The Grizzly, March 31, 1989

This is an April Fool\u27s satire edition of the Grizzly newspaper entitled The Goofley.https://digitalcommons.ursinus.edu/grizzlynews/1233/thumbnail.jp

The Grizzly, April 22, 1988

Is There \u27Lite\u27 at the End of the Tunnel? • Speaker Remembers Holocaust • Ursinus Women Catch \u27Creeps\u27 • Letter: Policy Needs Student Input • Middle East Conflict Discussed • Athletic Banquet • Much Ado: An Uproarious Must See • Students Present Papers • Men\u27s Tennis Serves Notice That They\u27re a Team to Reckon With • Tittlemayer Leads UC Baseball in their Pitch for the Playoffs • West Chester Win Puts UC Lax Back on Track • The Grizzly\u27s Senior Spotlight Salutes Caffrey • Track Grabs Big Win • UCC Heritage Day • Scholars Chosenhttps://digitalcommons.ursinus.edu/grizzlynews/1212/thumbnail.jp

The Grizzly, November 10, 1989

Wismer Staff Pleads Innocence: Verdict? • Museum Safe and Sound • Dinner for Visitors • Letters: Get to the Point!; GDI Tired of Greek Rights at U.C.; Pro-Life Prof Speaks for Babies • U.C.\u27s Very Vibrant Voices • Opinion: Global Warming • Promoting Condom Sensehttps://digitalcommons.ursinus.edu/grizzlynews/1246/thumbnail.jp

The Grizzly, April 29, 1988

Alcohol Policy Discussed • Honorability Sought at Ursinus • Meet McCurdy! • Urisnus\u27 Own Oscar Winners • Come One, Come All! • Letters: Plagiarist Re-admitted?; Casey Causes Changes; Blast From the Past; Alcohol Education • Band to Perform • That Staiger Chemistry Not at all Overdue • PA Dutch Parsons • Emeritus Williamson • U.C. to Take on Trenton State in Lax Showdown Tonight • Baseball on 6-game Win Streak • Men Backhand W.M. and Albright for U.C. Victory • Tennis Women End Season 6-4 • New Football Mentor • Goldberg Finds Student Athletes • Young\u27s Notes for You • Medieval Fest at College Aids Handicapped • Final Exam Schedulehttps://digitalcommons.ursinus.edu/grizzlynews/1213/thumbnail.jp

The Grizzly, September 1, 1989

U.C. Transition • Diverse Freshman Diverge on Ursinus • Letter: Frosh Finds Staff Discourteous • Corson Facelift Removes Moles • Bright Moments Jazz Steams Bomberger Night • Bio Grants Lend Expansion • Lax: National Champs! • Wood Takes Titles • Lacrosse Coaches Retire • Lady Bears: Few, But Strong • Bears to Repeat • St. Joe\u27s / U.C. MBA Still O.K. • Academic Year Openedhttps://digitalcommons.ursinus.edu/grizzlynews/1238/thumbnail.jp

The Grizzly, April 21, 1989

Spring Weekend a Whopper! • Ours Nouveau • Sunday\u27s Reception Huge Success • Letter: Shed Miniskirts for Spandex • Heritage Day • Berman Roofing Top Hat Affair • \u27Packers Hike Hick Hills • Ground Round: Super Service • Running\u27s More Than Just Winning • Spring Sports: Hot and Cold • Mr. Ursinus a Whomping Good Time!https://digitalcommons.ursinus.edu/grizzlynews/1236/thumbnail.jp

The Grizzly, October 23, 1987

Middle States to Evaluate the Ursinus Community • Gilmore Tops Successful Homecoming • Greek Life Threatened • Letters: Pledging Restrictions Destructive?; Professor Supports Religious Understanding • Hot Entertainment to Hit Ursinus • As We Begin the World • Dance Forum Dazzles Audience • Scholars Offer Variety • Old Wine in New Bottles • Speech Exam Offered • Surf\u27s Up for the Lady Bears • Ursinus Athletes and Coach Win at Homecoming • This Run\u27s for you Vince • Athlete of the Week: Football\u27s Glenn Worgan • Grizzlies to Hang Tough • Choral Groups to Entertain Ursinus • WVOU is Back! • Ritter Center: A Beehive of Busyness the Busie Body to Premiere Oct. 29 • Owners Strike Backhttps://digitalcommons.ursinus.edu/grizzlynews/1197/thumbnail.jp

Pro-fibrotic effects of CCL18 on human lung fibroblasts are mediated via CCR6

Background: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown origin, with a median patient survival time of ~3 years after diagnosis without anti-fibrotic therapy. It is characterized by progressive fibrosis indicated by increased collagen deposition and high numbers of fibroblasts in the lung. It has been demonstrated that CCL18 induces collagen and αSMA synthesis in fibroblasts. We aimed to identify the CCL18 receptor responsible for its pro-fibrotic activities. Methods: We used a random phage display library to screen for potential CCL18-binding peptides, demonstrated its expression in human lungs and fibroblast lines by PCR and immunostaining and verified its function in cell lines. Results: We identified CCR6 (CD196) as a CCL18 receptor and found its expression in fibrotic lung tissue and lung fibroblast lines derived from fibrotic lungs, but it was almost absent in control lines and tissue. CCL18 induced receptor internalization in a CCR6-overexpressing cell line. CCR6 blockade in primary human lung fibroblasts reduced CCL18-induced FGF2 release as well as collagen-1 and αSMA expression. Knockdown of CCR6 in a mouse fibroblast cell line abolished the induction of collagen and α-smooth muscle actin expression. Conclusion: Our data indicate that CCL18 triggers pro-fibrotic processes via CCR6, highlighting its role in fibrogenesi

The Grizzly, September 23, 1988

Sexual Harassment: Battling Sex Roles • Bridging the Gap • Parents\u27 Day Fair Promising • Letter: U.C. Knows Worth • U.C. Loses in Ratings Game • Sporting Theatre • Fife Marches to Math Cadence • Volleyball Hits Target • Soccer on Winning Streak • Lady Bears Back in Groove Again • Bears Lose Second Straight • Sports Exhibit Openshttps://digitalcommons.ursinus.edu/grizzlynews/1218/thumbnail.jp

The Grizzly, March 3, 1989

Quad Asbestos Cover-Up? • UC Lip-synching Talents Shown at Airband • Letters: Klee Clears Clutter; Fondots Tepid About Water; Students Concerned • Bond is Back! • Isaac\u27s Astounds Aussie • Men\u27s Indoor Ready for Mainstream • Youthful Bears Swim to 3rd • Senior Trio Leads Ursinus • McGowan\u27s Courage Inspiring • Bears End Season Upbeat • Send North Up The River?https://digitalcommons.ursinus.edu/grizzlynews/1231/thumbnail.jp