Multilevel predictors of adolescent physical activity: a longitudinal analysis

<p>Abstract</p> <p>Background</p> <p>To examine how factors from a social ecologic model predict physical activity (PA) among adolescents using a longitudinal analysis.</p> <p>Methods</p> <p>Participants in this longitudinal study were adolescents (ages 10-16 at baseline) and one parent enrolled in the Transdisciplinary Research on Energetics and Cancer-Identifying Determinants of Eating and Activity (TREC-IDEA) and the Etiology of Childhood Obesity (ECHO). Both studies were designed to assess a socio-ecologic model of adolescent obesity risk. PA was collected using ActiGraph activity monitors at two time points 24 months apart. Other measures included objective height and weight, adolescent and parent questionnaires on multilevel psychological, behavioral and social determinants of PA, and a home PA equipment inventory. Analysis was conducted using SAS, including descriptive characteristics, bivariate and stepped multivariate mixed models, using baseline adjustment. Models were stratified by gender.</p> <p>Results</p> <p>There were 578 adolescents with complete data. Results suggest few statistically significant longitudinal associations with physical activity measured as minutes of MVPA or total counts from accelerometers. For boys, greater self-efficacy (B = 0.75, <it>p </it>= 0.01) and baseline MVPA (B = 0.55, <it>p </it>< 0.01) remained significantly associated with MVPA at follow-up. A similar pattern was observed for total counts. For girls, baseline MVPA (B = 0.58, <it>p </it>= 0.01) and barriers (B = -0.32, <it>p </it>= 0.05) significantly predicted MVPA at follow-up in the full model. The full multilevel model explained 30% of the variance in PA among boys and 24% among girls.</p> <p>Conclusions</p> <p>PA change in adolescents is a complex issue that is not easily understood. Our findings suggest early PA habits are the most important predictor of PA levels in adolescence. Intervention may be necessary prior to middle school to maintain PA through adolescence.</p

How we eat what we eat: identifying meal routines and practices most strongly associated with healthy and unhealthy dietary factors among young adults

Abstract Objective (i) To examine associations between young adults’ meal routines and practices (e.g. food preparation, meal skipping, eating on the run) and key dietary indicators (fruit/vegetable, fast-food and sugar-sweetened beverage intakes) and (ii) to develop indices of protective and risky meal practices most strongly associated with diet. Design Cross-sectional survey. Setting Minneapolis/St. Paul metropolitan area, Minnesota (USA). Subjects A diverse sample of community college and public university students ( n 1013). Results Meal routines and practices most strongly associated with healthy dietary patterns were related to home food preparation (i.e. preparing meals at home, preparing meals with vegetables) and meal regularity (i.e. routine consumption of evening meals and breakfast). In contrast, factors most strongly associated with poor dietary patterns included eating on the run, using media while eating and purchasing foods/beverages on campus. A Protective Factors Index, summing selected protective meal routines and practices, was positively associated with fruit/vegetable consumption and negatively associated with fast-food and sugar-sweetened beverage consumption ( P &lt;0·001). A Risky Factors Index yielded significant, positive associations with fast-food and sugar-sweetened beverage consumption ( P &lt;0·001). The probability test for the association between the Risky Factors Index and fruit/vegetable intake was P= 0·05. Conclusions Meal routines and practices were significantly associated with young adults’ dietary patterns, suggesting that ways in which individuals structure mealtimes and contextual characteristics of eating likely influence food choice. Thus, in addition to considering specific food choices, it also may be important to consider the context of mealtimes in developing dietary messaging and guidelines

The Relationship of Area-Level Sociodemographic Characteristics, Household Composition and Individual-Level Socioeconomic Status on Walking Behavior Among Adults

Understanding the contextual factors associated with why adults walk is important for those interested in increasing walking as a mode of transportation and leisure. This paper investigates the relationships between neighborhood-level sociodemographic context, individual level sociodemographic characteristics and walking for leisure and transport. Data from two community-based studies of adults (n = 550) were used to determine the association between the Area Sociodemographic Environment (ASDE), calculated from U.S. Census variables, and individual-level SES as potential correlates of walking behavior. Descriptive statistics, mean comparisons and Pearson’s correlations coefficients were used to assess bivariate relationships. Generalized estimating equations were used to model the relationship between ASDE, as quartiles, and walking behavior. Adjusted models suggest adults engage in more minutes of walking for transportation and less walking for leisure in the most disadvantaged compared to the least disadvantaged neighborhoods but adding individual level demographics and SES eliminated the significant results. However, when models were stratified for free or reduced cost lunch, of those with children who qualified for free or reduced lunch, those who lived in the wealthiest neighborhoods engaged in 10.7 min less of total walking per day compared to those living in the most challenged neighborhoods (p < 0.001). Strategies to increase walking for transportation or leisure need to take account of individual level socioeconomic factors in addition to area-level measures

Coilin Phosphomutants Disrupt Cajal Body Formation, Reduce Cell Proliferation and Produce a Distinct Coilin Degradation Product

Coilin is a nuclear phosphoprotein that accumulates in Cajal bodies (CBs). CBs participate in ribonucleoprotein and telomerase biogenesis, and are often found in cells with high transcriptional demands such as neuronal and cancer cells, but can also be observed less frequently in other cell types such as fibroblasts. Many proteins enriched within the CB are phosphorylated, but it is not clear what role this modification has on the activity of these proteins in the CB. Coilin is considered to be the CB marker protein and is essential for proper CB formation and composition in mammalian cells. In order to characterize the role of coilin phosphorylation on CB formation, we evaluated various coilin phosphomutants using transient expression. Additionally, we generated inducible coilin phosphomutant cell lines that, when used in combination with endogenous coilin knockdown, allow for the expression of the phosphomutants at physiological levels. Transient expression of all coilin phosphomutants except the phosphonull mutant (OFF) significantly reduces proliferation. Interestingly, a stable cell line induced to express the coilin S489D phosphomutant displays nucleolar accumulation of the mutant and generates a N-terminal degradation product; neither of which is observed upon transient expression. A N-terminal degradation product and nucleolar localization are also observed in a stable cell line induced to express a coilin phosphonull mutant (OFF). The nucleolar localization of the S489D and OFF coilin mutants observed in the stable cell lines is decreased when endogenous coilin is reduced. Furthermore, all the phosphomutant cells lines show a significant reduction in CB formation when compared to wild-type after endogenous coilin knockdown. Cell proliferation studies on these lines reveal that only wild-type coilin and the OFF mutant are sufficient to rescue the reduction in proliferation associated with endogenous coilin depletion. These results emphasize the role of coilin phosphorylation in the formation and activity of CBs

Nourish Plus Nature: Impacting the Double Child Development Burden in the First 1000 Days

Mary Hearst, Ph.D. in Epidemiology, Program Director for Master of Public Health & Associate Professor was awarded $15,000 by the GHR Innovative Scholarships to conduct a formative assessment to prepare a grant submission to optimize child development in Indonesia. Early childhood development is not a luxury but is critical to improving longer term child outcomes. Optimizing healthy development among children ages 0-5 is key for individual, family and community health and development. Key factors for optimal child development and life-long well-being include adequate nutrition and an environment that supports optimal development. Inadequate nutrition impedes physical growth, and early malnutrition can effect brain function, cognitive ability and behavior. The goal of the project is to improve ‘nutrition’ and ‘nurture’ among children ages 0-5 and their mothers in Indonesia. This long term project offers the opportunity to expand a well-designed and effective nutrition-oriented intervention in a LMIC and test the additive or multiplicative impact of the Care for Children Development Model

Household Dietary Diversity among Households with and without Children with Disabilities in Three Low-Income Communities in Lusaka, Zambia

The purpose of this manuscript is to describe household dietary diversity (HDDS) in Lusaka, Zambia between households with and without a child with a disability living in the same communities. Cross-sectional data were collected in three low-income compounds in September 2021. Participants included households with a child with a disability enrolled in Kusamala+, a community-based program, (n = 444) and a convenience sample of adults living in the same area without a child with a disability (n = 1027). The HDDS tool asked about food groups consumed in the past 24 h by people in the household. The responses were summed (yes = 1, no = 0), range 0&ndash;12. Individual dietary diversity scores (IDDSs) were calculated for children (0&ndash;8 items). Analysis included descriptive statistics and linear regression. Mean HDDS for the households with a child with a disability was 4.8 (SD 2.1) vs. 6.1 (SD = 2.2) among households without a child with a disability (p &lt; 0.001). The individual score for children (IDDS) for households with children with disabilities was 2.6 (SD = 1.4) vs. 3.7 (SD = 1.6) for households without a child with a disability. Households with a child with a disability had a significantly lower HDDS and IDDS in unadjusted and adjusted models (p &lt; 0.001). National policy must assure the most vulnerable populations, and often hidden, receive focused financial and food support

Increasing Fruit and Vegetable Consumption and Offerings to Somali Children

Objective : To determine the feasibility, acceptability, and impact of a parent-centered intervention to increase fruit and vegetable servings and consumption among Somali children living in the United States. Design : Pilot intervention that included Somali community health workers who organized groups of 3 or 4 women to participate in 2 initial educational sessions, including topics of health and nutrition, serving size, and label reading. A third session taught interactive cooking to increase skills in preparing fruits and vegetables and increasing the numbers of vegetables included in traditional Somali dishes. The final session was a trip to the grocery store to identify fruits and vegetables, determine ripeness, and explore frozen and canned fruits and vegetables for halal, low-sodium, and low-sugar products. Surveys were completed pre- and post-intervention. Setting : Study participants were recruited from a large housing complex in Minneapolis, Minnesota, with a high population of Somali immigrants. Participants : Somali women (N = 25) with children aged 3 to 10 years. Results : The intervention was feasible and well accepted. In comparing pre- and post-intervention surveys, mothers reported providing their children significantly more frequent servings of fruits and vegetables at dinner, lunch, snack, and breakfast (vegetable only). There was a statistically significant increase in parent-reported intake of fruits and vegetables for themselves and their children. Conclusion : The FAV-S study was feasible and acceptable, and it demonstrated potential for increasing fruit and vegetable servings and consumption among Somali children. A larger-scale randomized trial is needed to assess the impact of this intervention

Dog Ownership and Adolescent Physical Activity

Background—Positive associations between dog ownership and adult health outcomes have been observed, but research involving youth is lacking. Purpose—The purpose of this study was to assess the relationship of family dog ownership to adolescent and parent physical activity, weight status, and metabolic risk factors. Methods—Data were collected on dog ownership in 618 adolescent/parent pairs between 9/2006 and 6/2008 and analyzed in 2010. Adolescent physical activity was assessed by ActiGraph accelerometers. Trained staff measured blood pressure, height and weight, and percentage body fat was calculated by impedance. A subsample of adolescents (n=318) opted for a fasting blood draw used to derive a metabolic risk cluster score. Parents and adolescents provided consent and assent, respectively. Results—Adolescents’ mean age was 14.6±1.8 years and 49% were male. White and higher SES adolescents were more likely to own a dog. In models adjusted for age, puberty, gender, race, total household members and SES, adolescent physical activity (mean counts min−1 day−1) remained significantly associated with dog ownership (β=24.3, SE=12.4, p=0.05) while the association with minutes of moderate-to-vigorous physical activity day−1 became nonsignificant (β=2.2, SE=1.2, p=0.07). No significant results were observed for other adolescent characteristics. Conclusions—Dog ownership was associated with more physical activity among adolescents. Further research using longitudinal data will help clarify the role that dog ownership may have on adolescent physical activity

Using Community-based Interventions to Reduce Public Stigma of Children with Disabilities: A Feasibility Study

Background: Public stigma, or negative community-held beliefs, about children with disabilities (CWDs) often leads to negative outcomes for CWD and their families. This study considers the effectiveness of four community-level interventions to reduce public stigma in two Lusaka, Zambia communities. Methods: This feasibility study describes four community-based interventions to provide education to consider whether perceptions of attitudes and stigma towards CWD changed after implementing four educational interventions. Results: Results revealed that these interventions were achievable. Preliminary multiple regression analyses indicated a significant impact of attending an event on the attitude scale, while no effect on the stigma scale. Presence at multiple anti-stigma events exhibited no effect for the stigma scale, while the attitude scale showed significance. Discussion: This study builds on the limited research available in low-income countries to reduce public stigma towards CWD, with the hope of enhance quality of life for CWD and their families