The Head, the Heart and the Hand: Co-Creating and Personalising a Client Service Charter and Culture at the University of Western Australia

UWA’s strategic plan to enhance the student experience underpinned funding for the refurbishment of several UWA libraries in 2016/2017. The benefits of these projects were quickly realised with library visits increasing by 30% in two years. An imperative emerged: how to align a large group of frontline staff with diverse experience and skills to a shared vision, reflective of the university’s strategic priority, and use this as a basis to evolve library services in line with changing client volume and expectations, without additional staffing? In 2018 UWA Library commenced a project to create a client service charter for all frontline staff, with aim of articulating a unique, high quality and holistic standard for client service in the UWA context. All frontline staff as well as UWA students and stakeholders were invited to participate in the co-creation of the service charter. The crafting process utilised user-centred design strategies and strategic environmental scanning. Embedding the charter more deeply into the culture, as well as the interpersonal and technical practices for frontline staff involved a range of creative techniques, including peer dialogue, personalising and serious play. For the leadership team, new competencies were needed to enable a more modern client service culture to emerge. Research in the disciplines of customer service and emotional labour provided new insights into the client, employee and management perspectives, and empowered a more confident and proactive service culture. The UWA case study presented in this paper will illustrate the necessary interconnected elements of client service transformation in the academic library context. The paper will also demonstrate the sustained performance improvements at UWA as a result of action on all three elements, the head, the heart and the hand. Finally, it will offer a framework for improving student experience via the co-creation and personalisation of a charter and service culture

CYP2 family: physiological enzymes subset in GtoPdb v.2021.2

Compared to the other CYP2 family enzymes, this subset have physiological rather than drug metabolising enzyme activities

Cytochrome P450 in GtoPdb v.2021.2

The cytochrome P450 enzyme superfamily (CYP), E.C. 1.14.-.-, are haem-containing monooxygenases with a vast range of both endogenous and exogenous substrates. These include sterols, fatty acids, eicosanoids, fat-soluble vitamins, hormones, pesticides and carcinogens as well as drugs. Listed below are the human enzymes, their relationship with rodent CYP enzyme activities is obscure in that the species orthologue may not metabolise the same substrates. Some of the CYP enzymes located in the liver are particularly important for drug metabolism, both hepatic and extrahepatic CYP enzymes also contribute to patho/physiological processes. Genetic variation of CYP isoforms is widespread and likely underlies a proportion of individual variation in drug disposition. The superfamily has the root symbol CYP, followed by a number to indicate the family, a capital letter for the subfamily with a numeral for the individual enzyme. Some CYP are able to metabolise multiple substrates, others are oligo- or mono- specific

Cytochrome P450 (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

The cytochrome P450 enzyme family (CYP450), E.C. 1.14.-.-, were originally defined by their strong absorbance at 450 nm due to the reduced carbon monoxide-complexed haem component of the cytochromes. They are an extensive family of haem-containing monooxygenases with a huge range of both endogenous and exogenous substrates. These include sterols, fat-soluble vitamins, pesticides and carcinogens as well as drugs. The substrates of some orphan CYP are not known. Listed below are the human enzymes; their relationship with rodent CYP450 enzyme activities is obscure in that the species orthologue may not catalyse the metabolism of the same substrates. Although the majority of CYP450 enzyme activities are concentrated in the liver, the extrahepatic enzyme activities also contribute to patho/physiological processes. Genetic variation of CYP450 isoforms is widespread and likely underlies a significant proportion of the individual variation to drug administration

Cytochrome P450 in GtoPdb v.2023.1

The cytochrome P450 enzyme superfamily (CYP), E.C. 1.14.-.-, are haem-containing monooxygenases with a vast range of both endogenous and exogenous substrates. These include sterols, fatty acids, eicosanoids, fat-soluble vitamins, hormones, pesticides and carcinogens as well as drugs. Listed below are the human enzymes, their relationship with rodent CYP enzyme activities is obscure in that the species orthologue may not metabolise the same substrates. Some of the CYP enzymes located in the liver are particularly important for drug metabolism, both hepatic and extrahepatic CYP enzymes also contribute to patho/physiological processes. Genetic variation of CYP isoforms is widespread and likely underlies a proportion of individual variation in drug disposition. The superfamily has the root symbol CYP, followed by a number to indicate the family, a capital letter for the subfamily with a numeral for the individual enzyme. Some CYP are able to metabolise multiple substrates, others are oligo- or mono- specific. CYP also catalyse diverse oxidation and reduction reactions. These include ring hydroxylation, N-oxidation, sulfoxidation, epoxidation, the dealkylation of N-, S- and O- moieties, desulfation, deamination, as well as reduction of azo, nitro and N-oxide groups

Cytochrome P450 (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

The cytochrome P450 enzyme family (CYP450), E.C. 1.14.-.-, were originally defined by their strong absorbance at 450 nm due to the reduced carbon monoxide-complexed haem component of the cytochromes. They are an extensive family of haem-containing monooxygenases with a huge range of both endogenous and exogenous substrates. These include sterols, fat-soluble vitamins, pesticides and carcinogens as well as drugs. The substrates of some orphan CYP are not known. Listed below are the human enzymes; their relationship with rodent CYP450 enzyme activities is obscure in that the species orthologue may not catalyse the metabolism of the same substrates. Although the majority of CYP450 enzyme activities are concentrated in the liver, the extrahepatic enzyme activities also contribute to patho/physiological processes. Genetic variation of CYP450 isoforms is widespread and likely underlies a significant proportion of the individual variation to drug administration

6. The 1960s

From David Moore – “I served as dean of the ILR School during the 1960s. This was a period that started in relative tranquility and ended in tumultuous disarray with students demonstrating, administrators trying to maintain control, and faculty worrying about traditional academic freedom and values.” Includes: Remembrances of Things Past – 1963-71; Creation of the Public Employment Relations Board; and Alumni Perspectives

7. The 1970s

From View from the Dean’s Office by Robert McKersie. “I had been on the job just a week when Keith Kennedy, vice provost, called and said we needed to make a trip to Albany to meet the chancellor of SUNY, Ernest Boyer. This was late August 1971. After a few pleasantries, it became clear that this was not just the courtesy call of a new dean reporting in to the top leader of the state university. Chancellor Boyer went right to the point: a new Labor College was going to open on the premises of Local 3 IBEW’s training facility on Lexington Avenue in Manhattan, and the ILR School had to be there as a partner. It was not clear what unit of SUNY would take over the Labor College, but it was clear that given its broad mandate for labor education, the ILR School was going to play a key role.” Includes: View from the Dean’s Office; From Eric Himself; Another Perspective; Labor College Graduation: VanArsdale’s Dream Fulfilled; The View of a Visiting Faculty Member; Another Perspective; and The Student’s View

GEANT4 Simulation of a Cosmic Ray Muon Tomography System with Micro-Pattern Gas Detectors for the Detection of High-Z Materials

Muon Tomography (MT) based on the measurement of multiple scattering of atmospheric cosmic ray muons traversing shipping containers is a promising candidate for identifying threatening high-Z materials. Since position-sensitive detectors with high spatial resolution should be particularly suited for tracking muons in an MT application, we propose to use compact micro-pattern gas detectors, such as Gas Electron Multipliers (GEMs), for muon tomography. We present a detailed GEANT4 simulation of a GEM-based MT station for various scenarios of threat material detection. Cosmic ray muon tracks crossing the material are reconstructed with a Point-Of-Closest-Approach algorithm to form 3D tomographic images of the target material. We investigate acceptance, Z-discrimination capability, effects of placement of high-Z material and shielding materials inside the cargo, and detector resolution effects for such a MT station.Comment: 9 pages, 10 figures, submitted to conference proceedings of SORMA West 08, Berkele