Colección Histórica Cubana y Americana, dirigida por Emilio Roig de Leuchsenring, Historiador de la Ciudad de la Habana.

Se trata de la Publicación más completa hasta ahora de las poesías de José María Heredia y Heredia con semblanzas y anotaciones a pie de página hechas por los principales heredianos cubanos de principios del siglo XX: Emilio Roig de Leuchsenring, Francisco González del Valle. Una copia del documento se encuentra en la Biblioteca Virtual “Miguel de Cervantes”, www.cervantesvirtual.co

Homenaje de la Ciudad de la Habana en el centenario de la Muerte de Heredia (1839-1939) Vol. I

Se trata de la Publicación más completa hasta ahora de las poesías de José María Heredia y Heredia con semblanzas y anotaciones a pie de página hechas por los principales heredianos cubanos de principios del siglo XX: Emilio Roig de Leuchsenring, Francisco González del Valle. Una copia del documento se encuentra en la Biblioteca Virtual “Miguel de Cervantes”, www.cervantesvirtual.co

Los últimos romanos. Tragedia en tres actos.

Obra de teatro adaptada por José María Heredia y Heredia cuyo texto base es un drama francés. El archivo es una copia del ejemplar resguardado en los fondos de la Biblioteca Nacional de Cuba "José Martí"

Evaluating the impact of existing legislation in Europe with regard to Female Genital Mutilation

The Spanish Report on the evaluation of existing legislation with regard to Female Genital Mutilation (FGM) is the result of a research project supported by the European Commision Daphne Programme. The project Evaluating the impact of existing legislation in Europe with regard to female genital mutilation, has been coordinated by the International Centre for Reproductive Health of Ghent University (Belgium) from january 2003 to march 2004. The project included as partners the Foundation for Women’s Health, Research and Development (FORWARD, United Kingdom); Lund University (Sweden); Commission pour l'Abolition des Mutilations Sexuelles, (CAMS, France), the Centre of Studies on Citizenship, Migration and Minorities of the University of Valencia (GECIM, Spain), and the above mentioned ICRH (Ghent University, Belgium) . The Spanish report is an interdisciplinary research done by the Centre of Studies on Citizenship, Migration and Minorities (University of València), directed by professor Javier De Lucas, and which counts with researchers and collaborators both, from the University of Valencia and other Universities such as University of Barcelona and University Rovira i Virgili of Tarragona; in the fields of Law (Penal Law, Constitutional Law, Theory and Philosophy of Law), Sociology and Antropology. The Group of researchers includes as well lawyers and public prosecutors. Practice of Female Genital Mutilation in Spain, like other european countries, address this rite that is introduced by immigrants from countries where the practice is prevalent (as we may see in chapter 3), as a violation of women’s rights and consider that such violation cannot be justified by respect of cultural traditions or initiation ceremonies. The increasing of immigration in Spain, has been a fact in last years, and it would be an important issue in future, increasing too the number of girls at risk in our country. In Spain, since october 2003, we have anew specific legislation, but before Female Genital Mutilation was liable too under the general offence of injuries in the Penal Code. In this Report, like in the other of the project, we have examined the possibilities and difficulties in the implementation of the spanish national legislation, in order to recommend a legislative and political strategy through Europe. page4image1440 The research methodology, common to all reports, was designed by the ICRH in its cooordination task, but was as well discussed by all the partners along the six steering commitee meetings we have had. The structure and content of report reflects the answers to following questions: 1. What is the legislation with regard to FGM in your country? Description of the legislation.; 2. What is the number of published court cases/suspected cases related to FGM in your country? What is the number of “hearsay” cases?; 3. Brief description of the practising community and the corresponding jurisdiction: number of Africans per country in the geographic area where the cases that you describe are located; 4. What is the procedure to be followed in case of a legal intervention to prevent or to penalise the performance of FGM?; 5. Is legislation applicable on FGM being implemented?; 6.What are the obstructing (favouring) factors for the implementation of legislation applicable to FGM? First of all we have compiled information about legislation applied with regard to FGM: not only general or specific criminal law, (in the case of Spain both because we have a change of law since october 2003), but also child protection procedures. In chapter 1, you may find the result: a Constitutional analysis, changes in Criminal Law, ans an introduction to Minor protection Laws. The second issue was the knowledge of court cases, police and judicial investigation in order to study how justice works. In this part, we contact key-informants, review archival records and study other reports: usually sociological, anthropological and health reports. In chapter 2 we have selected and summarized seven court cases in which we hace found enough relevant information to other parts of the report. At the same time, we need to identify the practicing communities to estimate the prevalence of women with FGM and the number of girls at risk of FGM. This was interesting not only to limit the research but to focus on a territory where there was a probability of cases in Court. We have choosen Catalonia: a community with court cases (in Barcelona and Girona) and prevalence of FGM; and Valencia, a territory without known cases and with no prevalence of FGM. This analysis is shown in chapter 3. In order to detect factors that hamper the implementation of existing legisaltion we need to know how procedures works at different levels: health services, social assistance, police, prosecution office and courts. Examining procedure laws, referral procedures, guidelines or ruled practices was not enough. We had to know what happen, who know a case, which institution examine it, which real mens they have.... To complete this, we have performe a study, interviewing key-informants with an standard interview: police, prosecutors, judges, doctors, nurses, social assistants and immigrants. Interviews were fulfilled in Valencia, Tarragona, Barcelona and Girona. Results are in Chapter 4 (procedure followed); Chapter 5 (implementation of appllicable legislation) and Chapter 6 (obstructing and favouring factors for the implementation of legislation). We had three main meetings to design the research and discuss texts and provissional results. Some of conclusions of provissional spanish report were discused in two seminars: “Ciudadania europea y conflictos culturales”, [european citizenship and cultural conflicts] (Valencia, 29, 30 and 31 october 2003); and “Violencia de género: instrumentos jurídicos en la lucha contra la discriminación de las mujeres”[Gender violence: legal instruments fighting agains women discrimination] (Valencia, 26, 27 and 28 november 2003) The study was financed by the European Commission, Daphne programme, and ran from January 2003 to March 2004 (EC-CONTRACT no 02/058/WYC). In additon, in the period we have done this study, the Centre of Studies on Citizenship, Migration and Minorities was financed with other projects related: “Indicadores y medidas para el desarrollo de políticas públicas de integración social de los inmigrantes y la garantía de sus derechos en la Comunidad Valenciana”, [indicators and measures to develop public policies for social integration of immigrants and the protection of their fundamental rights in the Land of Valencia], Project I+D “Generalitat Valenciana”; 2002-2003; "Los derechos fundamentales en las sociedades multiculturales" [fundamental rights in multicultural societies], project I+D, Subdirección General de Proyectos de Investigación, Dirección General de Investigación, Ministerio de Ciencia y Tecnología, november 2002-october 2005; “Los derechos de participación como elemento de integración de los inmigrantes” [participation rights as a element of the integration of immigrants], II Convocatoria de Ayudas a la Investigación en Economía, Demografía y Estudios de Población y Estudios Europeos de la Fundacion BBVA; 2004-2005. We wish to thank all who have collaborated in this study, specially we remark the collaboration and contributions of Elena Gascón Sorribas (Sociology of Law Laboratory; University of Zaragoza); María Heras García (Public Prosecutor); Dolores Gisbert Millet (Doctor, Health Service, Valencia); Ignacio de Lucas (Public Prosecutor); Laura Matilla (Lawyer, city council of Cullera); Joan Mayoral Simón (Justice Evaluating the impact of existing legislation with regard to Female Genital Mutilation..Spanish National Report. Daphne Programme Department, Regional Government of Catalonia); Xavier Montagud (Social Services, Regional Government of Valencia); and Dolores Sabater Collado (Court Secretary). With the results of the five National Report analysis and the information about legislation in all European Union member States, the coordinators, Els Leye and Jessika Deblonde, have elaborated A comparative analysis of the different legal approaches in the 15 EU Member States, and the respective judicial outcomes in Belgium, France, Spain, Sweden and the United Kingdom (ICRH, 2004)

Valoración inmunológica en la detección de la infección perioperatoria en pacientes intervenidos por cáncer de colon

Objective: evaluate the usefulness of quantification in the concentration of leukocytes and lymphocyte subpopulations in blood to identify the presence of anastomotic leak, in patients operated on for colon cancer, even before the appearance of clinical symptoms. Methods: Prospective observational study that consists of extracting different blood samples the day before surgery at 24 hours, 72 hours, and 120 hours post-surgery, to determine the lymphocyte subpopulations in patients that required a scheduled surgical intervention of colon cancer. Results: Sixty-two patients who underwent surgery for colon cancer were analysed for a period of 22 months, 7 of which presenting anastomotic leak. It was observed that presenting 379 cells/mm3 of LTCD4 at 72 hours after surgery indicated an anastomotic leak risk of 19.7 times more than those who had higher figures (p = 0.025). Conclusions: The monitoring of the lymphocyte subpopulations and more specifically of the LTCD4 during the perioperative period in colon cancer can serve to early detect the presence of anastomotic leak.Objetivos: Evaluar la utilidad de la cuantificación en la concentración de leucocitos y subpoblaciones linfocitarias en sangre para identificar la presencia de fuga anastomótica, en pacientes intervenidos de cáncer de colon, incluso antes de la aparición de síntomas clínicos. Método: Estudio prospectivo observacional que consiste en extraer diferentes muestras de sangre el día previo a la intervención, a las 24 horas, 72 horas y 120 horas post-cirugía, para determinar las subpoblaciones linfocitarias en pacientes que requirieron una intervención quirúrgica programada de cáncer de colon. Resultados: Se analizaron 62 enfermos intervenidos de cáncer de colon durante un periodo de 22 meses, de los cuales 7 pacientes presentaron fuga anastomótica, observándose que presentar ≤ 379 células/mm3 de LTCD4 a las 72 horas de la cirugía indicaba un riesgo de fuga anastomótica de 19,7 veces más respecto de aquellos que tienen cifras superiores (p=0,025). Conclusión: La monitorización de las subpoblaciones linfocitarias y más concretamente de los LTCD4 durante el periodo perioperatorio en el cáncer de colon puede servir para detectar de manera precoz la presencia de fuga anastomótica

Valoración inmunológica en la detección de la infección perioperatoria en pacientes intervenidos por cáncer de colon

Objetivos: Evaluar la utilidad de la cuantificación en la concentración de leucocitos y subpoblaciones linfocitarias en sangre para identificar la presencia de fuga anastomótica, en pacientes intervenidos de cáncer de colon, incluso antes de la aparición de síntomas clínicos. Método: Estudio prospectivo observacional que consiste en extraer diferentes muestras de sangre el día previo a la intervención, a las 24 horas, 72 horas y 120 horas post-cirugía, para determinar las subpoblaciones linfocitarias en pacientes que requirieron una intervención quirúrgica programada de cáncer de colon. Resultados: Se analizaron 62 enfermos intervenidos de cáncer de colon durante un periodo de 22 meses, de los cuales 7 pacientes presentaron fuga anastomótica, observándose que presentar ≤ 379 células/mm3 de LTCD4 a las 72 horas de la cirugía indicaba un riesgo de fuga anastomótica de 19,7 veces más respecto de aquellos que tienen cifras superiores (p=0,025). Conclusión: La monitorización de las subpoblaciones linfocitarias y más concretamente de los LTCD4 durante el periodo perioperatorio en el cáncer de colon puede servir para detectar de manera precoz la presencia de fuga anastomótica

The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients

We aimed to evaluate the prognostic and predictive value of the nucleotide excision repair-related gene GTF2H5, which is localized at the 6q24.2-26 deletion previously reported by our group to predict longer survival of high-grade serous ovarian cancer patients. In order to test if protein levels of GTF2H5 are associated with patients' outcome, we performed GTF2H5 immunohistochemical staining in 139 high-grade serous ovarian carcinomas included in tissue microarrays. Upon stratification of cases into high- and low-GTF2H5 staining categories (> and ≤ median staining, respectively) Kaplan-Meier and log-rank test were used to estimate patients' survival and assess statistical differences. We also evaluated the association of GTF2H5 with survival at the transcriptional level by using the on-line Kaplan-Meier plotter tool, which includes gene expression and survival data of 855 high-grade serous ovarian cancer patients from 13 different datasets. Finally, we determined whether stable short hairpin RNA-mediated GTF2H5 downregulation modulates cisplatin sensitivity in the SKOV3 and COV504 cell lines by using cytotoxicity assays. Low expression of GTF2H5 was associated with longer 5-year survival of patients at the protein (hazard ratio [HR], 0.52; 95% CI, 0.29 to 0.93; p=0.024) and transcriptional level (HR, 0.80; 95% CI, 0.65 to 0.97; p=0.023) in high-grade serous ovarian cancer patients. We confirmed the association with 5-year overall survival (HR, 0.55; 95% CI, 0.38 to 0.78; p=0.0007) and also found an association with progression-free survival (HR, 0.72; 95% CI, 0.54 to 0.96; p=0.026) in a homogenous group of 388 high-stage (stages III-IV using the International Federation of Gynecology and Obstetrics staging system), optimally debulked high-grade serous ovarian cancer patients. GTF2H5- silencing induced a decrease of the half maximal inhibitory concentration upon cisplatin treatment in GTF2H5 -silenced ovarian cancer cells. Low levels of GTF2H5 are associated with enhanced prognosis in high-grade serous ovarian cancer patients and may contribute to cisplatin sensitization

Perfil avanzado. Proyecto de fortalecimiento del SENASA

El presente proyecto forma parte de la primera etapa del proceso de modernización institucional del SENASA con una visión estratégica de mediano y largo plazo. La ejecución del proyecto en esta primera etapa incluye tres tipos de acciones. El proyecto contribuirá a superar una parte de las limitantes existentes y sentará las bases para solucionar a futuro otras limitantes que requieren un proceso más largo de diseño y ejecución. La carta de navegación con visión de largo plazo (10 años), está dirigida a sentar las bases para que el SENASA se constituya a futuro en un organismo rector, normativo y fiscalizador de los servicios de salud animal e inocuidad de alimentos

Aspectos fiscales y económicos del federalismo argentino

Fil: Hernández, Antonio M. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Frías, Pedro J.. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Dalla Vía, Alberto. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Barrera Buteler, Guillermo. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Heredia, José Raúl. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Asensio, Miguel Ángel. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Bertaina, Norberto. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Rezk, Ernesto. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Midón, Mario A. R. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Martínez, Luis Alberto. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Palazzo, Eugenio Luis. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Prieto, Hugo N. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Frediani, Ramón. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Roccatagliata, Juan A. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Fil: Della Paolera, Claude F. Academia Nacional de Derecho y Ciencias Sociales de Córdoba; Argentina.Con este libro se inicia una serie de publicaciones que integrarán la “Colección sobre Federalismo Argentino”, destinada al análisis de sus distintos aspectos. El objetivo no es otro que avanzar en el conocimiento, difusión, debate y estudio de nuestro federalismo, que es uno de los principios fundamentales de nuestra organización política y constitucional.Introducción / Antonio M. Hernández – Los aspectos financieros y económicos del federalismo argentino / Antonio M. Hernández – Unitarismo fiscal / Pedro J. Frías – El sistema federal fiscal / Alberto Dalla Vía – La distribución de la renta tributaria federal y el sistema de coparticipación en la organización constitucional argentina / Pablo María Garat – La ruptura del pacto federal en lo fiscal / Guillermo Barrera Buteler – Aspectos fiscales del federalismo, con especial referencia al poder tributario municipal / José Raúl Heredia – Nueva mirada a las finanzas federativas argentinas del siglo XXI / Miguel Angel Asensio – Federalismo fiscal, su deterioro / Norberto Bertaina – Nueva propuesta de arreglos fiscales interjurisdiccionales para Argentina / Ernesto Rezk – Convenios internacionales y tratados de regionalización / Mario A. R. Midón – Economía y orden jurídico / Luis Alberto Martínez – El Banco Federal / Eugenio Luis Palazzo – El dominio de los recursos naturales. La titularidad de las provincias y sus consecuencias en materia de hidrocarburos / Hugo N. Prieto – Federalización del Banco Central de la República Argentina / Ramón Frediani – Federalismo y política territorial en los inicios del tercer milenio / Juan A. Roccatagliata – Argentina invertebrada. La ausencia de una política nacional de ordenamiento territorial / Claude F. della Paolera