324 research outputs found
Sato-Crutchfield formulation for some Evolutionary Games
The Sato-Crutchfield equations are studied analytically and numerically. The
Sato-Crutchfield formulation is corresponding to losing memory. Then
Sato-Crutchfield formulation is applied for some different types of games
including hawk-dove, prisoner's dilemma and the battle of the sexes games. The
Sato-Crutchfield formulation is found not to affect the evolutionarily stable
strategy of the ordinary games. But choosing a strategy becomes purely random
independent on the previous experiences, initial conditions, and the rules of
the game itself. Sato-Crutchfield formulation for the prisoner's dilemma game
can be considered as a theoretical explanation for the existence of cooperation
in a population of defectors.Comment: 9 pages, 3 figures, accepted for Int. J. Mod. Phys.
On managing complex adaptive systems motivated by biosystems application to infections
Many attempts to control Complex adaptive systems (CAS) have failed. Here we try to learn from biosystems to derive some principles for CAS management. An application to managing infections is given
An all-digital ΣΔ--frequency discriminator of arbitrary order
In this paper, we propose an all-digital frequency synthesizer architecture, based on an all-digital ΣΔ-frequency discriminator. The new all-digital synthesizer is compared to previously published work. The architecture of the ΣΔ-frequency discriminator is verified using behavioral simulation
Neoadjuvant chemotherapy versus primary surgery in advanced ovarian carcinoma
BACKGROUND: Patients with advanced ovarian cancer should be treated by radical debulking surgery aiming at complete tumor resection. Unfortunately about 70% of the patients present with advanced disease, when optimal debulking can not be obtained, and therefore these patients gain little benefit from surgery. Neoadjuvant chemotherapy (NACT) has been proposed as a novel therapeutic approach in such cases. In this study, we report our results with primary surgery or neoadjuvant chemotherapy as treatment modalities in the specific indication of operable patients with advanced ovarian carcinoma (no medical contraindication to debulking surgery). PATIENTS AND METHODS: A total of 59 patients with stage III or IV epithelial ovarian carcinomas were evaluated between 1998 and 2003. All patients were submitted to surgical exploration aiming to evaluate tumor resectability. Neoadjuvant chemotherapy was given (in 27 patients) where optimal cytoreduction was not feasible. Conversely primary debulking surgery was performed when we considered that optimal cytoreduction could be achieved by the standard surgery (32 patients). RESULTS: Optimal cytoreduction was higher in the NACT group (72.2%) than the conventional group (62.4%), though not statistically significant (P = 0.5). More important was the finding that parameters of surgical aggressiveness (blood loss rates, ICU stay and total hospital stay) were significantly lower in NACT group than the conventional group. The median overall survival time was 28 months in the conventional group and 25 months in NACT group with a P value of 0.5. The median disease free survival was 19 months in the conventional group and 21 months in NACT group (P = 0.4). In multivariate analysis, the pathologic type and degree of debulking were found to affect the disease free survival significantly. Overall survival was not affected by any of the study parameters. CONCLUSION: Primary chemotherapy followed by interval debulking surgery in select group of patients doesn't appear to worsen the prognosis, but it permits a less aggressive surgery to be performed
A note on q-Euler numbers and polynomials
The purpose of this paper is to construct q-Euler numbers and polynomials by
using p-adic q-integral equations on Zp. Finally, we will give some interesting
formulae related to these q-Euler numbers and polynomials.Comment: 6 page
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