La cultura organizacional y su relación con el engagement laboral en los gerentes de agencias bancarias, Lima, 2021

La presente investigación tiene como objetivo determinar la relación entre la Cultura Organizacional y el Engagement laboral en los gerentes de agencias bancarias en la ciudad de Lima en el año 2021. El método de investigación utilizado tiene un enfoque cuantitativo, de diseño no experimental, de alcance descriptivo correlacional y de corte transversal. La técnica es la encuesta y el instrumento de recolección de datos es un cuestionario de propia autoría formulado con 18 preguntas y con opciones de respuesta en la escala Likert. El instrumento de investigación está validado por 3 docentes investigadores expertos, con una confiabilidad de Alfa de Cronbach de 0,891. La muestra es no probabilística por conveniencia compuesta por 150 gerentes de agencias bancarias ubicadas en la ciudad Lima. Los datos obtenidos se procesaron con el programa estadístico SPSS 25 donde se obtuvieron cifras que determinan la existencia de relación positiva entre la Cultura organizacional y el Engagement laboral en los gerentes de agencias bancarias, Lima, 2021. Se concluye que existe una correlación positiva moderada (Rho de Spearman = 0.523) entre la cultura organizacional y el Engagement laboral.The objective of this research is to determine the relationship between Organizational Culture and Work Engagement in managers of banking agencies in the city of Lima in 2021. The research method used has a quantitative approach, non-experimental design, of scope descriptive correlational and cross-sectional. The technique is the survey and the data collection instrument is a self-authored questionnaire formulated with 18 questions and with response options on the Likert scale. The research instrument is validated by 3 expert research teachers, with a Cronbach's Alpha reliability of 0.891. The sample is non-probabilistic for convenience, composed of 150 managers of banking agencies located in the city of Lima. The data obtained were processed with the statistical program SPSS 25 where figures were obtained that determine the existence of a positive relationship between Organizational Culture and Work Engagement in managers of banking agencies, Lima, 2021. It is concluded that there is a moderate positive correlation (Spearman's Rho = 0.523) between organizational culture and work engagement. Keyword

Evolución de la cultura organizacional en las empresas de Latinoamérica: una revisión sistemática de la literatura científica en los últimos 5 años, 2015-2020

Nuestra indagación desarrolla una comparación de distintas estrategias para comprender la Cultura Organizacional en los países latinoamericanas entre los años 2015 al 2020. En tal sentido se utilizaron fuentes confiables como: EBSCOhost, ProQuest, Scielo y Redalyc. Los métodos de inserción fueron artículos científicos que contestaron nuestra investigación sobre la importancia y estrategias desarrolladas en las empresas latinoamericanas sobre cultura organizacional donde rescatamos un total de 61 revista científicas, 20 de ellas respondieron a nuestra investigación Colombia siendo el país con mayor cantidad de aporte, dichas empresas se han ocupado con mayor énfasis a la estrategia, importancia, innovación y satisfacción dentro de la Cultura Organizacional. Las restricciones fueron la falta previa de la indagación sobre las preguntas y los obstáculos como estudiantes en el uso de procedimientos metodológicos. El resultado de sus investigaciones va dirigidos a un patrón de escasos sustentos que aporten a la investigación. En conclusión, está investigación señala la importancia de la cultura organizacional y sus estrategias que se emplean en las empresas, donde cumplen una aceptación positiva e involucran a los subordinados para llegar al objetivo deseado.Our investigation develops a comparison of different strategies to understand Organizational Culture in Latin American countries between 2015 and 2020. In this sense, reliable sources such as: EBSCOhost, ProQuest, Scielo and Redalyc will be used. The insertion methods were scientific articles that answered our research on the importance and strategies developed in Latin American companies on organizational culture where a total of 61 scientific journals are rescued, 20 of them responded to our research, Colombia being the country with the largest number of reports These businesses have been occupied with the greatest emphasis on strategy, importance, innovation and satisfaction within the Organizational Culture. The restrictions were the previous lack of information on the questions and the obstacles as students in the use of methodological procedures. The result of their investigations is directed to a pattern of few livelihoods that contribute to the investigation. In conclusion, he is investigating the importance of organizational culture and its strategies that are used in companies, where positive acceptance is accepted and subordinates are involved in reaching the desired objective

Energy transmission in Hamiltonian systems of globally interacting particles with Klein-Gordon on-site potentials

We consider a family of 1-dimensional Hamiltonian systems consisting of a large number of particles with on-site potentials and global (long range) interactions. The particles are initially at rest at the equilibrium position, and are perturbed sinusoidally at one end using Dirichlet data, while at the other end we place an absorbing boundary to simulate a semi-infinite medium. Using such a lattice with quadratic particle interactions and Klein-Gordon type on-site potential, we use a parameter 0 ≤ α < ∞as a measure of the “length” of interactions, and show that there is a sharp threshold above which energy is transmitted in the form of large amplitude nonlinear modes, as long as driving frequencies Ω lie in the forbidden band-gap of the system. This process is called nonlinear supratransmission and is investigated here numerically to show that it occurs at higher amplitudes the longer the range of interactions, reaching a maximum at a value α = αmax . 1.5 that depends on Ω. Below this αmax supratransmission thresholds decrease sharply to values lower than the nearest neighbor α = ∞ limit. We give a plausible argument for this phenomenon and conjecture that similar results are present in related systems such as the sine-Gordon, the nonlinear Klein-Gordon and the double sine-Gordon type

Planning an integrated disease surveillance and response system: a matrix of skills and activities

<p>Abstract</p> <p>Background</p> <p>The threat of a global influenza pandemic and the adoption of the World Health Organization (WHO) International Health Regulations (2005) highlight the value of well-coordinated, functional disease surveillance systems. The resulting demand for timely information challenges public health leaders to design, develop and implement efficient, flexible and comprehensive systems that integrate staff, resources, and information systems to conduct infectious disease surveillance and response. To understand what resources an integrated disease surveillance and response system would require, we analyzed surveillance requirements for 19 priority infectious diseases targeted for an integrated disease surveillance and response strategy in the WHO African region.</p> <p>Methods</p> <p>We conducted a systematic task analysis to identify and standardize surveillance objectives, surveillance case definitions, action thresholds, and recommendations for 19 priority infectious diseases. We grouped the findings according to surveillance and response functions and related them to community, health facility, district, national and international levels.</p> <p>Results</p> <p>The outcome of our analysis is a matrix of generic skills and activities essential for an integrated system. We documented how planners used the matrix to assist in finding gaps in current systems, prioritizing plans of action, clarifying indicators for monitoring progress, and developing instructional goals for applied epidemiology and in-service training programs.</p> <p>Conclusion</p> <p>The matrix for Integrated Disease Surveillance and Response (IDSR) in the African region made clear the linkage between public health surveillance functions and participation across all levels of national health systems. The matrix framework is adaptable to requirements for new programs and strategies. This framework makes explicit the essential tasks and activities that are required for strengthening or expanding existing surveillance systems that will be able to adapt to current and emerging public health threats.</p

Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma: The PROACT Clinical Trial

BackgroundCardiotoxicity is a concern for cancer survivors undergoing anthracycline chemotherapy. Enalapril has been explored for its potential to mitigate cardiotoxicity in cancer patients. The dose-dependent cardiotoxicity effects of anthracyclines can be detected early through the biomarker cardiac troponin.ObjectivesThe PROACT (Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma) clinical trial assessed the effectiveness of enalapril in preventing cardiotoxicity, manifesting as myocardial injury and cardiac function impairment, in patients undergoing high-dose anthracycline-based chemotherapy for breast cancer or non-Hodgkin lymphoma.MethodsThis prospective, multicenter, open-label, randomized controlled trial employed a superiority design with observer-blinded endpoints. A total of 111 participants, scheduled for 6 cycles of chemotherapy with a planned dose of ≥300 mg/m2 doxorubicin equivalents, were randomized to receive either enalapril (titrated up to 20 mg daily) or standard care without enalapril.ResultsMyocardial injury, indicated by cardiac troponin T (≥14 ng/L), during and 1 month after chemotherapy, was observed in 42 (77.8%) of 54 patients in the enalapril group vs 45 (83.3%) of 54 patients in the standard care group (OR: 0.65; 95% CI: 0.23-1.78). Injury detected by cardiac troponin I (&gt;26.2 ng/L) occurred in 25 (47.2%) of 53 patients on enalapril compared with 24 (45.3%) of 53 in standard care (OR: 1.10; 95% CI: 0.50-2.38). A relative decline of more than 15% from baseline in left ventricular global longitudinal strain was observed in 10 (21.3%) of 47 patients on enalapril and 9 (21.9%) of 41 in standard care (OR: 0.95; 95% CI: 0.33-2.74). An absolute decline of &gt;10% to &lt;50% in left ventricular ejection fraction was seen in 2 (4.1%) of 49 patients on enalapril vs none in patients in standard care.ConclusionsAdding enalapril to standard care during chemotherapy did not prevent cardiotoxicity in patients receiving high-dose anthracycline-based chemotherapy. (PROACT: Can we prevent Chemotherapy-related Heart Damage in Patients With Breast Cancer and Lymphoma?; NCT03265574

Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK

In March 2020, the United Kingdom Primary Immunodeficiency Network (UKPIN) established a registry of cases to collate the outcomes of individuals with PID and SID following SARS-CoV-2 infection and treatment. A total of 310 cases of SARS-CoV-2 infection in individuals with PID or SID have now been reported in the UK. The overall mortality within the cohort was 17.7% (n = 55/310). Individuals with CVID demonstrated an infection fatality rate (IFR) of 18.3% (n = 17/93), individuals with PID receiving IgRT had an IFR of 16.3% (n = 26/159) and individuals with SID, an IFR of 27.2% (n = 25/92). Individuals with PID and SID had higher inpatient mortality and died at a younger age than the general population. Increasing age, low pre-SARS-CoV-2 infection lymphocyte count and the presence of common co-morbidities increased the risk of mortality in PID. Access to specific COVID-19 treatments in this cohort was limited: only 22.9% (n = 33/144) of patients admitted to the hospital received dexamethasone, remdesivir, an anti-SARS-CoV-2 antibody-based therapeutic (e.g. REGN-COV2 or convalescent plasma) or tocilizumab as a monotherapy or in combination. Dexamethasone, remdesivir, and anti-SARS-CoV-2 antibody-based therapeutics appeared efficacious in PID and SID. Compared to the general population, individuals with PID or SID are at high risk of mortality following SARS-CoV-2 infection. Increasing age, low baseline lymphocyte count, and the presence of co-morbidities are additional risk factors for poor outcome in this cohort

Processed pseudogenes acquired somatically during cancer development

Cancer evolves by mutation, with somatic reactivation of retrotransposons being one such mutational process. Germline retrotransposition can cause processed pseudogenes, but whether this occurs somatically has not been evaluated. Here we screen sequencing data from 660 cancer samples for somatically acquired pseudogenes. We find 42 events in 17 samples, especially non-small cell lung cancer (5/27) and colorectal cancer (2/11). Genomic features mirror those of germline LINE element retrotranspositions, with frequent target-site duplications (67%), consensus TTTTAA sites at insertion points, inverted rearrangements (21%), 5′ truncation (74%) and polyA tails (88%). Transcriptional consequences include expression of pseudogenes from UTRs or introns of target genes. In addition, a somatic pseudogene that integrated into the promoter and first exon of the tumour suppressor gene, MGA, abrogated expression from that allele. Thus, formation of processed pseudogenes represents a new class of mutation occurring during cancer development, with potentially diverse functional consequences depending on genomic context

Approaches in biotechnological applications of natural polymers

Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento Cientfíico e Tecnológico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de Nvíel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)

Are identities oral? Understanding ethnobotanical knowledge after Irish independence (1937-1939)

BACKGROUND: The Schools' Folklore Scheme (1937-1939) was implemented at a pivotal time in Irelands' political history. It resulted in a body of ethnological information that is unique in terms of when, why and how it was collected. This material consists of over 700,000 pages of information, including ethnomedicinal and ethnobotanical traditions, reflecting an oral identity that spans generations and that in many cases was not documented in writing until the 1930s. The intention of this study is to highlight the importance of the Schools' Folklore Scheme and to demonstrate an ethnographic approach based on recollections of original participants of the scheme, to further understand the material in the collection and the impact it had on the participants. METHODS: This study involves an analysis of both oral and archival data. Eleven semi-structured interviews with original participants of the scheme were carried out between April and September 2016. Their corresponding schools' archival contributions to the scheme were located, and ethnomedicinal information was analysed and compared with the participants' recollections. RESULTS: The majority of participants' stated the scheme had a positive impact on them. Five participants' recalled collecting ethnomedicinal information, and there was a direct correlation between three of the participants' ethnomedicinal recollections and their entries in the archives. One third of all the ethnomedicinal entries analysed included the use of a plant. There were 191 plant mentions and 64 plant species named. CONCLUSIONS: Contacting the original participants offers a novel approach of analysing this archival material. It provides a unique first-hand account of this historical initiative, an insight into how the scheme was implemented and how it impacted upon the children. The ethnomedicinal and ethnobotanical information provides an understanding of the medicinal practices in Ireland during the 1930s. The plant species that were both orally recalled by participants and documented in the archives are in keeping with key ethnomedicinal systems throughout the world