A Proposal for Coordinating Internships as an Alliance between Education and the Productive Sector

El trabajo que se presenta tiene por finalidad proponer la Coordinación de Prácticas Profesionales en el Programa Ciencias Económicas y Sociales del Núcleo Costa Oriental del Lago de la Universidad del Zulia. A través de las prácticas profesionales se pretende familiarizar al estudiante con los ambientes, actividades y tareas propias de la profesión, así como también con los instrumentos y sus diferentes campos de acción, además de los conocimientos necesarios para desarrollar la capacidad creativa e innovadora, de manera que pueda hacer frente a la realidad del país, participando en la dinámica de los procesos económicos, políticos y social-ambiental. Se espera que con la coordinación propuesta se logre la integración de la universidad con el sector productivo en la Costa Oriental del Lago en el estado ZuliaThe work presented proposes a Coordination for Internships in the Economic and Social Sciences Program at the University of Zulia, East Lake Coast campus. Through internships, students will get to know the environments, activities and tasks of the profession, as well as the instruments and different fields of action, in addition to the knowledge needed to develop creative and innovative capacity, so that they can deal with the reality of the country, participating in the dynamic of economic, political and social-environmental processes. It is hoped that through the proposed coordination, the university will be able to integrate with the productive sector on the East Lake Coast in the State of Zuli

Innovaciones curriculares para mejoras sociolaborales en Venezuela. Cuestiones culturales en la formación del administrador

La Formación del Administrador en Venezuela es la parte del currículo universitario que media entre la teoría y la práctica. En este artículo se pretende realizar una revisión lo más completa y exhaustiva posible de las nuevas relaciones universidad-mercado laboral y del currículo innovador para la formación del administrador. Se concluye que la transformación curricular debe estar en hacer cambios en los contenidos programáticos o formativos a fin de que los estudiantes universitarios tengan la mejor y actualizada formación posible en su área, haciendo que la transferencia de conocimiento se fortalezca y los egresados sean agentes de cambio.A Formação do Administrador na Venezuela é a parte do currículo universitário que estabelece a relação entre a teoria e a prática. Este artigo tem como objetivo realizar uma revisão o mais completa e exaustiva possível das novas relações universidade-mercado laboral e do currículo inovador para a formação do administrador. Conclui-se que a transformação curricular deve realizar-se através de alterações nos conteúdos programáticos ou formativos para que os estudantes universitários tenham a melhor e mais atualizada formação possível na sua área, fazendo com que a transferência de conhecimento se fortaleça e os licenciados se assumam como agentes de mudançaManager Training in Venezuela is the part of the university curriculum that mediates between theory and practice. This article aims to make a review as complete and comprehensive as possible of the new university-labor market relations and of the innovative curriculum for the training of the administrator. We conclude that the curriculum transformation should be on making changes in program or training content so that college students have the best possible and updated education in their area, strengthening the transfer of knowledge and stimulating graduates as agents of change

A rare missense mutation in a type 2 diabetes patient decreases the transcriptional activity of human sterol regulatory element binding protein-1

11 pages, 3figures, 1 table.-PMID: 16429400 [PubMed]Sterol regulatory element binding protein 1 (SREBP-1) transcription factors play a key role in energy homeostasis by regulating genes involved in both carbohydrate and lipid metabolism, and in adipocyte differentiation. The 5' end of the mRNA-encoding SREBP-1 exists in two forms, designated 1a and 1c. The divergence results from the use of two transcription start sites that produce two separate 5' exons, each of which is spliced to a common exon 2. Mutations in the sterol regulatory element binding protein gene (SREBF)-1 may contribute to insulin resistance states. However, the variants described to date do not affect the SREBP function. In this study, we investigated the functional consequences of a novel missense mutation common to both SREBP-1 isoforms identified in a Spanish Type 2 diabetic patient (c.677C>T, SREBP-1a p.T226M; c.605C>T, SREBP-1c p.T202M). Using reporter gene analysis and electrophoretic mobility shift assays, we found that this variant impaires the transcriptional activity and reduces DNA binding ability despite its comparable protein stability to the wild-type SREBP-1. This decreased activity impaires the expression of known downstream targets, such as the LDL receptor and fatty acid synthase genes. Our findings suggest that the threonine residue and/or surrounding region play an important role in the SREBP-1 functionThis study was supported by grants from Instituto de Salud Carlos III, Red de Centros (RCMN) C03/08, and from Ministerio de Educación y Ciencia (SAF2003-01262). S.V. is supported by a fellowship from Consejo Superior de Investigaciones Científicas I3P-BPD2001-1.Peer reviewe

Validation of the Spanish version of the Problem Areas in Diabetes (PAID-SP) Scale

This study aimed to assess the psychometric properties of the Spanish version of the Problem Areas in Diabetes (PAID-SP) Scale. Data were collected from patients with type 1 and type 2 diabetes. The findings suggested that the PAID-SP is a reliable and valid measure of diabetes-specific emotional problems

Caries dental en diabéticos tipo 1: Influencia de factores sistémicos de la enfermedad en la instauración de la caries dental

Objetivos: La diabetes mellitus es una de las enfermedades crónicas más prevalentes en población general. Se presenta un estudio que pretende evaluar la presencia de caries en los pacientes diabéticos tipo 1. El objetivo específico era comprobar si había o no mayor incidencia de caries en diabéticos tipo 1 comparándolos con un grupo de individuos no diabéticos. También, se comprobó la relación con las tasas de flujo salival y con los factores propios de la enfermedad como el grado de control metabólico, el tiempo de evolución de la enfermedad y la existencia de complicaciones crónicas. Diseño del estudio: Se estudiaron 90 diabéticos tipo 1 de edades comprendidas entre los 18 y los 50 años de edad y un grupo de pacientes controles no diabéticos pareados por edad y sexo. Se realizó una exploración visual y táctil, en todos los dientes de los sujetos explorados. Se tuvo en cuenta el grado de la higiene oral mediante el índice de placa de O'Leary, y se estudiaron las tasas de saliva basal y estimulada en ambos grupos. En el grupo diabético se relaciono con el control de la enfermedad mediante la obtención de la media de la hemoglobina glicosilada (HbA1c) de los dos años previos a la exploración, así como la evolución de su enfermedad en años y la existencia de complicaciones como neuropatía diabética o retinopatía. Resultados: Bajo similares condiciones de higiene oral y de flujo salival, el grupo diabético resultó tener una incidencia de caries mayor que el grupo control (p<0.05). Asimismo, al estudiar específicamente al grupo diabético, ni el control metabólico de la enfermedad, ni la evolución de la enfermedad, ni la existencia de complicaciones de la diabetes tenían influencia en la instauración de caries dental. Conclusiones: Se sugiere que habría que estudiar factores cualitativos salivales que explicasen esta mayor incidencia de caries en los diabéticos.Objectives: Diabetes mellitus is one of the most common chronic diseases in the general population. A study is made of the presence of caries in type 1 diabetic patients. The specific aim was to determine whether such patients present a greater incidence of dental caries than non-diabetic individuals. An evaluation was also made of the relationship of caries to salivary flow and to factors inherent to the disease such as the degree of metabolic control, the duration of diabetes, and the existence of chronic complications. Study design: The study comprised 90 type 1 diabetics between 18 and 50 years of age, and a group of non-diabetic controls matched for age and sex. Visual and tactile exploration of the dentition was carried out in all cases. Oral hygiene was rated based on the O'Leary plaque index, and basal (unstimulated) and stimulated salivary flow were evaluated in both groups. In the diabetic group, correlations were established with disease control based on the mean glycosylated hemoglobin (HbA1c) value corresponding to the two years prior to examination; evolution of the disease in years; and the existence of complications such as diabetic neuropathy or retinopathy. Results: Under similar conditions of oral hygiene and salivary flow, the diabetic group showed a higher incidence of caries than the control group (p<0.05). Likewise, on specifically analyzing the diabetic group, metabolic control of the disease, the duration of diabetes, and the existence of complications of the disease exerted an influence upon the development of dental caries. Conclusions: Qualitative salivary studies are advised to better account for this increased incidence of caries in the diabetic population

Efect of periodontal disease and non surgical periodontal treatment on C-reactive protein. Evaluation of type 1 diabetic patient.

Objectives: The purpose of this study was to analyze how anti-infectious periodontal treatment affects C reactive protein (CRP) values in patients with type 1 diabetes, and correlate baseline CRP levels with periodontal disease severity. Study Design: A cohort of fifty three subjects with type 1 diabetes and moderate to severe periodontitis were recruited. Periodontal parameters were measured, and blood samples were obtained to evaluate high-sensitivity C-reactive protein (hs-CRP). Group 1 was treated with scaling, root planning, and systemic administration of doxycycline. Group 2 received only scaling and root planning. Results: Hs-CRP was reduced after periodontal treatment in group 1 (-0.22 mg/l) and 2 (-0.21 mg/l ) but this reduction was not statistically significant, even in the patients with the best response to periodontal treatment. However, significant correlation appeared between hs-CRP and mean probing pocket depth (PPD) (p=0, 01) and mean clinical attachment level (CAL) (p=0,03). Conclusions: Non-surgical periodontal treatment couldn¿t reduce hs-CRP values, however, it was found an asso- ciation between advanced periodontitis and elevated blood hs-CRP levels in patients with type 1 diabetes. It can be speculated that periodontal disease increases production of pro-inflammatory mediators in patients with type 1 diabetes, but other producing sources of these pro-inflammatory substances may exist

A Scalable Reduced-Complexity Compression of Hyperspectral Remote Sensing Images Using Deep Learning

Two key hurdles to the adoption of Machine Learning (ML) techniques in hyperspectral data compression are computational complexity and scalability for large numbers of bands. These are due to the limited computing capacity available in remote sensing platforms and the high computational cost of compression algorithms for hyperspectral data, especially when the number of bands is large. To address these issues, a channel clusterisation strategy is proposed, which reduces the computational demands of learned compression methods for real scenarios and is scalable for different sources of data with varying numbers of bands. The proposed method is compatible with an embedded implementation for state-of-the-art on board hardware, a first for a ML hyperspectral data compression method. In terms of coding performance, our proposal surpasses established lossy methods such as JPEG 2000 preceded by a spectral Karhunen-Loève Transform (KLT), in clusters of 3 to 7 bands, achieving a PSNR improvement of, on average, 9 dB for AVIRIS and 3 dB for Hyperion images

Type 1 diabetes mellitus and periodontal disease : relationship to different clinical variables

Objective: This study is designed to evaluate the frequency of periodontal disease in a group of patients with type 1 diabetes mellitus and how this relates with diabetes metabolic control, duration of diabetes, and presence of diabetic complications. Methods: A comparison was made of periodontal parameters (plaque index, bleeding index, pocket depth and attachment loss) in a group of diabetic patients (n=90) versus a group of non-diabetics (n=90). Logistic regression analysis was performed to evaluate relationship between periodontal parameters and degree of metabolic control, the duration of the disease, and the appearance of complications. Results: Diabetics had greater bleeding index (p<0.01), deeper periodontal pockets (p<0.01) and more periodontal attachment loss (p<0.01) than non-diabetics. Deficient metabolic control and presence of diabetic complication were associated with higher bleeding index and pocket depth (p?0.02). Conclusions: Patients with type 1 diabetes appear to show increased periodontal disease susceptibility, particularly those with poorer metabolic control or with diabetic complications

Dental caries in type 1 diabetics : influence of systemic factors of the disease upon the development of dental caries

Objectives: Diabetes mellitus is one of the most common chronic diseases in the general population. A study is made of the presence of caries in type 1 diabetic patients. The specific aim was to determine whether such patients present a greater incidence of dental caries than non-diabetic individuals. An evaluation was also made of the relationship of caries to salivary flow and to factors inherent to the disease such as the degree of metabolic control, the duration of diabetes, and the existence of chronic complications. Study design: The study comprised 90 type 1 diabetics between 18 and 50 years of age, and a group of non-diabetic controls matched for age and sex. Visual and tactile exploration of the dentition was carried out in all cases. Oral hygiene was rated based on the O?Leary plaque index, and basal (unstimulated) and stimulated salivary flow were evaluated in both groups. In the diabetic group, correlations were established with disease control based on the mean glycosylated hemoglobin (HbA1c) value corresponding to the two years prior to examination; evolution of the disease in years; and the existence of complications such as diabetic neuropathy or retinopathy. Results: Under similar conditions of oral hygiene and salivary flow, the diabetic group showed a higher incidence of caries than the control group (p<0.05). Likewise, on specifically analyzing the diabetic group, metabolic control of the disease, the duration of diabetes, and the existence of complications of the disease exerted an influence upon the development of dental caries. Conclusions: Qualitative salivary studies are advised to better account for this increased incidence of caries in the diabetic population