STB-White

The final design of a hypersonic, SCRAMjet research aircraft, which is to be dropped from a carrier plane, is considered. Topics such as propulsion systems, aerodynamics, component weight analysis, and aircraft design with waverider analyses are stressed with smaller emphasis placed on aircraft systems such as cockpit design and landing gear configurations. Propulsion systems include analysis of the turbofanramjet for acceleration to low hypersonic speed (Mach 6.0) and analysis of the SCRAMjets themselves to carry the aircraft to Mach 10.0. Both analyses include the use of liquid hydrogen as fuel. Inlet design for both propulsion systems is analyzed as well. Aerodynamic properties are found using empirical and theoretical formulas for lift and drag on delta-wing aircraft. The aircraft design involves the integration of all preliminary studies into a modified waverider configuration

Delayed Striate Cortical Activation during Spatial Attention

AbstractRecordings of event-related potentials (ERPs) and event-related magnetic fields (ERMFs) were combined with functional magnetic resonance imaging (fMRI) to study visual cortical activity in humans during spatial attention. While subjects attended selectively to stimulus arrays in one visual field, fMRI revealed stimulus-related activations in the contralateral primary visual cortex and in multiple extrastriate areas. ERP and ERMF recordings showed that attention did not affect the initial evoked response at 60–90 ms poststimulus that was localized to primary cortex, but a similarly localized late response at 140–250 ms was enhanced to attended stimuli. These findings provide evidence that the primary visual cortex participates in the selective processing of attended stimuli by means of delayed feedback from higher visual-cortical areas

The Grizzly, April 29, 1988

Alcohol Policy Discussed • Honorability Sought at Ursinus • Meet McCurdy! • Urisnus\u27 Own Oscar Winners • Come One, Come All! • Letters: Plagiarist Re-admitted?; Casey Causes Changes; Blast From the Past; Alcohol Education • Band to Perform • That Staiger Chemistry Not at all Overdue • PA Dutch Parsons • Emeritus Williamson • U.C. to Take on Trenton State in Lax Showdown Tonight • Baseball on 6-game Win Streak • Men Backhand W.M. and Albright for U.C. Victory • Tennis Women End Season 6-4 • New Football Mentor • Goldberg Finds Student Athletes • Young\u27s Notes for You • Medieval Fest at College Aids Handicapped • Final Exam Schedulehttps://digitalcommons.ursinus.edu/grizzlynews/1213/thumbnail.jp

Prohibiting alcohol sales during the coronavirus disease 2019 pandemic has positive effects on health services in South Africa

Reuter H, Jenkins LS, De Jong M, Reid S, Vonk M. Prohibiting alcohol sales during the coronavirus disease 2019 pandemic has positive effects on health services in South Africa. Afr J Prm Health Care Fam Med. 2020;12(1), a2528.As the coronavirus disease 2019 (Covid-19) pandemic evolves globally, we are realising its impact on communities from the disease itself and the measures being taken to limit infection spread. In South Africa (SA), 62 300 adults die annually from alcohol-attributable causes. Alcohol-related harm can be reduced by interventions, such as taxation, government monopolising retail sales, outlet density restriction, hours of sales and an advertising ban. To mitigate the impact of the Covid-19 pandemic, SA instituted a lockdown that also prohibited alcohol sales. This led to a sharp reduction in unnatural deaths in the country from 800–1000/week to around 400/week during the lockdown. We reviewed three 2-week periods at a large rural regional hospital: Before Covid-19 (February), during social distancing (March) and during lockdown with alcohol ban (April). A dramatic drop in patient numbers from 145 to 64 (55.8%) because of assault, from 207 to 83 (59.9%) because of accidents, from 463 to 188 (59.4%) because of other injuries and from 12 to 1 (91.6%) because of sexual assaults was observed during the first 2 weeks of lockdown. As healthcare professionals, we need to advocate for the ban to remain until the crisis is over to ensure that health services can concentrate on Covid-19 and other patients. We encourage other African states to follow suit and implement alcohol restrictions as a mechanism to free up health services. We see this as an encouragement to lobby for a new normal around alco

The Grizzly, October 2, 1987

Academic Standards Set • Potential Pledges Prepare for New State Policy • Student Accosted on Main St. • Letters: Call to Remember Yom Kippur; Paint This!; Response to Student Apathy • What\u27s a Bork? Find out! • Graduate Study Abroad Offered • Ursinus is Everywhere • Super Sunday\u27s Last Chance • Dance Forum Gets Down • Bears Won! • Bears Set Spikes • Soccer\u27s Record: 4-3 • Hockey Handed First Setback • Bear Pack Continues Winning • Waged War Won by Phils • O\u27Donohue Claims Honors • Concert Benefit Scheduled • Dated Parties Hosed • No Lapse in New Floydhttps://digitalcommons.ursinus.edu/grizzlynews/1194/thumbnail.jp

The Grizzly, March 25, 1988

Alcohol Abuse Abounds • Abortion Forum Caused Little Racket • Conwell is Here! • Selected Speakers: Berry and Connolly • Letters: Women More Than Miffed; Task Force Wants You; Applause to Participants; We Want Service, Too!; Track Awards Noted • Easter Reflections on Zacharias • Developing Student Life • Major Math • Jazz! • MAC Honors Outstanding Student-Athletes • Lady Bears Steel Show • Baseball Pitches Win • Bears Make Tracks • Lax is Ready! • Gym-Nastics • Ursinus Men Strut Their Stuff • Berry: Up Close and Personal • Organ Virtuoso to Perform • McCullough\u27s Safety Tips • Rally Round Nally • Now and Zen Up and Coming • The Zoo\u27s the News • Dying Boy, 6 Needs Helphttps://digitalcommons.ursinus.edu/grizzlynews/1209/thumbnail.jp

The Grizzly, December 4, 1987

Get a Grip on Handel • Aggressive Couple to Move • Letter: USGA Concerned with Fund Allocation • Wismer Move Official • Christmas Festivities Planned for Campus • Musser Plans Dinner • Ursinus Campus: Not What it Used to Be • Matters Successful • New Attitude Turns Ladies\u27 Fortune • Ursinus Welcomes Chang Back to College Campus • New Club in Spring • Home Streak Making Hoopla • Take a Realistic Look at the Job Market • All-American Honors for Field Hockey\u27s Dicton and Johnson • V-Baller Honored • Gymnasts Open Season • Scholars Gain All-ECAC • Walk This Way, Says Davidson • Concert Last in Forum Series • Don we Now Our Football Apparel • Dee Shares Business Ventures • Springsteen Sings In New Style • Limited Firebreathing for Lionarons\u27 Dragons • Final Exam Schedulehttps://digitalcommons.ursinus.edu/grizzlynews/1201/thumbnail.jp

In Vitro and In Vivo Neurotoxicity of Prion Protein Oligomers

The mechanisms underlying prion-linked neurodegeneration remain to be elucidated, despite several recent advances in this field. Herein, we show that soluble, low molecular weight oligomers of the full-length prion protein (PrP), which possess characteristics of PrP to PrPsc conversion intermediates such as partial protease resistance, are neurotoxic in vitro on primary cultures of neurons and in vivo after subcortical stereotaxic injection. Monomeric PrP was not toxic. Insoluble, fibrillar forms of PrP exhibited no toxicity in vitro and were less toxic than their oligomeric counterparts in vivo. The toxicity was independent of PrP expression in the neurons both in vitro and in vivo for the PrP oligomers and in vivo for the PrP fibrils. Rescue experiments with antibodies showed that the exposure of the hydrophobic stretch of PrP at the oligomeric surface was necessary for toxicity. This study identifies toxic PrP species in vivo. It shows that PrP-induced neurodegeneration shares common mechanisms with other brain amyloidoses like Alzheimer disease and opens new avenues for neuroprotective intervention strategies of prion diseases targeting PrP oligomers

The Grizzly, November 20, 1987

Outdoor Graduation Possible • Judo Flip Flopped • Kamens Won\u27t \u27Drink the Water\u27 • Akin Probes Goals for Middle States • Letters: Director of Security Concerned; Mail Malady; Physical Activity Needed • Myth Myths Explained in Fourth Forum • Messiah to Celebrate 50th Year • Volkmer Outshines Pooch? • Promising Season to Start for Basketball • Football Players make Conference Team • Lady \u27Mers Victorious • Grizzly Wrap Up • Lady Grizzlies Begin Season • Government Officials Speak at Conference • Bad Day for Team • Out of the States : Into Africa • Apartheid: The Economic Impact • The Attention-Getterhttps://digitalcommons.ursinus.edu/grizzlynews/1200/thumbnail.jp

The Grizzly, October 16, 1987

Campus Crackdown Affects All • Police to Halt Under-Age Drinking • Rafuse Paint Crew: Loud, Leering and Surly? • Students Study Abroad • Musser Returns to Dark Ages • Letter: Grizzly Errs • G.E. Attends U.C. Luncheon • The International Job Scene • Commuter Communication Gap • Bears Hope for Winning Season • Soccer Sinks Washington • Athlete of the Week: Walder Forwards Record • Meet the 1987 Homecoming Queen Candidates • Football to Face Gettysburg • Hockey Halted by West Chester • Myrin Catalog System On Line • Busie Body Needs a Bodyhttps://digitalcommons.ursinus.edu/grizzlynews/1196/thumbnail.jp