23 research outputs found
Why medical students choose not to carry out an intercalated BSc : a questionnaire study.
Peer reviewedPublisher PD
Sensory Mapping of Lumbar Facet Joint Pain : A feasibility study
Acknowledgements The authors would like to thank Dr Jeremy Weinbren, Consultant Anaesthetist, The Hillingdon Hospitals NHS Foundation Trust for his statistical advice on this paper. Funding The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: K.F. received a John Snow Anaesthesia Intercalated BSc bursary. No funding was obtained for the running costs of the project.Peer reviewedPostprin
Melatonin as a potential therapy for sepsis : a phase I dose escalation study and an ex vivo whole blood model under conditions of sepsis
This article is protected by copyright. All rights reserved. This study was funded by the Chief Scientist Office, NHS Scotland. We would like to thank all the volunteers who gave up their time and blood to take part in the study and the data monitoring committee and staff of the intensive care unit for their support. In addition, thanks to Dr Malachy Columb for performing Page's trend test for us and to Annette Fearnley at Nu-Pharm Ltd for her advice.Peer reviewedPublisher PD
Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis
Funding: This research was funded by The British Journal of Anaesthesia/Royal College of Anaesthetists (PhD studentship to Beverley Minter). Acknowledgments: We are very grateful to Professor M.P. Murphy, MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge, UK for the generous gift of MitoVitE used in all the experiments, without which this work would not have been possible.Peer reviewedPublisher PD
Maternal serum melatonin increases during pregnancy and falls immediately after delivery implicating the placenta as a major source of melatonin
FUNDING The work was funded by non-specific institutional sources. ACKNOWLEDGMENTS We wish to thank Emil Peshtenski for technical support and all the pregnant ladies who generously participated in this work.Peer reviewedPublisher PD
Melatonin is a feasible, safe and acceptable intervention in doctors and nurses working nightshifts : the MIDNIGHT trial
Funding: The study was funded by the British Journal of Anaesthesia and the Royal College of Anaesthetists, funding partners of the National Institute of Academic Anaesthesia (grant number WKR0-2015-0027). Acknowledgments: We are extremely grateful to Flynn Pharma for the gift of Circadin and placebo tablets for this trial, to Gary Cameron for the assay of melatonin, and to Sally Galt for helping with recruitment. We also thank Drs Lorna Aucott and David McClernon of the medical statistics team for help with randomization. We acknowledge the members of the Trial Steering Group and the Data and Safety Monitoring Committee. Finally we thank all the doctors and nurses who took part in this trial.Peer reviewedPublisher PD
Bench-to-bedside review : targeting antioxidants to mitochondria in sepsis
Peer reviewedPublisher PD