by administrative home, mission, staffing and funding model. As examples in this paper illustrate, these rules can be adapted to different organizational models for DSUs. Clear expectations in partnership agreements are essential for high quality and consistent collaborations and address core activities, duration, staffing, cost and evaluation. A DSU is an organizational asset that should involve thoughtful investment if the institution is to gain real value

    Extending the Research Data Toolkit: Data Curation Primers

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    Niche and proprietary data formats used in cutting-edge research and technology have specific curation considerations and challenges. The increased demand for subject liaisons, library archivists, and digital curators to curate this variety of data types created locally at an institution or organization poses difficulties. Subject liaisons possess discipline knowledge and expertise for a given domain or discipline and digital curation experts know how to properly steward data assets generally. Yet, a gap often exists between the expertise available within the organization and local curation needs. While many institutions and organizations have expertise in certain domains and areas, oftentimes the heterogeneous data types received for deposit extend beyond this expertise. Additionally, evolving research methods and new, cutting-edge technology used in research often result in unfamiliar and niche data formats received for deposit. Knowing how to ‘get-started’ in curating these file types and formats can be a particular challenge. To address this need, the data curation community have been developing a new set of tools – data curation primers. These primers are evolving documents that detail a specific subject, disciplinary area or curation task, and that can be used as a reference or jump-start to curating research data. This paper will provide background on the data curation primers and their content detail the process of their development, highlight the data curation primers published to date, emphasize how curators can incorporate these resources into workflows, and show curators how they can get involved and share their own expertise

    Launching the Data Curation Network

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    Presentation at the 2018 International Digital Curation Conference (IDCC) in Barcelona, Spain.“Launching the Data curation Network: A cross-institutional staffing model for curating research data” funded 2018-2021 by the Alfred P. Sloan Foundation grant G-2018-10072

    Data Curation Network: Developing and Scaling Research Data Management

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    Presentation at the NISO Virtual Conference: Open Data Projects.“Launching the Data curation Network: A cross-institutional staffing model for curating research data” funded 2018-2021 by the Alfred P. Sloan Foundation grant G-2018-10072

    Implementing a Cross-Institutional Staffing Model for Curating Research Data

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    Poster presented at the Research Data Alliance (RDA) 11th Plenary in Berlin, Germany.“Launching the Data curation Network: A cross-institutional staffing model for curating research data” funded 2018-2021 by the Alfred P. Sloan Foundation grant G-2018-10072

    Launching the Data Curation Network

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    Presentation at the 2018 Research Data Access and Preservation (RDAP) Summit in Chicago, IL.“Launching the Data curation Network: A cross-institutional staffing model for curating research data” funded 2018-2021 by the Alfred P. Sloan Foundation grant G-2018-10072

    Data Curation Network: A Cross-Institutional Staffing Model for Curating Research Data

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    Funders increasingly require that data sets arising from sponsored research must be preserved and shared, and many publishers either require or encourage that data sets accompanying articles are made available through a publicly accessible repository. Additionally, many researchers wish to make their data available regardless of funder requirements both to enhance their impact and also to propel the concept of open science. However, the data curation activities that support these preservation and sharing activities are costly, requiring advanced curation practices, training, specific technical competencies, and relevant subject expertise. Few colleges or universities will be able to hire and sustain all of the data curation expertise locally that its researchers will require, and even those with the means to do more will benefit from a collective approach that will allow them to supplement at peak times, access specialized capacity when infrequently-curated types arise, and stabilize service levels to account for local staff transition, such as during turn-over periods. The Data Curation Network (DCN) provides a solution for partners of all sizes to develop or to supplement local curation expertise with the expertise of a resilient, distributed network, and creates a funding stream to both sustain central services and support expansion of distributed expertise over time. This paper presents our next steps for piloting the DCN, scheduled to launch in the spring of 2018 across nine partner institutions. Our implementation plan is based on planning phase research performed from 2016-2017 that monitored the types, disciplines, frequency, and curation needs of data sets passing through the curation services at the six planning phase institutions. Our DCN implementation plan includes a well-coordinated and tiered staffing model, a technology-agnostic submission workflow, standardized curation procedures, and a sustainability approach that will allow the DCN to prevail beyond the grant-supported implementation phase as a curation-as-service model

    Data Curation Services, Together!

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    November 2018 RDAP Webinar presentation.“Launching the Data curation Network: A cross-institutional staffing model for curating research data” funded 2018-2021 by the Alfred P. Sloan Foundation grant G-2018-10072

    A View of Tropical Cyclones from Above: The Tropical Cyclone Intensity Experiment

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    Tropical cyclone (TC) outflow and its relationship to TC intensity change and structure were investigated in the Office of Naval Research Tropical Cyclone Intensity (TCI) field program during 2015 using dropsondes deployed from the innovative new High-Definition Sounding System (HDSS) and remotely sensed observations from the Hurricane Imaging Radiometer (HIRAD), both on board the NASA WB-57 that flew in the lower stratosphere. Three noteworthy hurricanes were intensively observed with unprecedented horizontal resolution: Joaquin in the Atlantic and Marty and Patricia in the eastern North Pacific. Nearly 800 dropsondes were deployed from the WB-57 flight level of ∼60,000 ft (∼18 km), recording atmospheric conditions from the lower stratosphere to the surface, while HIRAD measured the surface winds in a 50-km-wide swath with a horizontal resolution of 2 km. Dropsonde transects with 4–10-km spacing through the inner cores of Hurricanes Patricia, Joaquin, and Marty depict the large horizontal and vertical gradients in winds and thermodynamic properties. An innovative technique utilizing GPS positions of the HDSS reveals the vortex tilt in detail not possible before. In four TCI flights over Joaquin, systematic measurements of a major hurricane’s outflow layer were made at high spatial resolution for the first time. Dropsondes deployed at 4-km intervals as the WB-57 flew over the center of Hurricane Patricia reveal in unprecedented detail the inner-core structure and upper-tropospheric outflow associated with this historic hurricane. Analyses and numerical modeling studies are in progress to understand and predict the complex factors that influenced Joaquin’s and Patricia’s unusual intensity changes

    Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico

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    The mitochondrial free radical theory of aging (mFRTA) implicates Reactive Oxygen Species (ROS)-induced mutations of mitochondrial DNA (mtDNA) as a major cause of aging. However, fifty years after its inception, several of its premises are intensely debated. Much of this uncertainty is due to the large range of values in the reported experimental data, for example on oxidative damage and mutational burden in mtDNA. This is in part due to limitations with available measurement technologies. Here we show that sample preparations in some assays necessitating high dilution of DNA (single molecule level) may introduce significant statistical variability. Adding to this complexity is the intrinsically stochastic nature of cellular processes, which manifests in cells from the same tissue harboring varying mutation load. In conjunction, these random elements make the determination of the underlying mutation dynamics extremely challenging. Our in silico stochastic study reveals the effect of coupling the experimental variability and the intrinsic stochasticity of aging process in some of the reported experimental data. We also show that the stochastic nature of a de novo point mutation generated during embryonic development is a major contributor of different mutation burdens in the individuals of mouse population. Analysis of simulation results leads to several new insights on the relevance of mutation stochasticity in the context of dividing tissues and the plausibility of ROS ”vicious cycle” hypothesis
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