4,569 research outputs found
Varieties of digital authoritarianism analyzing Russia’s approach to internet governance
Digital authoritarianism threatens the privacy and rights of Internet users worldwide, yet scholarship on this topic remains limited in analytical power and case selection. In this article, we introduce a comprehensive analytical framework to the field of Internet governance and apply it first, briefly, to the well-known case of China and then, in more depth, to the still-understudied Russian case. We identify the extent and relative centralization of Internet governance as well as proactive versus reactive approaches to governance as notable differences between the cases, highlighting variation among digital authoritarians’ governance strategies. We conclude that Russia’s Internet governance model is less comprehensive and consistent than China’s, but its components may be more easily exported to other political systems. We then consider whether recent changes to Russia’s Internet governance suggest that it could converge with the Chinese model over time
Complaint-making as political participation in contemporary Russia
Prior to December 2011, instances of widespread collective mobilization were relatively rare in contemporary Russia. Russian citizens are more likely to engage in a different means of airing grievances: making an official complaint to the authorities. This article considers how complaint-making, as a variety of political participation, may contribute either to authoritarian resilience or to political liberalization. The political significance of complaints made to the Commissioner for Human Rights of the Russian Federation is examined. Since it is the broader political context that shapes the significance of complaints, in the absence of meaningful elections individualized appeals to the state are unlikely to promote democratic change, although they may allow for redress of individual rights violations. © 2012 The Regents of the University of California
Climate Policy Constraints: Yet Another Negative Reverberation of Russia's War in Ukraine?
Prior to Russia's invasion of Ukraine in February 2022, the Russian government was taking modest but meaningful steps to develop its domestic climate policy, prompted in part by incentives and pressures from the international market. Since then, however, Russia's war in Ukraine has heightened obstacles to addressing climate change: it has reinforced the importance of fossil fuel exports, further stifled climate activism at home, and increased impediments to international cooperation. The war’s longer-term impact on decarbonization remains uncertain
Environmental issues in russia
This review examines the literature available on the state of the environment and environmental protection in the Russian Federation. As the largest country on Earth, rich in natural resources and biodiversity, Russia\u27s problems and policies have global consequences. Environmental quality and management are influenced by the legacy of Soviet economic planning and authoritarian governance, as well as by Russia\u27s post-Soviet economic recession and current strategies of economic development. Russia achieved a reduction in some pollutants owing to the collapse of industrial production in the 1990s, but many environmental indicators suggest growing degradation. Russia has signed on to a number of international environmental agreements, but its record on implementation is mixed, and it discourages environmental activism. Scholarship on the Russian environment is a limited, but growing, field, constrained by challenges of data availability, yet it offers great potential for testing scientific and social scientific hypotheses. ©2008 by Annual Reviews
Environmental issues in Russia
This review examines the literature available on the state of the environment and environmental protection in the Russian Federation. As the largest country on Earth, rich in natural resources and biodiversity, Russia\u27s problems and policies have global consequences. Environmental quality and management are influenced by the legacy of Soviet economic planning and authoritarian governance, as well as by Russia\u27s post-Soviet economic recession and current strategies of economic development. Russia achieved a reduction in some pollutants owing to the collapse of industrial production in the 1990s, but many environmental indicators suggest growing degradation. Russia has signed on to a number of international environmental agreements, but its record on implementation is mixed, and it discourages environmental activism. Scholarship on the Russian environment is a limited, but growing, field, constrained by challenges of data availability, yet it offers great potential for testing scientific and social scientific hypotheses. ©2008 by Annual Reviews
The Effect of Transient HMG-CoA Reductase and 1-Deoxy-D-Xylulose-5-Phosphate Synthase Overexpression on Terpene Production in Transgenic Tomato Fruits
Isoprenoids are secondary metabolites that control numerous plant functions including signaling, growth, photosynthesis, and membrane structure. The bioengineering of isoprenoid synthesis could produce plants with a variety of beneficial traits. Plants form isoprenoids using two different pathways, the mevalonate (MVA) pathway and the methylerithritol phosphate (MEP) pathway, which cooperate via metabolic cross-talk. Transgenic tomato lines expressing both the plastidic and cytosolic forms of the snapdragon nerolidol/linalool terpene synthase under a fruit ripening specific promoter were transiently transformed to overexpress key enzymes in the two isoprenoid pathways. Hydroxymethylglutaryl-coenzyme A reductase (HMGR) is the rate limiting enzyme in the MVA pathway that was selected for overexpression. 1-deoxy-D-xylulose-5-phosphate synthase (DXPS) in the plastid was targeted as it is the first committed step in the MEP pathway. HMGR and DXPS coding regions were cloned into binary vectors under a constitutive promoter and introduced into Agrobacterium tumefaciens which were then injected into ripening tomato fruits for transient expression. Additionally, untransformed fruits were incubated with either the MVA-inhibitor mevinolin or the MEP-inhibitor fosmidomycin. Terpene production was characterized by gas chromatography and mass spectrometery of fruit volatiles collected at the ripe stage. Inhibitor treatment is expected to decrease terpene synthesis in the same compartment as the inhibited pathway. The overexpression of early MVA and MEP pathway genes is expected to significantly increase the formation of terpenes
Inferences on the Timeline of Reionization at z~8 From the KMOS Lens-Amplified Spectroscopic Survey
Detections and non-detections of Lyman alpha (Ly) emission from
galaxies ( Gyr after the Big Bang) can be used to measure the timeline of
cosmic reionization. Of key interest to measuring reionization's mid-stages,
but also increasing observational challenge, are observations at z > 7, where
Ly redshifts to near infra-red wavelengths. Here we present a search
for z > 7.2 Ly emission in 53 intrinsically faint Lyman Break Galaxy
candidates, gravitationally lensed by massive galaxy clusters, in the KMOS
Lens-Amplified Spectroscopic Survey (KLASS). With integration times of ~7-10
hours, we detect no Ly emission with S/N>5 in our sample. We determine
our observations to be 80% complete for 5 spatially and spectrally
unresolved emission lines with integrated line flux erg
s cm. We define a photometrically selected sub-sample of 29
targets at , with a median 5 Ly EW limit of 58A.
We perform a Bayesian inference of the average intergalactic medium (IGM)
neutral hydrogen fraction using their spectra. Our inference accounts for the
wavelength sensitivity and incomplete redshift coverage of our observations,
and the photometric redshift probability distribution of each target. These
observations, combined with samples from the literature, enable us to place a
lower limit on the average IGM neutral hydrogen fraction of at z ~ 8, providing further evidence of rapid reionization
at z~6-8. We show that this is consistent with reionization history models
extending the galaxy luminosity function to , with
low ionizing photon escape fractions, .Comment: Accepted for publication in MNRA
Endothelial dysfunction and carotid atherosclerosis in Malawian adults: A cross-sectional study
Background and objective
In sub-Saharan Africa, data on prevalence, risk factors and pathobiology of carotid atherosclerosis are scarce. We aimed to investigate the relationship between biomarkers of endothelial dysfunction and carotid atherosclerosis.
Methods
Carotid ultrasound was performed in 66 patients. Plasma concentration of ICAM-1, PAI-1, VEGF, and soluble thrombomodulin were measured by ELISA. A univariable logistic regression analysis was performed to study the relationship between carotid atherosclerosis, biomarkers of endothelial dysfunction, and various demographic and clinical parameters of the participants.
Results
The mean age of the participants was 58.7 years (95% CI: 54.4–63.1). Carotid atherosclerosis was diagnosed in 39.4% (95% CI: 27.6–52.2). In the univariable logistic regression, the following factors were associated with carotid atherosclerosis: age > 45 years (OR = 12.0, 95% CI: 1.4–98.8, p = .02), hypertension (OR = 3.8, 95% CI: 1.2–12.1, p = .02), and high-level of soluble thrombomodulin (OR = 3.4, 95% CI: 1.2–10.0, p = .02).
Conclusions
There is an association between high levels of soluble thrombomodulin and carotid atherosclerosis in Malawian adults. Further studies with a larger sample size are needed to confirm our findings in other African populations
Climate change and the kidney
The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality. The kidney has a unique role not only in protecting the host from heat and dehydration but also is an important site of heat-associated disease. Here we review the potential impact of global warming and heat extremes on kidney diseases. High temperatures can result in increased core temperatures, dehydration, and blood hyperosmolality. Heatstroke (both clinical and subclinical whole-body hyperthermia) may have a major role in causing both acute kidney disease, leading to increased risk of acute kidney injury from rhabdomyolysis, or heat-induced inflammatory injury to the kidney. Recurrent heat and dehydration can result in chronic kidney disease (CKD) in animals and theoretically plays a role in epidemics of CKD developing in hot regions of the world where workers are exposed to extreme heat. Heat stress and dehydration also has a role in kidney stone formation, and poor hydration habits may increase the risk for recurrent urinary tract infections. The resultant social and economic consequences include disability and loss of productivity and employment. Given the rise in world temperatures, there is a major need to better understand how heat stress can induce kidney disease, how best to provide adequate hydration, and ways to reduce the negative effects of chronic heat exposure.Published versio
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