Predicting Sasang Constitution Using Body-Shape Information

Objectives. Body measurement plays a pivotal role not only in the diagnosis of disease but also in the classification of typology. Sasang constitutional medicine, which is one of the forms of Traditional Korean Medicine, is considered to be strongly associated with body shape. We attempted to determine whether a Sasang constitutional analytic tool based on body shape information (SCAT-B) could predict Sasang constitution (SC). Methods. After surveying 23 Oriental medical clinics, 2,677 subjects were recruited and body shape information was collected. The SCAT-Bs for males and females were developed using multinomial logistic regression. Stepwise forward-variable selection was applied using the score statistic and Wald’s test. Results. The predictive rates of the SCAT-B for Tae-eumin (TE), Soeumin (SE), and Soyangin (SY) types in males and females were 80.2%, 56.9%, and 37.7% (males) and 69.3%, 38.9%, and 50.0% (females) in the training set and were 74%, 70.1%, and 35% (males), and 67.4%, 66.3%, and 53.7% (females) in the test set, respectively. Higher constitutional probability scores showed a trend for association with higher predictability. Conclusions. This study shows that the Sasang constitutional analytic tool, which is based on body shape information, may be relatively highly predictive of TE type but may be less predictive when used for SY type

Textile-Based Volatile Organic Compound Sensors Using Cellulose Fabrics and Direct Dyes

In order to fabricate colorimetric textile sensors detecting gas phase of volatile organic compounds (VOCs), 11 kinds of direct dyes were investigated for 13 types of VOCs. Direct Violet 51 was chosen for its best sensing performance both instrumentally and visibly. Direct Violet 51 exhibited the change of color strength and color hue by exposure VOCs. The dyed cotton fabrics detected polar VOCs well, especially N,N-dimethylformamide (DMF). The colorimetric cotton-based textile sensor dyed with Direct Violet 51 exhibited approximately 10 of color difference (ΔE) under 10 ppm DMF gas within 100 min, and the maximum absorption wavelength was shifted from 560 nm to 530 nm. The sensing mechanisms could be summarized in three factors: solvatochromism and aggregative characteristics from the point of view of dye, and adsorption amount of VOCs for fabric. The colorimetric textile sensor retained its sensing performance after 10 cycle tests

Double-gated ultra-thin-body GaAs-on-insulator p-FETs on Si

We demonstrated ultra-thin-body (UTB) junctionless (JL) p-type field-effect transistors (pFETs) on Si using GaAs channels. Wafer bonding and epitaxial lift-off techniques were employed to fabricate the UTB p-GaAs-on-insulator on a Si template. Subsequently, we evaluated the JL FETs having different p-GaAs channel thicknesses considering both maximum depletion width and doping concentration for high performance. Furthermore, by introducing a double-gate operation, we more effectively controlled threshold voltage and attained an even higher ION/IOFF of >106, as well as a low subthreshold swing value of 300 mV/dec

JY: Predicting sasang constitution using body-shape information. Evid Based Complement Alternat Med 2012

Objectives. Body measurement plays a pivotal role not only in the diagnosis of disease but also in the classification of typology. Sasang constitutional medicine, which is one of the forms of Traditional Korean Medicine, is considered to be strongly associated with body shape. We attempted to determine whether a Sasang constitutional analytic tool based on body shape information (SCAT-B) could predict Sasang constitution (SC). Methods. After surveying 23 Oriental medical clinics, 2,677 subjects were recruited and body shape information was collected. The SCAT-Bs for males and females were developed using multinomial logistic regression. Stepwise forward-variable selection was applied using the score statistic and Wald's test. Results. The predictive rates of the SCAT-B for Tae-eumin (TE), Soeumin (SE), and Soyangin (SY) types in males and females were 80.2%, 56.9%, and 37.7% (males) and 69.3%, 38.9%, and 50.0% (females) in the training set and were 74%, 70.1%, and 35% (males), and 67.4%, 66.3%, and 53.7% (females) in the test set, respectively. Higher constitutional probability scores showed a trend for association with higher predictability. Conclusions. This study shows that the Sasang constitutional analytic tool, which is based on body shape information, may be relatively highly predictive of TE type but may be less predictive when used for SY type

Nanoparticle Probes with Surface Enhanced Raman Spectroscopic Tags for Cellular Cancer Targeting

We have developed biocompatible, photostable, and multiplexing-compatible surface-enhanced Raman spectroscopic tagging material (SERS dots) composed of silver nanoparticle-embedded silica spheres and organic Raman labels for cellular cancer targeting in living cells. SERS dots showed linear dependency of Raman signatures on their different amounts, allowing their possibility for the quantification of targets. In addition, the antibody-conjugated SERS dots were successfully applied to the targeting of HER2 and CD10 on cellular membranes and exhibited good specificity. SERS dots demonstrate the potential for high-throughput screening of biomolecules using vibrational information.This work was supported by the Nano Systems Institute- National Core Research Center (NSI-NCRC) program of the Korea Science and Engineering Foundation (KOSEF), Korea. J.-H.K., J.S.K., and H.C. contributed equally to this work

Surface-enhanced Raman spectroscopic-encoded beads for multiplex immunoassay

A new type of encoded bead, which uses surface-enhanced Raman scattering (SERS), is described for multiplex immunoassays. Silver nanoparticles were embedded in sulfonated polystyrene (PS) beads via a polyol method, and they were used as SERS-active substrates. Raman-label organic compounds such as 4-methylbenzenethiol (4-MT), 2-naphthalenethiol (2-NT), and benzenethiol (BT) were then adsorbed onto the silver nanoparticles in the sulfonated PS bead. Although only three kinds of encoding have been demonstrated here, various combinations of these Raman-label organic compounds have the potential to give a large number of tags. The Raman-label-incorporated particles were then coated with a silica shell using tetraethoxyorthosilicate (TEOS) for chemical stability and biocompatibility. The resulting beads showed unique and intense Raman signals for the labeled organic compounds. We demonstrated that SERS-encoded beads could be used for multiplex detection with a model using streptavidin and p53. In our system, the binding event of target molecules and the type of ligand can be simultaneously recognized by Raman spectroscopy using a single laser-line excitation (514.5 nm).This work was supported by the Nano-Systems Institute-National Core Research Center (NSINCRC) program, by the Nano-Bioelectronics and Systems Research Center of KOSEF, Korea, and a grant of the Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea (A050432), and the Brain Korea 21 Program supported by the Ministry of Education and Human Resources Development

Abstracts of 2nd International Symposium on Plastic Pollution

This book presents the abstracts of the selected contributions to the Second International Symposium on Plastic Pollution, hosted from 3rd to 4th of November 2022 in hybrid mode by the “Plastic Free” Specialized Graduate School, University of Seoul. The symposium covers “Challenges and Possible Solutions of Plastic Pollution” and “Toxicity Assessment of Plastics”. The symposium was special as it brought together researchers from multidisciplinary fields, bringing new research ideas and creating collaboration in the field of plastic pollution. With 20 experts from 7 countries and two special sessions with different themes, the symposium offered a perfect platform for attendees to share their research ideas. Symposium Title: 2nd International Symposium on Plastic PollutionTheme: SYM-1~2: Challenges and Possible Solutions of Plastic Pollution. SYM-3: Toxicity Assessment of PlasticsSymposium Date: 3-4 November 2022Symposium Location: Hybrid (online and offline – Jeju-Island Pacific, South Korea)Symposium Organizer: Plastic-Free Specialized Graduate School, University of Seoul, South KoreaSymposium Sponsors: Ministry of Environment & KEITI, South Korea Previous Year Abstract Book: Abstracts of 1st International Symposium on Plastic Pollutio